Antiproliferative Activity of (−)‐Isopulegol‐based 1,3‐Oxazine, 1,3‐Thiazine and 2,4‐Diaminopyrimidine Derivatives [PDF]
ChemistryOpen, 2022 A series of novel heterocyclic structures, namely 1,3‐oxazines, 1,3‐thiazines and 2,4‐diaminopyrimidines, were designed and synthesised. The bioassay tests demonstrated that, among these analogues, 2,4‐diaminopyridine derivatives showed significant ...
Fatima Z. Bamou +6 more
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Dithieno[1,4]thiazines and Bis[1]benzothieno[1,4]thiazines—Organometallic Synthesis and Functionalization of Electron Density Enriched Congeners of Phenothiazine [PDF]
Molecules, 2020 This mini-review summarizes the syntheses and functionalizations of dithieno[1,4]thiazines and bis[1]benzothieno[1,4]thiazines, both electron density-enriched congeners of phenothiazines with remarkable electronic properties.
Lars May, Thomas J. J. Müller
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Green Synthesis of 2-Mercapto 5,6-Dihydro-4H-1,3-Thiazines via Sequential C–S Couplings [PDF]
MoleculesThe six-membered N,S-heterocyclic 1,3-thiazines and their derivatives are widely acknowledged as pharmaceutical molecules with a wide range of biological activities.
Wenjie Liu +4 more
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Gold-Catalyzed 1,3-Thiazine Formation and Uncommon Tautomer Isolation. [PDF]
J Org Chem, 2022 This work represents the first example of a gold-catalyzed formation of 1, 3-thiazine/1, 3-thiazinane by means of a catalytic approach and further uncommon isolation of the two tautomers.
Canudo-Barreras G +3 more
europepmc +3 more sources
Synthesis of 1,3-Thiazine and 1,4-Thiazepine Derivatives via Cycloadditions and Ring Expansion. [PDF]
Int J Mol SciNon-cephem drugs with 1,3-thiazine-derived rings are very rare, although a number of bioactive 1,3-thiazine derivatives are known. Similarly, 1,4-thiazepine-derived drugs are rare, but many 1,4-thiazepine derivatives show interesting biological ...
Palkó M +4 more
europepmc +3 more sources
S,N-Heteropentacenes – Syntheses of Electron-Rich Anellated Pentacycles
Organic Materials, 2021 This review summarizes syntheses of S,N-heteropentacenes, i.e. electron-rich sulfur and nitrogen-embedding pentacycles, and briefly highlights selected applications in molecular electronics. Depending on the anellation mode and the number of incorporated
Henning R. V. Berens +1 more
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Chemistry Proceedings, 2021 The present work is devoted to the synthesis of imidazo[2,1-b][1,3]thiazine derivatives as possible anti-inflammatory agents. The synthetic approach to (2-pyridinyloxy) substituted imidazo[2,1-b][1,3]thiazines based on the interaction of the ...
Nataliia Slyvka +3 more
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Synthesis and Chemical Characterization of Some NovelAzachalcones compounds and Evaluation of their Biological Activity [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 : A series of novel Azachalcone compounds were prepared by the reaction of 3-acetyl pyridine with different aromatic aldehyd . Azachalcone was reacted with thiourea to give good yields of thiazines , all the new compounds were characterized by I.R , U.V ...
Mohammed Abed Kadhim
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Molecules, 2021 In this article, we showed the synthesis of new polycyclic aromatic compounds, such as thienotriazolopyrimidinones, N-(thienotriazolopyrimidine) acetamide, 2-mercapto-thienotriazolo-pyrimidinones, 2-(((thieno-triazolopyrimidine) methyl) thio) thieno ...
Ameen Ali Abu-Hashem +2 more
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Frontiers in Cell and Developmental Biology, 2020 Over the past decade, thiazines, thiadiazoles, and thiohydrazides have attracted increasing attention due to their sedative, antimicrobial, antiviral, antifungal, and antitumor activities.
Anastasiia A. Zakharova +5 more
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