Results 191 to 200 of about 39,488 (289)
Mechanistic trials, therapy and developmental science—An exemplar from early autism care
Abstract Background Mechanistic design and analysis in clinical trials remains relatively rare in child mental health and autism, despite the considerable value that it could have in developing therapy practice and in illuminating basic science. Clinical trials themselves continue to have insufficient influence on actual clinical practice in child ...
Jonathan Green
wiley +1 more source
Broad autism phenotype features of Chinese parents with autistic children and their associations with severity of social impairment in probands. [PDF]
Shi LJ +8 more
europepmc +1 more source
Psychopathy traits and their link to emotion recognition impairments in conduct disorder
Abstract Background Neurocognitive models suggest that callous‐unemotional (CU) traits in youths with conduct disorder (CD) are linked to emotion recognition impairments, particularly in identifying distress emotions like fear and sadness. However, CD may be accompanied by grandiose‐manipulative (GM) and/or impulsive‐irresponsible (II) traits in ...
Gregor Kohls +9 more
wiley +1 more source
Abstract Background People with neurodevelopmental and mental health conditions have been demonstrated to have elevated rates of sensory processing (SP) difficulties in research and practice but the temporal order of this relationship is unclear. Methods This study sought to investigate whether SP difficulties in infancy predicted mental health at 5 ...
Emma Butler +2 more
wiley +1 more source
Reward processing in children with affective dysregulation
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner +11 more
wiley +1 more source
Abstract Background Sleep disturbances are widely considered to be a transdiagnostic feature of common behavioural and emotional difficulties in childhood, yet most studies treat sleep as a single construct. Where studies have explored specific sleep problems to psychopathology in children, these tend to only include behavioural or emotional ...
Alina A. Marinca +4 more
wiley +1 more source
Abstract Background Sex differences in the clinical presentation of autism are established, but evidence on early‐life co‐occurring physical illnesses in early‐diagnosed autistic individuals is scarce. This nationwide cohort study examined sex‐stratified incidence of physical illnesses within 5 years after autism spectrum disorder (ASD) diagnosis in ...
Yu‐Chieh Chuang +6 more
wiley +1 more source
Diminished social reward anticipation in the broad autism phenotype as revealed by event-related brain potentials. [PDF]
Cox A +7 more
europepmc +1 more source
Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes +6 more
wiley +1 more source
International Registry of NKX2‐1‐Related Disorders: Clinical, Genetic, and Imaging Perspectives
Abstract Background NKX2‐1–related disorders result from heterozygous variants in NKX2‐1, a gene crucial for brain, lung, and thyroid development. Although movement disorders, hypothyroidism, and neonatal respiratory distress are recognized, the full phenotype and genotype–phenotype relationships remain incompletely defined.
Laia Nou‐Fontanet +47 more
wiley +1 more source

