Aim. To analyze and summarize the synthetic potential of 1,2,3-triazole-4(5)-amines as efficient building blocks in the synthesis of triazolo-annulated pyridine, azine and azepine systems. Results and discussion.
Natalia O. Syrota +3 more
doaj +1 more source
Molar ratios of therapeutic water-soluble phenothiazine⋅water-insoluble phospholipid adducts reveal a Fibonacci correlation and a putative link for structure–activity relationships [PDF]
The fact that non-antibiotics can sensitise microorganisms for antibiotic treatment suggests that these molecules have valuable potential to treat multiple drug resistance.
Fey, S. J. +3 more
core +1 more source
A series of imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines was synthesized via a cascade sequence of hydrolysis and skeletal rearrangement of imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazin-7(8H)-ylidene)acetic acid esters in methanol upon treatment with
Dmitry B. Vinogradov +4 more
doaj +1 more source
Stereoselective Synthesis and Cytoselective Toxicity of Monoterpene-Fused 2-Imino-1,3-thiazines
Starting from pinane-, apopinane- and carane-based 1,3-amino alcohols obtained from monoterpene-based β-amino acids, a library of monoterpene-fused 2-imino-1,3-thiazines as main products and 2-thioxo-1,3-oxazines as side-products were prepared via two ...
Zsolt Szakonyi +3 more
doaj +1 more source
Doença de Fabry - importância do rastreamento em córnea verticilata: relato de caso [PDF]
Fabry disease is an X-linked disease of glycosphingolipid (GL) metabolism. The accumulation of GL in tissues can affect multiple organ systems. Initial symptoms includes episodes of severe pain in the extremities, cornea verticillata and skin lesions. In
Arantes, Tiago Eugênio Faria e +2 more
core +2 more sources
Thiazines are a group of heterocyclic organic compounds that are still largely unexplored for their pharmacological activities. There are different available methods for the synthesis of thiazine derivatives in the literature.
Syed Lal Badshah, Abdul Naeem
doaj +1 more source
Facile Synthesis of Some Novel Pyrido[3', 2': 4, 5]thieno[2,3-b][1,4]thiazine-8-carboxylic Acids
Model tetrahydropyrido[3',2':4,5]thieno[2,3-b][1,4]thiazines 9a-c were synthesized via reductive lactamization, using sodium dithionite, of the respective 2-[(carboxyalkyl)thio]-3-nitro-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylic acids 7a-c. The latter
Salim S Sabri +4 more
doaj +1 more source
Physiologie de l’acte sexuel masculin : Son vieillissement et ses problèmes inhérents [PDF]
L'auteur discute la physiologie de l'acte sexuel mâle et les problèmes inhérents au vieillissement. Il débute en faisant une revue de la physiologie sexuelle et décrit ensuite les trois étapes de l'acte sexuel : érection, orgasme et ses deux sous-étapes.
Coulonval, Louis
core +1 more source
Redox properties of methylene blue as a promising photometric reagent for determination of halogen oxidants [PDF]
Постановка задачи исследования заключалась в изучении взаимодействий в окислительно-восстановительных системах, содержащих различные кислотно-основные формы тиазинового красителя метиленового голубого, используемого в качестве фотометрического реагента ...
Elipasheva, E. V. +7 more
core +1 more source
Thiosulfonate‐Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling
We present a powerful photochemical strategy for converting disulfide bonds into stable thioether linkages via a [1,2]‐sigmatropic rearrangement. By integrating this reaction into traditional methanethiosulfonate‐based thiol labeling, we enable light‐triggered stabilization of peptide and protein conjugates with enhanced robustness and versatility ...
Lucie Šálková +4 more
wiley +2 more sources

