Results 51 to 60 of about 1,885,121 (275)

Context effects: discourse structure influences narrative ability in autism and first-degree relatives

Frontiers in Psychiatry
IntroductionNarrative, or storytelling, ability is a well-documented area of difficulty in autism spectrum disorder (ASD) and is an important skill that is related to social-communicative success.
Emily Landau, Kritika Nayar, Kritika Nayar, Gary E. Martin, Cassandra Stevens, Cassandra Stevens, Jiayin Xing, Jiayin Xing, Janna Guilfoyle, Joseph C. Y. Lau, Molly Losh   +10 more
doaj   +1 more source

Language in autism and specific language impairment: Where are the links? [PDF]

, 2008
It has been suggested that language impairment in autism is behaviourally, neurobiologically, and etiologically related to specific language impairment (SLI).
Williams, David M., Botting, N., Williams, D., Boucher, J., Botting, Nicola, Boucher, Jill   +5 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Broad autism phenotype: theory of mind and empathy skills in unaffected siblings of children with autism spectrum disorder

Psychiatry and Clinical Psychopharmacology, 2018
OBJECTIVE: Difficulties in social communication is core syptoms of autism spectrum disorder (ASD), and it is often present in first-degree relatives in varying degrees.
Murat Eyuboglu, Burak Baykara, Damla Eyuboglu   +2 more
doaj   +1 more source

Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder. [PDF]

PLoS ONE, 2015
Autism spectrum disorder comprises several neurodevelopmental conditions presenting symptoms in social communication and restricted, repetitive behaviors.
Daniela Brunner, Patricia Kabitzke, Dansha He, Kimberly Cox, Lucinda Thiede, Taleen Hanania, Emily Sabath, Vadim Alexandrov, Michael Saxe, Elior Peles, Alea Mills, Will Spooren, Anirvan Ghosh, Pamela Feliciano, Marta Benedetti, Alice Luo Clayton, Barbara Biemans   +16 more
doaj   +1 more source

Evaluating the theory of executive dysfunction in autism [PDF]

, 2004
In this paper studies of executive function in autism spectrum disorder are reviewed. Executive function is an umbrella term for functions such as planning, working memory, impulse control, inhibition, and shifting set, as well as for the initiation and ...
Hill, Elisabeth L.
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Sex differences and within-family associations in the broad autism phenotype [PDF]

Autism, 2012
While there is a strong sex bias in the presentation of autism, it is unknown whether this bias is also present in subclinical manifestations of autism among relatives, or the broad autism phenotype. This study examined this question and investigated patterns of co-occurrence of broad autism phenotype traits within families of individuals with autism ...
Klusek, Jessica, Losh, M, Martin, G
openaire   +2 more sources

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Psychotic Spectrum Symptoms in Adults with Autism Spectrum Disorder and in Their First-Degree Relatives

Brain Sciences
Objectives: Autism Spectrum Disorder (ASD) and psychotic disorders have long been considered separate diagnostic entities, yet increasing evidence highlights shared neurodevelopmental mechanisms and symptom overlap.
Benedetta Nardi, Francesca Parri, Stefano Pini, Federico Giovannoni, Cristiana Pronestì, Silvia Tarantino, Gabriele Massimetti, Ivan Mirko Cremone, Liliana Dell’Osso, Barbara Carpita   +9 more
doaj   +1 more source