Results 71 to 80 of about 79,822 (211)

PHOSPHODIESTERASE INHIBITORS REDUCE BRONCHIAL HYPERREACTIVITY AND AIRWAY INFLAMMATION IN UNRESTRAINED GUINEA-PIGS

open access: yes, 1995
A new guinea pig model of allergic asthma was used to investigate the effects of low doses of the phosphodiesterase inhibitors, rolipram (phosphodiesterase IV selective), ORG 20241 (N-hydroxy-4-(3,4-dimethoxyphenyl)-thiazole-2-carboximidamide; dual ...
Santing, Ruud E.   +14 more
core   +1 more source

Eosinophil granule proteins and bronchial asthma

open access: yesAllergology International, 1996
For over 100 years, the association of eosinophils with bronchial asthma has been known. Over the past 20 years, the proteins comprising the eosinophil granule have been isolated and characterized.
Gerald J Gleich
doaj   +1 more source

Lung function tests and bronchial hyperreactivity in asthma [PDF]

open access: yes, 2009
Asthma is characterized by the development of reversible airway obstruction and the decline of pulmonary function test. Determination of baseline ventilatory parameters i.e. forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) with
Kaczanowska, Ewa   +2 more
core  

Linkage analysis of bronchial hyperreactivity and atopy with chromosome 11q13

open access: yes, 1997
There are two key clinical features of asthma: allergy and bronchial hyperreactivity (BHR). Some pedigree studies of atopy have indicated linkage with the high affinity IgE receptor (FcϵRI-β) gene on chromosome 11q13, but others failed to confirm this ...
Wong, Zilla Y.H.   +7 more
core   +1 more source

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma [PDF]

open access: yes, 2013
Chronic damage and repair of the bronchial epithelium are features of asthma. We have previously reported that ex vivo stimulation of normal bronchial epithelial cells with epidermal growth factor (EGF), a key factor of epithelial repair, enhances the ...
Donna E Davies   +52 more
core   +2 more sources

Nonspecific bronchial hyperreactivity in patients with allergic rhinitis and its relationship with serum eosinophilic cationic protein

open access: yes, 2000
Allerjik rinit ile astma arasındaki bağlantı uzun zamandan beri bilinmektedir. Allerjik rinit astma gelişmeden önce var olabilir. Astma semptomlarına sahip olmayan allerjik rinitli hastalar bronş hiperreaktivitesine sahip olabilir.
Ali Kokuludağ   +4 more
core  

EFFECT OF INHALED HEPARIN ON METHACHOLINE-INDUCED BRONCHIAL HYPERREACTIVITY

open access: yes, 1995
Although heparin is used as an anticoagulant, its biologic function has remained unclear since the 1920s. Glycosaminoglycan heparin possesses multiple noncoagulant properties, including anti-inflammatory actions, and it is possible that heparin may ...

core   +1 more source

3ronchial hyperreactivity in systemic sclerosis patients: influence of associated Sjogren's syndrome [PDF]

open access: yes, 1995
Objective-To determine the frequency and relative risk of bronchial hyperreactivity to methacholine in systemic sclerosis patients with or without ...
Francesco Trotta   +4 more
core  

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