Results 1 to 10 of about 88,868 (211)

Does bronchial hyperresponsiveness predict a diagnosis of cough variant asthma in adults with chronic cough: a cohort study [PDF]

open access: yesRespiratory Research, 2021
Bronchial hyperresponsiveness is a typical, but non-specific feature of cough variant asthma (CVA). This study aimed to determine whether bronchial hyperresponsiveness may be considered as a predictor of CVA in non-smoking adults with chronic cough (CC).
Aleksandra Rybka-Fraczek   +6 more
doaj   +2 more sources

RhoA, a Possible Target for Treatment of Airway Hyperresponsiveness in Bronchial Asthma

open access: yesJournal of Pharmacological Sciences, 2010
.: Airway hyperresponsiveness to nonspecific stimuli is one of the characteristic features of allergic bronchial asthma. An elevated contractility of bronchial smooth muscle has been considered as one of the causes of the airway hyperresponsiveness.
Yoshihiko Chiba, Miwa Misawa
exaly   +3 more sources

Glucocorticoids Ameliorate Antigen-Induced Bronchial Smooth Muscle Hyperresponsiveness by Inhibiting Upregulation of RhoA in Rats

open access: yesJournal of Pharmacological Sciences, 2008
To determine the mechanism(s) of the inhibitory effect of glucocorticoids on airway hyperresponsiveness in allergic bronchial asthma, the effects of systemic treatment with glucocorticoids on bronchial smooth muscle hyperresponsiveness and RhoA ...
Yoshihiko Chiba   +4 more
doaj   +2 more sources

Role of Rac1 in augmented endothelin-1-induced bronchial contraction in airway hyperresponsive mice

open access: yesJournal of Pharmacological Sciences, 2019
It has recently been exhibited that Rac1 expression is increased in the bronchial tissue of a murine model with repeated antigen-challenged airway hyperresponsiveness (AHR).
Yuki Kai   +5 more
doaj   +2 more sources

Bronchial hyperresponsiveness [PDF]

open access: yesOccupational Medicine, 2015
Bronchial hyperresponsiveness (BHR) is often regarded as a 'hallmark' of asthma and bronchoprovocation testing is frequently performed to support a diagnosis of asthma. However, BHR is also found in a spectrum of other lung diseases and can be provoked by a variety of specific stimuli.To review the pathophysiology of BHR, discuss various methods of ...
J, Borak, R Y, Lefkowitz
openaire   +2 more sources

Mannitol Challenge to Assess Therapy Response in Asthmatic Children: An Interventional Cohort Study

open access: yesChildren, 2023
Bronchial provocation tests, such as the mannitol challenge, can be performed to identify and quantify the severity of bronchial hyperresponsiveness in asthmatic patients.
Nikolaos Karantaglis   +6 more
doaj   +1 more source

Airway hyperresponsiveness in bronchial asthma: pathogenesis basics

open access: yesБюллетень сибирской медицины, 2002
Bronchial asthma has three main components: persistent bronchial inflammation, reversible bronchial obstruction and bronchial hyperresponsiveness to nonspecific triggers. Airway hyperresponsiveness is a complex phenomenon that develops upon the influence
I. A. Deyev   +4 more
doaj   +1 more source

The usefulness of bronchial challenge tests in the diagnosis of occupational asthma

open access: yesMedycyna Pracy, 2018
Bronchial hyperresponsiveness (BHR) is the individual ability to respond with bronchoconstriction to a variety of specific and nonspecific stimuli which do not cause these symptoms among healthy subjects.
Ewa Nowakowska-Świrta   +2 more
doaj   +1 more source

Challenging case of severe acute asthma in a mechanically ventilated patient managed with sevoflurane

open access: yesClinical Case Reports, 2023
Acute severe bronchial asthma is a chronic inflammatory disease characterized by hyperresponsiveness of the airways leading to bronchoconstriction. We present a case of refractory life‐threatening bronchial asthma that was managed with sevoflurane gas ...
Satheesh Munusamy   +3 more
doaj   +1 more source

Special Issue on ‘Asthma and Allergic Inflammation’

open access: yesVaccines, 2023
Asthma is a chronic inflammatory airway disease, driven by either allergic or non-allergic stimuli, which usually manifests as wheezing, reversible airflow limitation, and bronchial hyperresponsiveness [...]
Corrado Pelaia
doaj   +1 more source

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