Results 11 to 20 of about 2,614 (189)

1,2,3-Triazole-4(5)-amines – Convenient Synthetic Blocks for the Construction of Triazolo-Annulated Heterocycles

open access: yesЖурнал органічної та фармацевтичної хімії, 2022
Aim. To analyze and summarize the synthetic potential of 1,2,3-triazole-4(5)-amines as efficient building blocks in the synthesis of triazolo-annulated pyridine, azine and azepine systems. Results and discussion.
Natalia O. Syrota   +3 more
doaj   +1 more source

Molar ratios of therapeutic water-soluble phenothiazine⋅water-insoluble phospholipid adducts reveal a Fibonacci correlation and a putative link for structure–activity relationships [PDF]

open access: yes, 2015
The fact that non-antibiotics can sensitise microorganisms for antibiotic treatment suggests that these molecules have valuable potential to treat multiple drug resistance.
Fey, S. J.   +3 more
core   +1 more source

Synthesis of imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines via a base-induced rearrangement of functionalized imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazines

open access: yesBeilstein Journal of Organic Chemistry, 2023
A series of imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines was synthesized via a cascade sequence of hydrolysis and skeletal rearrangement of imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazin-7(8H)-ylidene)acetic acid esters in methanol upon treatment with
Dmitry B. Vinogradov   +4 more
doaj   +1 more source

Stereoselective Synthesis and Cytoselective Toxicity of Monoterpene-Fused 2-Imino-1,3-thiazines

open access: yesMolecules, 2014
Starting from pinane-, apopinane- and carane-based 1,3-amino alcohols obtained from monoterpene-based β-amino acids, a library of monoterpene-fused 2-imino-1,3-thiazines as main products and 2-thioxo-1,3-oxazines as side-products were prepared via two ...
Zsolt Szakonyi   +3 more
doaj   +1 more source

Doença de Fabry - importância do rastreamento em córnea verticilata: relato de caso [PDF]

open access: yes, 2011
Fabry disease is an X-linked disease of glycosphingolipid (GL) metabolism. The accumulation of GL in tissues can affect multiple organ systems. Initial symptoms includes episodes of severe pain in the extremities, cornea verticillata and skin lesions. In
Arantes, Tiago Eugênio Faria e   +2 more
core   +2 more sources

Bioactive Thiazine and Benzothiazine Derivatives: Green Synthesis Methods and Their Medicinal Importance

open access: yesMolecules, 2016
Thiazines are a group of heterocyclic organic compounds that are still largely unexplored for their pharmacological activities. There are different available methods for the synthesis of thiazine derivatives in the literature.
Syed Lal Badshah, Abdul Naeem
doaj   +1 more source

Facile Synthesis of Some Novel Pyrido[3', 2': 4, 5]thieno[2,3-b][1,4]thiazine-8-carboxylic Acids

open access: yesMolecules, 2007
Model tetrahydropyrido[3',2':4,5]thieno[2,3-b][1,4]thiazines 9a-c were synthesized via reductive lactamization, using sodium dithionite, of the respective 2-[(carboxyalkyl)thio]-3-nitro-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylic acids 7a-c. The latter
Salim S Sabri   +4 more
doaj   +1 more source

Physiologie de l’acte sexuel masculin : Son vieillissement et ses problèmes inhérents [PDF]

open access: yes, 1980
L'auteur discute la physiologie de l'acte sexuel mâle et les problèmes inhérents au vieillissement. Il débute en faisant une revue de la physiologie sexuelle et décrit ensuite les trois étapes de l'acte sexuel : érection, orgasme et ses deux sous-étapes.
Coulonval, Louis
core   +1 more source

Redox properties of methylene blue as a promising photometric reagent for determination of halogen oxidants [PDF]

open access: yes, 2015
Постановка задачи исследования заключалась в изучении взаимодействий в окислительно-восстановительных системах, содержащих различные кислотно-основные формы тиазинового красителя метиленового голубого, используемого в качестве фотометрического реагента ...
Elipasheva, E. V.   +7 more
core   +1 more source

Thiosulfonate‐Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling

open access: yesAngewandte Chemie, Volume 138, Issue 6, 2 February 2026.
We present a powerful photochemical strategy for converting disulfide bonds into stable thioether linkages via a [1,2]‐sigmatropic rearrangement. By integrating this reaction into traditional methanethiosulfonate‐based thiol labeling, we enable light‐triggered stabilization of peptide and protein conjugates with enhanced robustness and versatility ...
Lucie Šálková   +4 more
wiley   +2 more sources

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