Successful steroid‐free remission of MPO‐ANCA‐negative eosinophilic granulomatosis with polyangiitis (EGPA). Due to concurrent poorly controlled diabetes, standard high‐dose glucocorticoids were avoided. Low‐dose mepolizumab (100 mg/month) monotherapy was initiated, resulting in rapid eosinophil reduction, resolution of pulmonary infiltrates, and ...
Suzuka Matsuoka +7 more
wiley +1 more source
Age-related differences in patient-reported quality of care among adult German patients with bronchial asthma: a cross-sectional study. [PDF]
Wank A +4 more
europepmc +1 more source
ABSTRACT Background As monoclonal antibodies have proven effective in managing recalcitrant chronic rhinosinusitis with nasal polyps (CRSwNP), the concept of disease remission is evolving, underscoring the need for a comprehensive, multimodal evaluation of disease burden over time.
Francesco Giombi +12 more
wiley +1 more source
Prevalence of Allergic Bronchopulmonary Aspergillosis in Bronchial Asthma Patients: A Retrospective Observational Study. [PDF]
Swain A.
europepmc +1 more source
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu +11 more
wiley +1 more source
Efficacy of spleen aminopeptide combined with budesonide nebulization in the treatment of pediatric bronchial asthma and its impact on immune function and inflammatory cytokines. [PDF]
He S, Ran N, Yang X, Zhu B, Zhou D.
europepmc +1 more source
Quantification of Age and Sex Ratio Differences between Trial and Target Population for New Drugs
Clinical trials are essential to understand the benefit‐harm profile of new drugs. Lack of adequate representation in age and sex ratio in clinical trials can result, for example, in higher side effects for underrepresented patients. We quantified differences in age and sex ratios between trial and target populations of new drugs approved by the FDA ...
Miquel Serra‐Burriel +2 more
wiley +1 more source
Alpha-1 Antitrypsin Deficiency and Bronchial Asthma: Current Challenges. [PDF]
Lopez-Campos JL +3 more
europepmc +1 more source
Wirsungocele as a Rare Cause of Recurrent Pancreatitis: Etiology and Therapeutic Insights
ABSTRACT Wirsungocele, a cystic dilation at the end of the main pancreatic duct, is associated with recurrent acute pancreatitis. A 52‐year‐old man presented to our hospital with recurrent epigastric pain over an 8‐month period with a history of multiple medical visits for the same complaint.
Sorano Ichiya +8 more
wiley +1 more source
Japanese Patients With Obesity-Related Bronchial Asthma May Benefit From Laparoscopic Sleeve Gastrectomy. [PDF]
Sumitani M +4 more
europepmc +1 more source

