Results 51 to 60 of about 43,175 (307)
Molecules, 2010 A practical synthetic route for the preparation of 2-pyridyl and 3-pyridyl derivatives has been accomplished by utilizing a simple coupling reaction of stable 2-pyridylzinc bromides and 3-pyridylzinc bromides.
Reuben D. Rieke, Seung-Hoi Kim
doaj +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
The self-trapped hole in caesium halides [PDF]
, 1977 The equilibrium lattice configuration, electronic excitation energies and activation energies for hopping motion are calculated for a self-trapped hole in simple cubic CsCl, CsBr and CsI.
MONNIER, R, SONG, KS, STONEHAM, AM
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Química Nova, 2009 Pyrazinoic acid esters have been synthesized as prodrugs of pyrazinoic acid. In the literature, its preparation is reported through the reaction of pyrazinoyl chloride with alcohols and the reaction with DCC/DMAP.
João Paulo dos Santos Fernandes +1 more
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Ultrasonic and Densitometric Characterization of Hyaluronan and its Interaction with Surfactant [PDF]
, 2014 This disertation thesis is focused on the study of physico-chemical interactions of hyaluronan (with molecular weights from 10 to 1750 kDa) with cationic surfactants measured using uncommon technique named high resolution ultrasonic spectroscopy ...
Hurčíková, Andrea
core
2,4,6-Trimethylanilinium bromide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 In the title compound, C(9)H(14)N(+)·Br(-), an intra-molecular N-H⋯Br inter-action links the anion to the cation. In the crystal structure, inter-molecular N-H⋯Br inter-actions link the mol-ecules into a three-dimensional network.
Li-Jing Cui, Hai-Jun Xu
openaire +3 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
One-pot near-ambient temperature syntheses of aryl(difluoroenol) derivatives from trifluoroethanol [PDF]
, 2011 Difluoroalkenylzinc reagents prepared from 1-(2’-methoxy-ethoxymethoxy)-2,2,2-trifluoroethane and 1-(N,N-diethylcarbamoyloxy)-2,2,2-trifluoroethane at ice bath temperatures, underwent Negishi coupling with a range of aryl halides in a convenient one pot ...
Kyne, Sara H +4 more
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source