Abstract Background Forced expiratory volume in 1 s (FEV1) obtained using different types of laboratory spirometers and handheld microspirometers is often used interchangeably in research, despite substantial differences between devices. The aim of this study was to assess device‐related differences and the interchangeability of FEV1 measurements among
Leon L. Csonka +3 more
wiley +1 more source
Echocardiographic evaluations of right ventricular functions and dimensions in children with bronchial asthma in Ile-Ife, Nigeria. [PDF]
Adetola HH +5 more
europepmc +1 more source
Combined Pulmonary Fibrosis and Emphysema: Current Status and Future Perspective
This review summarizes recent advances in combined pulmonary fibrosis and emphysema (CPFE), proposing a novel etiologic classification framework encompassing four subtypes. We integrate a diagnostic algorithm to guide precise management and highlight emerging artificial intelligence strategies for risk stratification and dynamic prognostic assessment ...
Qinyu Deng +5 more
wiley +1 more source
Astragalus polysaccharide mitigates the airway inflammation in bronchial asthma by regulating Hedgehog/NLRP3/GSDMD pathway. [PDF]
Yu L, Liu Z, Zhang R, Lai J.
europepmc +1 more source
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan +5 more
wiley +1 more source
Sex-Specific Differences in Gut Microbiota Composition in Adult Patients with Bronchial Asthma. [PDF]
Hirano C +11 more
europepmc +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
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Efficacy and immune-inflammatory modulation of combined glucocorticoid and anti-tuberculosis therapy in patients with bronchial asthma and pulmonary tuberculosis. [PDF]
Fang L, Liao X, Lin J.
europepmc +1 more source
The Cytokine Response of Circulating Immune Cells to Rhinovirus (RV‐A16) is Reduced in Severe Asthma
ABSTRACT Severe asthma patients (SA) are more susceptible to respiratory infections with human rhinoviruses (HRV) than healthy subjects (H), causing exacerbations. In response to HRV, circulating immune cells are recruited to and activated at the local sites of infection.
Kaschin Jamal Jameel +10 more
wiley +1 more source
Correlation analysis of the serum CCR5 and LXA4 levels with airway remodelling in bronchial asthma patients. [PDF]
Huang H, Luo R, Yang X, Wu Z, Ding Z.
europepmc +1 more source

