Adjunctive therapy with brinzolamide in patients on travoprost treatment
Introduction. This study was aimed at evaluating the safety and efficacy of brinzolamide 1% suspension (Azopt? 1%) and travoprost 0.004% (Travatan?) combined therapy in patients with open-angle glaucoma or ocular hypertension who are in need of additional intraocular pressure lowering. Material and methods.
Nikola Babic+4 more
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PurposeThe purpose of this study was to investigate the effect of a 1% brinzolamide and 0.1% brimonidine fixed combination (BBFC) on ONH blood flow (BF) in rabbits.MethodsA crossover study was conducted on pigmented rabbits; a physiological saline ...
Nana Takahashi+5 more
doaj +1 more source
The acute and chronic effects of intravitreal anti-vascular endothelial growth factor injections on intraocular pressure: A review [PDF]
The acute and chronic effects of repeated intravitreal antivascular endothelial growth factor (VEGF) injections on intraocular pressure have not been fully characterized, and the development of sustained ocular hypertension could adversely affect ...
Bracha, Peter+4 more
core +1 more source
Development and Validation of Stability Indicating RP-HPLC Method for Estimation of Cilnidipine [PDF]
Cilnidipine is one of the dihydropyridine calcium antagonists. It was created combinedly by Fuji Viscera Pharmaceutical Company, Ajinomoto and Japan and was approved in the year 1995.
Kulkarni, Amol+2 more
core +2 more sources
Efficacy of topical brinzolamide in children with retinal dystrophies
Background: Inherited retinal dystrophies are a leading cause of irreversible blindness in children in the United States. Topical carbonic anhydrase inhibitors have improved central vision and cystoid macular edema in patients with retinal dystrophies, but few studies have assessed their efficacy in children.
Arlene V. Drack+9 more
openaire +5 more sources
Mucoadhesive brinzolamide-loaded nanofibers for alternative glaucoma treatment
Despite the advances in the field of pharmaceutical materials and technology, topical administration remains a method of choice for the treatment of eye diseases such as glaucoma, with eye drops being a leading dosage form. Their main disadvantage is a very short drug residence time and thus poor drug bioavailability, leading to the necessity of ...
Olga Cegielska+4 more
openaire +2 more sources
Bilateral Choroidal Detachment Induced by Unilateral Application of a Fixed Combination of Topical Timolol Maleate and Brinzolamide [PDF]
We describe a 66-year-old man who developed bilateral choroidal detachment that was induced by unilateral topical administration of a fixed combination of 1% brinzolamide and 0.5% timolol maleate the day after an uneventful phacoemulsification surgery ...
DONMEZ, Oya+3 more
core +3 more sources
The physiological role of carbonic anhydrases in pH and ion regulation is crucial to insect survival. We examined the toxic and neurophysiological effects of five carbonic anhydrase inhibitors (CAIs) against Aedes aegypti.
Sheena A. M. Francis+3 more
doaj +1 more source
Evaluation of the Use of Brinzolamide-Brimonidine Fixed Combination in Maximum Medical Therapy
Objectives:To investigate the intraocular pressure (IOP)-lowering efficacy, safety, and treatment tolerability of brinzolamide/ brimonidine fixed combination (BBFC) in maximum medical therapy.Materials and Methods:The medical records of 92 patients with ...
Oya Tekeli, Helin Ceren Köse
doaj +1 more source
Safety and Efficacy of Adding Fixed-Combination Brinzolamide/Timolol Maleate to Prostaglandin Therapy for Treatment of Ocular Hypertension or Glaucoma [PDF]
Purpose. To evaluate the safety and efficacy of adding brinzolamide 1%/timolol maleate 0.5% fixed combination (BTFC) to a prostaglandin analog (PGA). Methods. This was a 12-week, open-label, single-arm study of patients with open-angle glaucoma or ocular
Anton Hommer+2 more
core +3 more sources