A new guinea pig model of allergic asthma was used to investigate the effects of low doses of the phosphodiesterase inhibitors, rolipram (phosphodiesterase IV selective), ORG 20241 (N-hydroxy-4-(3,4-dimethoxyphenyl)-thiazole-2-carboximidamide; dual ...
Santing, Ruud E. +14 more
core +1 more source
Eosinophil granule proteins and bronchial asthma
For over 100 years, the association of eosinophils with bronchial asthma has been known. Over the past 20 years, the proteins comprising the eosinophil granule have been isolated and characterized.
Gerald J Gleich
doaj +1 more source
Lung function tests and bronchial hyperreactivity in asthma [PDF]
Asthma is characterized by the development of reversible airway obstruction and the decline of pulmonary function test. Determination of baseline ventilatory parameters i.e. forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) with
Kaczanowska, Ewa +2 more
core
Linkage analysis of bronchial hyperreactivity and atopy with chromosome 11q13
There are two key clinical features of asthma: allergy and bronchial hyperreactivity (BHR). Some pedigree studies of atopy have indicated linkage with the high affinity IgE receptor (FcϵRI-β) gene on chromosome 11q13, but others failed to confirm this ...
Wong, Zilla Y.H. +7 more
core +1 more source
Can development of asthma and bronchial hyperreactivity be reduced by subcutaneous immunotherapy in adult patients with allergic rhinitis? [PDF]
Tepetam FM +4 more
europepmc +1 more source
EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma [PDF]
Chronic damage and repair of the bronchial epithelium are features of asthma. We have previously reported that ex vivo stimulation of normal bronchial epithelial cells with epidermal growth factor (EGF), a key factor of epithelial repair, enhances the ...
Donna E Davies +52 more
core +2 more sources
Allerjik rinit ile astma arasındaki bağlantı uzun zamandan beri bilinmektedir. Allerjik rinit astma gelişmeden önce var olabilir. Astma semptomlarına sahip olmayan allerjik rinitli hastalar bronş hiperreaktivitesine sahip olabilir.
Ali Kokuludağ +4 more
core
EFFECT OF INHALED HEPARIN ON METHACHOLINE-INDUCED BRONCHIAL HYPERREACTIVITY
Although heparin is used as an anticoagulant, its biologic function has remained unclear since the 1920s. Glycosaminoglycan heparin possesses multiple noncoagulant properties, including anti-inflammatory actions, and it is possible that heparin may ...
core +1 more source
Effects of Adherence to Once-Daily Treatment on Lung Function, Bronchial Hyperreactivity and Health Outcomes in Adolescents with Mild-to-Moderate Asthmoka: A Twelve-Month Survey. [PDF]
Dal Negro RW, Turco P.
europepmc +1 more source
3ronchial hyperreactivity in systemic sclerosis patients: influence of associated Sjogren's syndrome [PDF]
Objective-To determine the frequency and relative risk of bronchial hyperreactivity to methacholine in systemic sclerosis patients with or without ...
Francesco Trotta +4 more
core

