Results 41 to 50 of about 43,175 (307)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Alkenylation and Allylation of Aldehydes by Using an Ni/Cr/TDAE Redox System [PDF]
, 2001 In 360 females, Bone mineral density (BMD) in lumbar vertebrae (L2-L4) was assessed by quantitative computed tomography (QCT), and the values obtained were compared with the frequency of vertebral transformation or fracture as assessed by lateral scan ...
Goto, Kentaro +4 more
core +1 more source
SolidsThe monoclinic rare-earth metal(III) bromide oxoarsenates(III) RE5Br3[AsO3]4 of the A-type (RE = La and Ce) crystallize in the space group C2/c with the lattice parameters a = 1834.67(9) pm, b = 553.41(3) pm, c = 1732.16(9) pm and β = 107.380(3)° for ...
Ralf J. C. Locke +4 more
doaj +1 more source
Facile synthesis of functionalized spiro[indoline-3,2'-oxiran]-2-ones by Darzens reaction
Beilstein Journal of Organic Chemistry, 2013 A series of functionalized spiro[indoline-3,2'-oxiran]-2-ones was efficiently synthesized by Darzens reaction of phenacyl bromides with isatins both with N-alkyl groups and without N-substituent in the presence of potassium carbonate as a base catalyst ...
Qin Fu, Chao-Guo Yan
doaj +1 more source
Molecules, 2014 An efficient and general copper-catalyzed Goldberg reaction at 90–110 °C between aryl bromides and amides providing the desired products in good to excellent yields has been developed using N,N-dimethylglycine as the ligand.
Liqin Jiang
doaj +1 more source
Nature Communications, 2022 Synthetic methodologies that enable the formation of C‒Si bonds in organic molecules are desirable. Here, the authors report the nickel-catalyzed reductive alkylsilylation of acrylonitrile with unactivated alkyl bromides and chlorosilanes.
Jinwei Sun +5 more
doaj +1 more source
2,6-Dimethylpyridinium bromide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 The asymmetric unit of the title salt, C(7)H(10)N(+)·Br(-), comprises two 2,6-dimethyl-pyridinium cations and two bromide anions. One cation and one anion are situated in general positions, while the other cation and the other anion lie on a crystallographic mirror plane parallel to (010).
Salim F. Haddad +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Structural factors controlling the transition between columnar hexagonal and helical mesophase in triphenylene liquid crystals. [PDF]
, 2001 A series of novel triphenylenes has been synthesised by a combination of palladium catalysed coupling, oxidative cyclisation, bromination and nucleophilic aromatic substitution.
Cammidge, Andrew N, Gopee, Hemant
core +1 more source