Broad autism phenotype is characterized by impairments in cognitive, social, communicative, behavioral and personality domains of close relatives to autistic individuals.
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The Broad Autism Phenotype Questionnaire: Prevalence and Diagnostic Classification [PDF]
The Broad Autism Phenotype Questionnaire (BAPQ; Hurley et al, 2007) was administered to a large community-based sample of biological parents of children with autism (PCAs) and comparison parents (CPs) (n = 1692). Exploratory factor analysis and internal consistency parameters confirmed a robust three factor structure of the BAPQ, corresponding to the ...
Noah J Sasson +2 more
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Amygdala and hippocampal contributions to broad autism phenotype: Project Ice Storm [PDF]
Prenatal maternal stress (PNMS) increases the risk for autism, and individuals with autism inconsistently exhibit increased or decreased volumes and functional connectivity of the whole amygdala and the whole hippocampus.
Xinyuan Li +6 more
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A broad autism phenotype expressed in facial morphology. [PDF]
AbstractAutism spectrum disorder is a heritable neurodevelopmental condition diagnosed based on social and communication differences. There is strong evidence that cognitive and behavioural changes associated with clinical autism aggregate with biological relatives but in milder form, commonly referred to as the ‘broad autism phenotype’.
Tan DW +6 more
europepmc +7 more sources
Brief Report: The Broad Autism Phenotype in Swedish Parents of Children With and Without Autism Spectrum Conditions. [PDF]
AbstractThe broad autism phenotype (BAP) is a set of characteristics often observed in typically developing people with a genetic load for autism, such as parents of autistic children. The Broad Autism Phenotypic Questionnaire (BAPQ) is a 36-item questionnaire developed to identify the BAP in first-degree relatives of autistic people. We translated the
Bang P +3 more
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Autism and the broad autism phenotype: familial patterns and intergenerational transmission. [PDF]
Features of the Broad Autism Phenotype (BAP) are disproportionately prevalent in parents of a child with autism, highlighting familial patterns indicative of heritability. It is unclear, however, whether the presence of BAP features in both parents confers an increased liability for autism.
Sasson NJ +4 more
europepmc +7 more sources
Neuropsychological profile of autism and the broad autism phenotype. [PDF]
There now exist multiple reports of a constellation of language, personality, and social-behavioral features present among relatives that mirror the symptom domains of autism, but much milder in expression. Studies of this ‘broad autism phenotype’ (BAP) may provide a potentially important, complementary approach for detecting the genes causing autism ...
Losh M +6 more
europepmc +8 more sources
Broad Autism Phenotype Questionnaire – Translation and Validation in a South Indian Language [PDF]
Background and Objectives: Broad Autism Phenotype (BAP) refers to specific behaviors or minor deficits in social/communication skills not meeting the diagnostic criteria for autism spectrum disorders (ASDs).
Betsy Baby +8 more
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The broad autism phenotype in parents of individuals with autism: a systematic review of the literature [PDF]
The broad autism phenotype (BAP) is a milder manifestation of the defining symptoms of the syndrome in individuals without autism. This study conducted a systematic review of studies about behavioral characteristics of interpersonal relationships ...
Lidia Prata Cruz +2 more
doaj +6 more sources
Sex Differences in the Broad Autism Phenotype: Insights from the Australian Biobank. [PDF]
Abstract Examining sub-threshold autistic traits in non-autistic first-degree relatives of individuals on the autism spectrum, known as the Broad Autism Phenotype (BAP), could provide new insights into the associations and familial aggregation of autistic traits.
Di Mento B +6 more
europepmc +6 more sources

