Results 41 to 50 of about 19,233 (265)

Child behavior problems and parental well-being in families of children with autism : the mediating role of mindfulness and acceptance [PDF]

, 2014
Few research studies have explored how the level of a child's behavior problems leads to psychological distress in parents of children with autism. The authors explored whether psychological acceptance and mindfulness mediated this relationship between ...
Totsika, Vasiliki, Jones, Leah, Hastings, Richard P., Keane, Lisa, Rhule, Neisha, Hastings, Richard Patrick; id_orcid   +5 more
core   +1 more source

A phenomenological cartography of misophonia and other forms of sound intolerance

iScience, 2023
Summary: People with misophonia have strong aversive reactions to specific “trigger” sounds. Here we challenge this key idea of specificity. Machine learning was used to identify a misophonic profile from a multivariate sound-response pattern. Misophonia
Nora Andermane, Mathilde Bauer, Ediz Sohoglu, Julia Simner, Jamie Ward   +4 more
doaj   +1 more source

Autistic phenomenology: past, present, and potential future

Frontiers in Psychology, 2023
We are now at a transition point in autism conceptualisation, science, and clinical practise, where phenomenology could play a key role. This paper takes a broad view of the history of phenomenological perspectives on the autism concept and how this has ...
Jonathan Green, Nicola Shaughnessy
doaj   +1 more source

Language in autism and specific language impairment: Where are the links? [PDF]

, 2008
It has been suggested that language impairment in autism is behaviourally, neurobiologically, and etiologically related to specific language impairment (SLI).
Williams, David M., Botting, N., Williams, D., Boucher, J., Botting, Nicola, Boucher, Jill   +5 more
core   +1 more source

Links between looking and speaking in autism and first-degree relatives: insights into the expression of genetic liability to autism

Molecular Autism, 2018
Background Rapid automatized naming (RAN; naming of familiar items presented in an array) is a task that taps fundamental neurocognitive processes that are affected in a number of complex psychiatric conditions.
Kritika Nayar, Peter C Gordon, Gary E Martin, Abigail L Hogan, Chelsea La Valle, Walker McKinney, Michelle Lee, Elizabeth S Norton, Molly Losh   +8 more
doaj   +1 more source

Autism as a disorder of neural information processing: directions for research and targets for therapy [PDF]

, 2004
The broad variation in phenotypes and severities within autism spectrum disorders suggests the involvement of multiple predisposing factors, interacting in complex ways with normal developmental courses and gradients. Identification of these factors, and
Greenough, WT, Powell, SB, Rubenstein, JLR, Beckel-Mitchener, A, Anderson, GM, DeLorey, TM, Jiang, YH, Belmonte, MK, Boulanger, LM, Levitt, PR, Tierney, E, Courchesne, E, Cook, EH, Perry, EK   +13 more
core   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder. [PDF]

PLoS ONE, 2015
Autism spectrum disorder comprises several neurodevelopmental conditions presenting symptoms in social communication and restricted, repetitive behaviors.
Daniela Brunner, Patricia Kabitzke, Dansha He, Kimberly Cox, Lucinda Thiede, Taleen Hanania, Emily Sabath, Vadim Alexandrov, Michael Saxe, Elior Peles, Alea Mills, Will Spooren, Anirvan Ghosh, Pamela Feliciano, Marta Benedetti, Alice Luo Clayton, Barbara Biemans   +16 more
doaj   +1 more source

Context effects: discourse structure influences narrative ability in autism and first-degree relatives

Frontiers in Psychiatry
IntroductionNarrative, or storytelling, ability is a well-documented area of difficulty in autism spectrum disorder (ASD) and is an important skill that is related to social-communicative success.
Emily Landau, Kritika Nayar, Kritika Nayar, Gary E. Martin, Cassandra Stevens, Cassandra Stevens, Jiayin Xing, Jiayin Xing, Janna Guilfoyle, Joseph C. Y. Lau, Molly Losh   +10 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source