Pharmacokinetics of oral bromocriptine in postpartum patients
PregnancyIntroduction Cardiomyopathy is a leading cause of maternal morbidity and mortality. A prolactin fragment has been implicated in the pathogenesis, and preliminary data suggest that bromocriptine—a dopamine receptor agonist that inhibits prolactin ...
Rachel Sinkey +7 more
doaj +2 more sources
Bromocriptine and its Antipyretic Effect in Central Hyperthermia [PDF]
Galicia ClínicaCentral hyperthermia is marked by rapid onset of elevated temperatures, resistant to antibiotics and antipyretics. Diagnosis requires exclusion of infectious sources and identification of an underlying neurological condition.
Sérgio Costa Monteiro +3 more
doaj +2 more sources
Neuroleptic Malignant Syndrome on Chronic Trifluoperazine Therapy: A Diagnostic Dilemma. [PDF]
Clin Case RepABSTRACT Neuroleptic malignant syndrome (NMS) is a rare, life‐threatening reaction to antipsychotic medication. This report describes the case of a 62‐year‐old male with chronic trifluoperazine use who presented with fever, rigidity, and altered mental status.
Baral S, Bhattarai S, Joshi KC.
europepmc +2 more sources
Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine
iScience, 2022 Summary: Bromocriptine is approved as a diabetes therapy, yet its therapeutic mechanisms remain unclear. Though bromocriptine’s actions have been mainly attributed to the stimulation of brain dopamine D2 receptors (D2R), bromocriptine also targets the ...
Despoina Aslanoglou +14 more
doaj +1 more source
Study on Synergistic Effect of Bromocriptine and Sitagliptin in Streptozotocin-induced Diabetic Rats [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Diabetes mellitus is a potentially morbid condition with high prevalence worldwide. Restoration of euglycemia in type 2 diabetes mellitus is difficult to achieve due to its multifactorial pathogenesis and frequently requires multiple ...
Govindaraj Nileshraj +3 more
doaj +1 more source
Impact of Nano-Bromocriptine on Egg Production Performance and Prolactin Expression in Layers
Animals, 2021 The current study aimed to investigate the potential use of nano-bromocriptine in improving the laying performance of late laying hens by modulating the prolactin gene expression.
Ahmed Dawod +7 more
doaj +1 more source
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas
BMC Endocrine Disorders, 2021 Background Prolactinoma is a functional pituitary adenoma that secretes excessive prolactin. Dopamine agonists (DAs) such as bromocriptine (BRC) are the first-line treatment for prolactinomas, but the resistance rate is increasing year by year, creating ...
Shuman Wang +6 more
doaj +1 more source
Bromocriptine monotherapy overcomes prostate cancer chemoresistance in preclinical models
Translational Oncology, 2023 Chemoresistance is a major obstacle in the clinical management of metastatic, castration-resistant prostate cancer (PCa). It is imperative to develop novel strategies to overcome chemoresistance and improve clinical outcomes in patients who have failed ...
Lijuan Bai +15 more
doaj +1 more source
Bromocriptine inhibits proliferation in the endometrium from women with adenomyosis
Frontiers in Endocrinology, 2023 ObjectiveBromocriptine treatment has been shown to reduce menstrual bleeding and pain in women with adenomyosis in a pilot clinical trial. The underlying mechanism contributing to the treatment effect is however unknown.
Yiqun Tang +9 more
doaj +1 more source
Bromocriptine in Rheumatic Diseases: A Review. [PDF]
Eur J RheumatolFreire de Carvalho J +1 more
europepmc +2 more sources