Results 101 to 110 of about 555 (124)
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Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2013
Simple, rapid, sensitive, precise and accurate spectrophotometeric methods for the determination of ephedrine hydrochloride (E-HCl) and bromhexine hydrochloride (Br-HCl) in bulk samples, dosage form and in spiked urine samples were investigated. The methods are based on the formation of a yellow colored ion-associates due to the interaction between the
N T Abdel-Ghani, M S Rizk
exaly +3 more sources
Simple, rapid, sensitive, precise and accurate spectrophotometeric methods for the determination of ephedrine hydrochloride (E-HCl) and bromhexine hydrochloride (Br-HCl) in bulk samples, dosage form and in spiked urine samples were investigated. The methods are based on the formation of a yellow colored ion-associates due to the interaction between the
N T Abdel-Ghani, M S Rizk
exaly +3 more sources
Smart Analytical Study Applied for Quantitative Analysis of Bromhexine Hydrochloride
Analytical Chemistry Letters, 2016AbstractDegradation study reported on bromhexine hydrochloride is very rare, in this article smart degradation study based on first step neutralization process have been developed for analysis of bromhexine hydrochloride in the presence of its oxidative degradation product.
Khalid Abdel-Salam M. Attia +2 more
exaly +2 more sources
Journal of Pharmaceutical and Biomedical Analysis
A long-term stability study using high performance liquid chromatography (HPLC) revealed an unidentified impurity in the bromhexine hydrochloride injection, which was employed as a mucolytic agent. Investigations into stress degradation and elemental impurities revealed one of the elemental impurities Fe3+ in this injection as the primary generator of ...
Min, Zhou +5 more
exaly +3 more sources
A long-term stability study using high performance liquid chromatography (HPLC) revealed an unidentified impurity in the bromhexine hydrochloride injection, which was employed as a mucolytic agent. Investigations into stress degradation and elemental impurities revealed one of the elemental impurities Fe3+ in this injection as the primary generator of ...
Min, Zhou +5 more
exaly +3 more sources
The effect of bromhexine hydrochloride on the viscoelastic properties of mucus from the mini-pig
European Respiratory Journal, 1990Mucus was collected daily from open-ended pouches established surgically in three mini-pigs. After a five day control period bromhexine hydrochloride (BHCl) was administered to each pig at dose levels of 0.5, 1.0 and 2.0 mg.kg-1 twice daily for five days.
G P, Martin, B E, Loveday, C, Marriott
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Journal of Pharmaceutical and Biomedical Analysis, 2008
A simple, sensitive and specific liquid chromatography-electrospray ionization-mass spectrometry method was developed for the quantitative determination of bromhexine in human plasma. Sample preparation involved simple liquid-liquid extraction. Simvastatin was used as internal standard.
Wen, Zhang, Fang, Feng, Ya, Wang
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A simple, sensitive and specific liquid chromatography-electrospray ionization-mass spectrometry method was developed for the quantitative determination of bromhexine in human plasma. Sample preparation involved simple liquid-liquid extraction. Simvastatin was used as internal standard.
Wen, Zhang, Fang, Feng, Ya, Wang
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Assessment of bromhexine hydrochloride formulations in human dry eye patients
Journal of Controlled Release, 1994Abstract The mucolytic drug bromhexine hydrochloride (BH), was formulated in different ohthalmic dosage forms. The influence of the drug from the different formulations on tear flow rate in humans was investigated. The formulations tested were: BH aqueous solution, methylcellulose and carbopol934 hydrogels; and two polymeric inserts, namely; Gantrez ...
Tahani H. El-Faham, Ali A. Massoud
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Bromhexine Hydrochloride Adsorption by Some Solid Excipients Used in the Formulation of Tablets
Drug Development and Industrial Pharmacy, 1988AbstractAdsorption isotherms of aqueous bromhexine hydrochloride (BHCI) were determined for activated charcoal, kaolin, elcema, avicel PH 101 and 102. The affinity of BHCI adsorption on charcoal was the highest followed by kaolin, avicel, elcema in a decreasing order. The pH alteration affected the adsorption on charcoal slightly.
M. A. Qtaitat +2 more
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The Analyst, 1987
Gas-liquid chromatographic (GLC) and high-performance liquid chromatographic (HPLC) methods were developed for the determination of pseudoephedrine hydrochloride and bromhexine hydrochloride in pharmaceuticals. A reversed-phase HPLC technique was used after ion pairing for separation in the HPLC method.
E V, Rao +3 more
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Gas-liquid chromatographic (GLC) and high-performance liquid chromatographic (HPLC) methods were developed for the determination of pseudoephedrine hydrochloride and bromhexine hydrochloride in pharmaceuticals. A reversed-phase HPLC technique was used after ion pairing for separation in the HPLC method.
E V, Rao +3 more
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INDIAN DRUGS, 2018
A simple, specific, accurate, precise and reproducible method has been developed and validated for the estimation of bromhexine hydrochloride and enrofloxacin in fixed dose combination using RP-HPLC. The separation was achieved using stationary phase ODS Hypersil C18 column (250 mm× 4.6 mm i.d.) in isocratic mode, with mobile phase containing 0.05 M ...
P Choksi +5 more
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A simple, specific, accurate, precise and reproducible method has been developed and validated for the estimation of bromhexine hydrochloride and enrofloxacin in fixed dose combination using RP-HPLC. The separation was achieved using stationary phase ODS Hypersil C18 column (250 mm× 4.6 mm i.d.) in isocratic mode, with mobile phase containing 0.05 M ...
P Choksi +5 more
openaire +1 more source
Clinical trial of a recent mucolytic agent bromhexine hydrochloride in sinusitis—A prospective study
Indian Journal of Otolaryngology, 1983Twentyfive adult patients with clinical and radiologial proof of sinusitis were treated with oral administration of Bromhexine tablets along with oral antibiotics, antihistamine and nasal decongestants and the outcome is evaluated.
T. M. Parameswaran +4 more
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