Results 1 to 10 of about 26,256 (214)

Comparing the inhalation of methacholine chloride and methacholine for methacholine challenge testing [PDF]

European Journal of Medical Research
Background Bronchial challenge testing with methacholine was applied to evaluate and quantify bronchial hyperresponsiveness (BHR) in asthma patients.
Meiping Chen, Bin Shen, Peiling Feng, Yanping Wu, Gang Huang   +4 more
doaj   +2 more sources

Salbutamol Reversal of Methacholine Induced Bronchoconstriction: Vibrating Mesh Nebulizer versus Pressurized Metered Dose Inhaler [PDF]

Journal of Asthma and Allergy
Beth E Davis, Brianne S Philipenko, Donald W Cockcroft Division of Respirology and Sleep Medicine, Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaCorrespondence: Beth E Davis, Division of Respirology and Sleep Medicine,
Davis BE, Philipenko BS, Cockcroft DW
doaj   +2 more sources

Bronchodilator Response in Patients with Persistent Allergic Asthma Could Not Predict Airway Hyperresponsiveness [PDF]

Allergy, Asthma & Clinical Immunology, 2007
Anticholinergics, or specific antimuscarinic agents, by inhibition of muscarinic receptors cause bronchodilatation, which might correlate with activation of these receptors by the muscarinic agonist methacholine.
Petanjek Bojana B, Grle Sanja P, Pelicarić Dubravka, Vranković Dubravka   +3 more
doaj   +3 more sources

Correlation between tidal breathing pulmonary function, exhaled nitric oxide and airway hyperresponsiveness in children aged 0–3 years with suspected asthma [PDF]

Frontiers in Pediatrics
ObjectiveTo investigate the correlation between tidal breathing pulmonary function parameters combined with mixed exhaled gas nitric oxide values and the degree of airway hyperresponsiveness (AHR) in children aged 0–3 years with suspected asthma ...
Jiangjiao Qin, Jiangjiao Qin, Fangjun Liu, Fangjun Liu, Ting Wang, Ting Wang, Zhou Fu, Zhou Fu, Ying Lin, Ying Lin, Xia Wang, Xia Wang, Jing Zhao, Jing Zhao, Sha Liu, Sha Liu   +15 more
doaj   +2 more sources

Methacholine hyperresponsiveness in mice with house dust mite‐induced lung inflammation is not associated with excessive airway constriction ex vivo [PDF]

Experimental Physiology
The role of excessive airway constriction in the hyperresponsiveness to nebulized methacholine in mice with experimental asthma is still contentious.
Andrés Rojas‐Ruiz, Magali Boucher, Cyndi Henry, Louis Gélinas, Rosalie Packwood, Percival Graham, Jorge Soliz, Ynuk Bossé   +7 more
doaj   +2 more sources

Oscillometry with or without spirometry for methacholine testing [PDF]

Physiological Reports
Oscillometry is proposed as a complementary technique to spirometry for methacholine testing. Yet, before being prescribed in conjunction with spirometry, the extent by which the oscillometric readouts are influenced by spirometric maneuvers, especially ...
Cyndi Henry, Magali Boucher, Marie‐Ève Boulay, Andréanne Côté, Ynuk Bossé   +4 more
doaj   +2 more sources

Self-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammation. [PDF]

, 2013
Nanocarriers can deliver a wide variety of drugs, target them to sites of interest, and protect them from degradation and inactivation by the body. They have the capacity to improve drug action and decrease undesirable systemic effects.
Bratt, Jennifer M, Franzi, Lisa M, Kenyon, Nicholas J, Lam, Kit S, Lee, Joyce, Luo, Juntao, Zeki, Amir A   +6 more
core   +19 more sources

Evaluation of coagulation activation after Rhinovirus infection in patients with asthma and healthy control subjects: an observational study [PDF]

, 2014
Background Asthma exacerbations are frequently triggered by rhinovirus infections. Both asthma and respiratory tract infection can activate haemostasis. Therefore we hypothesized that experimental rhinovirus-16 infection and asthmatic airway inflammation
Bel, EHD, De Pol, MAV, Johnston, SL, Kamphuisen, PW, Lutter, R, Majoor, CJ, Meijers, JCM, Molenkamp, R, Nieuwland, R, Sterk, PJ, Van der Poll, T, Van der Sluijs, KF, Wolthers, KC   +12 more
core   +15 more sources

Malat1 deficiency prevents hypoxia-induced lung dysfunction by protecting the access to alveoli

Frontiers in Physiology, 2022
Hypoxia is common in lung diseases and a potent stimulator of the long non-coding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1). Herein, we investigated the impact of Malat1 on hypoxia-induced lung dysfunction in mice.
Sandrine Sallé-Lefort, Sandrine Sallé-Lefort, Stéphanie Miard, Cyndi Henry, Christian Arias-Reyes, Christian Arias-Reyes, François Marcouiller, Marie-Josée Beaulieu, Sophie Aubin, Ariane Lechasseur, Ariane Lechasseur, Éric Jubinville, Éric Jubinville, David Marsolais, David Marsolais, Mathieu C. Morissette, Mathieu C. Morissette, Vincent Joseph, Vincent Joseph, Jorge Soliz, Jorge Soliz, Ynuk Bossé, Ynuk Bossé, Frédéric Picard, Frédéric Picard   +24 more
doaj   +1 more source

Airway Hyperresponsiveness, but Not Bronchoalveolar Inflammatory Cytokines Profiles, Is Modified at the Subclinical Onset of Severe Equine Asthma

Animals, 2023
Airway hyperresponsiveness (AHR) and inflammation are both observed in human and equine asthma. The aim of this study was to assess the timeline and relationship of both features at the subclinical onset of severe equine asthma (SEA).
Thibault Frippiat, Tatiana Art, Irene Tosi   +2 more
doaj   +1 more source