Results 121 to 130 of about 619,857 (348)

IMMUNOLOGICAL MARKERS OF UNCONTROLLED ATOPIC BRONCHIAL ASTHMA IN CHILDREN

open access: yesМедицинская иммунология, 2017
Bronchial asthma is a prevalent chronic allergic disease of lungs at early ages. A priority  task in allergology  is to search  biological  markers  related  to uncontrolled atopic  bronchial asthma.
M. V. Smolnikova   +3 more
doaj   +1 more source

Tensin1 expression and function in chronic obstructive pulmonary disease [PDF]

open access: yes, 2019
open access articleChronic obstructive pulmonary disease (COPD) constitutes a major cause of morbidity and mortality. Genome wide association studies have shown significant associations between airflow obstruction or COPD with a non-synonymous SNP in ...
Amrani, Y.   +7 more
core   +1 more source

Bronchial asthma and airway remodeling markers

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2013
Asthma is an inflammatory disease with extracellular matrix remodeling and collagen deposition. Vascular alterations have been suggested to contribute to airway hyper responsiveness.
S. Jehan, F. Mohamed, Jehane Osman
doaj   +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

open access: yesAllergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan   +29 more
wiley   +1 more source

Expression of VPAC1 in a murine model of allergic asthma [PDF]

open access: yes, 2013
Vasoactive intestinal polypeptide (VIP) is a putative neurotransmitter of the inhibitory non-adrenergic non-cholinergic nervous system and influences the mammalian airway function in various ways.
Braun, Armin   +4 more
core  

A new role for exhaled nitric oxide as a functional marker of peripheral airway caliber changes: a theoretical study

open access: yes, 2017
Though considered as an inflammation marker, exhaled nitric oxide (FENO) was shown to be sensitive to airway caliber changes to such an extent that it might be considered as a marker of them. It is thus important to understand how these changes and their
Haut, Benoît   +2 more
core   +2 more sources

COVID-19 in children with bronchial asthma: aspects of comorbidity

open access: yesДетские инфекции (Москва)
Relevance: to date, there is no single view on how COVID-19 proceeds in children with bronchial asthma. At the same time, bronchial asthma is observed in 14% of children in the population and their number continues to increase.
S. G. Gorbunov, A. V. Bitsueva
doaj   +1 more source

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

open access: yesAllergy, EarlyView.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang   +13 more
wiley   +1 more source

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