Results 271 to 280 of about 223,616 (335)

Real‐Life Clinical Experience With SQ Grass, Tree, Ragweed, and House Dust Mite Sublingual Immunotherapy Tablets: A Review of Evidence From Non‐Interventional Studies

Allergy, EarlyView.
ABSTRACT This review evaluates data from > 12,000 children, adolescents and adults (≥ 4 years) in non‐interventional studies to assess the real‐life effectiveness and safety of SQ sublingual immunotherapy (SLIT)‐tablets for allergic rhinitis (AR).
Oliver Pfaar, Christer Janson, Andreas Horn, André C. Knulst, Pascal Demoly   +4 more
wiley   +1 more source

Case Report: <i>Aspergillus fumigatus</i>-associated plastic bronchitis in a pediatric patient with cystic fibrosis complicated by allergic bronchopulmonary aspergillosis. [PDF]

Front Pediatr
Liu F, Zhao L, Gao Y, Wang X, Zhang H.
europepmc   +1 more source

Mechanical ventilation in patients with chronic obstructive pulmonary disease and bronchial asthma

, 2015
SyedMoied Ahmed, Manazir Athar
openalex   +1 more source

Diversity and Dosage Determine the Efficacy of the Probiotic SYN‐53 in Allergic Rhinoconjunctivitis: A Randomized, Double‐Blind, Placebo‐Controlled Trial

Allergy, EarlyView.
The probiotic food supplement SYN‐53 has previously shown efficacy in managing allergic rhinoconjunctivitis (ARC), with its high bacterial diversity and dosage hypothesized as key drivers. This study on 166 subjects aimed to confirm this hypothesis by comparing the effects of SYN‐53, a low dose variant (SYN‐53‐LD), a low diversity variant (SYN‐4), and ...
Karl‐Christian Bergmann, Torsten Zuberbier   +1 more
wiley   +1 more source

Alarmin Levels and Gastroesophageal Reflux Disease in Children: Significant Elevation of Thymic Stromal Lymphopoietin. [PDF]

Pediatr Rep
Sobieska-Poszwa O, Suwała S, Mańkowska-Cyl A, Krogulska A.   +3 more
europepmc   +1 more source

Microenvironment‐Driven Mast Cell Plasticity: Insights From Cytokine‐Activated Gene Signatures in Skin and Respiratory Diseases

Allergy, EarlyView.
Primary peripheral blood‐derived human mast cells exposed to IFNγ, IL‐33, IL‐4 + IL‐13, or TGFβ develop distinct transcriptional signatures with unique functional changes including degranulation and cytokine/chemokine release. Machine learning‐defined minimal cytokine‐activated signatures (245 genes) successfully detect cytokine‐primed mast cells in ...
Chiara Tontini, Rajia Bahri, Andrew Higham, Dave Singh, Angela Simpson, Silvia Bulfone‐Paus   +5 more
wiley   +1 more source

DNA damage response and cell fate decisions across the lifespan: from fetal development to age-related respiratory diseases. [PDF]

Cell Biosci
Cui X, Wang Y, Fu J.
europepmc   +1 more source

Immune Training of the Interleukin 6 Gene in Airway Epithelial Cells is Central to Asthma Exacerbations

Allergy, EarlyView.
This study aims to investigate how immune activation influences the epigenetic regulation and expression of the Interleukin‐6 (IL‐6) gene during asthma exacerbations. By examining molecular mechanisms of immune training, we seek to elucidate how IL‐6‐driven inflammatory pathways contribute to airway dysfunction and worsening asthma symptoms.
Lars P. Lunding, Markus Weckmann, Ulrich M. Zissler, Constanze Jakwerth, Rebecca Bodenstein‐Sgró, Sina Webering, Christina Vock, Johanna C. Ehlers, Romina A. M. Fernandez Ceballos, Sai Sneha Priya Nemani, Karosham Diren Reddy, Brian George G. Oliver, Cornelis J. Vermeulen, Maarten van de Berge, Carole Ober, Axel Künstner, Hauke Busch, Inke König, Christoph Garbers, Carsten B. Schmidt‐Weber, Marcel F. Nold, Ali Önder Yildirim, Claudia A. Nold‐Petry, Zane Orinska, Thomas Bahmer, Jan Heyckendorf, Gesine Hansen, Erika von Mutius, Klaus F. Rabe, Anna‐Maria Dittrich, Bianca Schaub, Folke Brinkmann, Matthias V. Kopp, Michael Wegmann, The ALLIANCE Study Group as part of the German Centre for Lung Research (DZL)   +34 more
wiley   +1 more source

METTL3-driven m⁶A modification orchestrates mitophagy-dependent ferroptosis in PM2.5-induced lung injury. [PDF]

Front Immunol
Ran Q, Gao J, Li G, Wang J, Li X, Xiong A, Zhang Y, Xiong Y, He X.   +8 more
europepmc   +1 more source

Long‐Term, Real‐World Effectiveness of Allergen Immunotherapy in Children and Adolescents With Allergic Rhinitis and Asthma

Allergy, EarlyView.
Pre‐defined, propensity score–matched paediatric cohort from REACT evaluating the long‐term effectiveness of AIT in children with AR, with or without asthma. AIT‐treated children showed greater reductions in AR medication use, asthma medication use, severe asthma exacerbations, and new oral corticosteroid prescriptions versus controls over 9 years ...
Christian Woehlk, Thomas Stranzl, Marco Contoli, Nick Freemantle, Andreas Kallsoy Slaettanes, Julie Rask Larsen, Celeste Porsbjerg, Benedikt Fritzsching   +7 more
wiley   +1 more source