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Pulmonary aspergillosis in a horse: a case report. [PDF]

Braz J Vet Med
Melo UP, Ferreira C, Barreto SWM.
europepmc   +1 more source

Effects of diethylene glycol contamination of pharmaceutical products on unexplained acute kidney injury in children: a systematic review. [PDF]

Clin Exp Pediatr
Soleman SR, Adnan ML, Sudiarto HA, Mahathma SB, Tazkia AA, Firdaus HA, Khotijah AA, Pramaningtyas MD, Choironi EA.   +8 more
europepmc   +1 more source

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Simultaneous analysis of oxytetracycline hydrochloride, lidocaine, and bromhexine hydrochloride in the presence of many interfering excipients

Archiv Der Pharmazie, 2021
AbstractA gradient elution high‐performance liquid chromatographic method with a diode array detector is introduced for the first time for the simultaneous estimation of three drugs, namely, oxytetracycline hydrochloride (OXT), lidocaine (LDC), and bromhexine hydrochloride (BRH), in a veterinary formulation (OxyClear® solution) that contains many ...
Mohammed Gamal, Ibrahim A Naguib, Rehab Abdelfatah   +2 more
exaly   +3 more sources

Elemental impurities determination in bromhexine hydrochloride injections

Journal of Pharmaceutical and Biomedical Analysis, 2023
Elemental impurities in drug products have no therapeutic effect and may pose toxicological concerns, therefore it is urgent to assess the safety of elements especially in parenteral exposure drug. In the present work, a high throughput inductively coupled plasma mass spectrometry (ICP-MS) method was developed for the quantitative determination of 31 ...
Shujuan, Xu, Lei, Zhang, Qingshan, Bai, Lihua, Wang, Xiao, Chen   +4 more
exaly   +3 more sources

Facile approaches for determination of Bromhexine Hydrochloride and its active metabolite Ambroxol Hydrochloride using Eosin Y

Annales Pharmaceutiques Francaises, 2022
New validated Spectroscopic methods were developed to assay Bromhexine Hydrochloride and its active metabolite Ambroxol Hydrochloride separately in pure form and pharmaceutical formulations. The spectrophotometric assay (method I) shows complex formation between each of the drugs and Eosin Y at 540nm at pH 3.6 and 3.4mL of 4×10-4M Eosin for Bromhexine ...
Manal Eid, Shereen Shalan, Heba Elmansi   +2 more
exaly   +3 more sources

In Vitro Inhibition of SARS-CoV-2 Infection by Bromhexine hydrochloride

, 2022
ABSTRACT The world is enduring the SARS CoV-2 pandemic, and although extensive research has been conducted on the issue, only a few antivirals have been approved to treat patients with COVID-19. Bromhexine hydrochloride was previously identified as a potent inhibitor of TMPRSS2, an essential protease for ACE-2 virus receptor ...
Ronaldo Martins, Iasmin Ferreira, Daniel M. M. Jorge, Leticia Almeida, Juliano P. Souza, Marjorie Pontelli, Italo A. Castro, Thais M. Lima, Rosa M. M. Viana, Dario Zamboni, Priscyla D. Marcato, Eurico Arruda   +11 more
openaire   +2 more sources

Chemiluminescence determination of bromhexine hydrochloride with morin as chemiluminescent reagent

Luminescence, 2008
AbstractA new chemiluminescence (CL) reaction was observed when cerium(IV) solution was injected into bromhexine hydrochloride–morin solution. Based on this, a flow‐injection CL method for the determination of bromhexine hydrochloride was established.
Qingqing, Jiang, Fei, Nie, Jiuru, Lu
exaly   +3 more sources

Direct Kinetic Determination of Bromhexine Hydrochloride in Pharmaceutical Formulations

Analytical Letters, 1993
Abstract A very simple, automatic, fast method for the photometric determination of bromhexine hydrochloride based on the application of kinetic methodology and the stopped-flow mixing technique to the coupling reaction between the diazotized bromhexine derivative and N-(1-naphthyl)ethylenediamine is proposed.
A Gómez-Hens, D Perez-Bendito
exaly   +2 more sources

Effect of Bromhexine Hydrochloride Therapy for Alcoholic Chronic Pancreatitis

Alcoholism: Clinical and Experimental Research, 2005
Abstract: Background: Abstinence is a prerequisite for the treatment of alcoholic chronic pancreatitis, but there are patients who have repeated attacks because of their inability to abstain and the consequent congestive effects of the continued alcohol intake on pancreatic juice.
Tatsuhiro, Tsujimoto, Takuya, Tsuruzono, Kazushige, Hoppo, Yoshinobu, Matsumura, Jyunichi, Yamao, Hiroshi, Fukui   +5 more
exaly   +3 more sources

TLC Densitometric Determination of Bromhexine Hydrochloride in Pharmaceuticals, and Its Validation

Journal of Liquid Chromatography and Related Technologies, 2004
Abstract A simple and rapid densitometric method has been developed for determination of bromhexine hydrochloride in pharmaceutical preparations. After dilution or extraction of the analyte using a mixture of acetone–water (2:1), the extracts were spotted on pre‐coated silica gel plates, which were then developed with a mixture of n‐butanol–glacial ...
Gunawan Indrayanto
exaly   +2 more sources