Results 31 to 40 of about 39,746 (275)

The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population

Molecular Autism, 2021
Background Traits and characteristics qualitatively similar to those seen in diagnosed autism spectrum disorder can be found to varying degrees in the general population.
Michael C. W. English, Gilles E. Gignac, Troy A. W. Visser, Andrew J. O. Whitehouse, James T. Enns, Murray T. Maybery   +5 more
doaj   +1 more source

A Relationship between the Broader Autism Phenotype and empathy among students

Primenjena Psihologija, 2022
Previous research has shown that persons with a higher level of the broad autism phenotype (BAP) experience deficits in empathy. The aim of the present study is to investigate a multivariate relationship between the BAP and different aspects of empathy.
Bojan Dučić, Svetlana Kaljača, Irena Stojković   +2 more
doaj   +1 more source

A Study of the Wellbeing of Siblings of Children with Autism Spectrum Disorders: Sibling Efficacy, Positive and Negative Affect, and Coping Strategies [PDF]

, 2018
Autism spectrum disorders (ASD) include pervasive developmental disorders characterised by communication deficits, difficulty with social understanding, and repetitive behaviors.
Habelrih, Emily Anne, Hicks, Richard E., Vanstone, Daisy   +2 more
core   +1 more source

The Phenotypic Profile Associated With the FMR1 Premutation in Women: An Investigation of Clinical-Behavioral, Social-Cognitive, and Executive Abilities

Frontiers in Psychiatry, 2021
The FMR1 gene in its premutation (PM) state has been linked to a range of clinical and subclinical phenotypes among FMR1 PM carriers, including some subclinical traits associated with autism spectrum disorder (ASD).
Nell Maltman, Nell Maltman, Janna Guilfoyle, Kritika Nayar, Gary E. Martin, Molly Winston, Joseph C. Y. Lau, Lauren Bush, Shivani Patel, Michelle Lee, John Sideris, Deborah A. Hall, Lili Zhou, Kevin Sharp, Elizabeth Berry-Kravis, Molly Losh   +15 more
doaj   +1 more source

Investigating the structure of the autism-spectrum quotient using Mokken scaling [PDF]

, 2015
Traits similar to those shown in autism spectrum condition (ASC) are apparent in relatives of individuals with ASC, and in the general population without necessarily meeting diagnostic criteria for an ASC.
Allison, Carrie, Baron-Cohen, Simon, Stewart, Mary E., Watson, Roger   +3 more
core   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

A Longitudinal Study of Parent-Child Interactions and Language Outcomes in Fragile X Syndrome and Other Neurodevelopmental Disorders

Frontiers in Psychiatry, 2021
Difficulties with pragmatic language (i.e., language in social contexts, such as conversational ability) are a noted characteristic of the language profiles of both fragile X syndrome (FXS) and autism spectrum disorder (ASD), conditions which show ...
Lauren Bush, Lauren Bush, Gary E. Martin, Emily Landau, Molly Losh   +4 more
doaj   +1 more source

Changes in the Number and Morphology of Dendritic Spines in the Hippocampus and Prefrontal Cortex of the C58/J Mouse Model of Autism

Frontiers in Cellular Neuroscience, 2021
Autism spectrum disorder (ASD) has a broad range of neurobiological characteristics, including alterations in dendritic spines, where approximately 90% of excitatory synapses occur.
Isabel Barón-Mendoza, Emely Maqueda-Martínez, Mónica Martínez-Marcial, Marisol De la Fuente-Granada, Margarita Gómez-Chavarin, Aliesha González-Arenas   +5 more
doaj   +1 more source

Sex Differences in the Broad Autism Phenotype: Insights from the Australian Biobank. [PDF]

J Autism Dev Disord
Abstract Examining sub-threshold autistic traits in non-autistic first-degree relatives of individuals on the autism spectrum, known as the Broad Autism Phenotype (BAP), could provide new insights into the associations and familial aggregation of autistic traits.
Di Mento B, John JR, Diaz AM, Lin PI, Masi A, Grove R, Eapen V.   +6 more
europepmc   +4 more sources

Psychiatric genetics and the structure of psychopathology [PDF]

, 2018
For over a century, psychiatric disorders have been defined by expert opinion and clinical observation. The modern DSM has relied on a consensus of experts to define categorical syndromes based on clusters of symptoms and signs, and, to some extent ...
Andreassen, Ole A., Edenberg, Howard J., Faraone, Stephen V., Glatt, Stephen J., Kendler, Kenneth S., Smoller, Jordan W.   +5 more
core   +1 more source