Results 41 to 50 of about 88,868 (211)

Early Growth Response 1‐Associated Epithelial Autophagy‐Related Changes in Allergic Airway Inflammation

open access: yesPediatric Discovery, EarlyView.
House dust mite (HDM) exposure induces early growth response 1 (EGR1) expression in airway epithelial cells and is accompanied by autophagy‐associated alterations, including increased LC3B‐II and Vps34 levels and decreased p62 abundance. Manipulation of EGR1 expression modulates these autophagy‐related changes, whereas pharmacological inhibition of ...
Xinyang Wang   +3 more
wiley   +1 more source

Bronchial provocation tests in clinical practice

open access: yesSão Paulo Medical Journal
Bronchial hyperresponsiveness, which consists of an exaggerated response of the airways to bronchoconstrictor stimuli, is one of the main characteristics of asthma, presented in nearly all asthmatic patients.
Marcos de Carvalho Borges   +2 more
doaj   +1 more source

The effect of immunotherapy on nonspecific bronchial hyperresponsiveness in bronchial asthma and allergic rhinitis

open access: yes, 2001
Allergen injection therapy may improve nonallergic bronchial hyperresponsiveness, but results at the moment are less than convincing. The present study was conducted to evaluate the effect of immunotherapy on the degree of nonspecific bronchial ...
장준
core   +1 more source

Increased frequency of bronchial hyperresponsiveness in patients with inflammatory bowel disease. [PDF]

open access: yes, 1995
peer reviewedAlthough bronchopulmonary manifestations are rare in inflammatory bowel disease (IBD), subclinical abnormalities have been described in up to 50% of cases. The pathophysiology of these abnormalities remains unknown.
Radermecker, Maurice   +6 more
core   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit   +5 more
wiley   +1 more source

Advances in Light-Responsive Smart Multifunctional Nanofibers: Implications for Targeted Drug Delivery and Cancer Therapy

open access: yesPharmaceutics
Over the last decade, scientists have shifted their focus to the development of smart carriers for the delivery of chemotherapeutics in order to overcome the problems associated with traditional chemotherapy, such as poor aqueous solubility and ...
Ahmed M. Agiba   +10 more
doaj   +1 more source

Bronchial hyperresponsiveness in children with atopic rhinitis: a 7-year follow-up [PDF]

open access: yes, 2004
A high prevalence of bronchial hyperresponsiveness (BHR) was found in atopic subjects with rhinitis. Those subjects may be at higher risk for developing bronchial asthma.
Pajno, G   +16 more
core   +1 more source

Asthma Remission From Childhood to Young Adulthood–A Population‐Based Cohort Study

open access: yesAllergy, EarlyView.
Among 257 participants with asthma at age 8 years, 39% achieved symptom‐based remission by age 24, 29% achieved clinical remission, and 18% achieved complete remission. Male sex increased the likelihood of symptom‐based remission, while food sensitization and overweight/obesity decreased the likelihood.
Lina Broström   +6 more
wiley   +1 more source

Pulmonary adaptation to repeated poly(I:C) exposure is impaired in asthmatic mice: an observational study

open access: yesRespiratory Research
Background While asthma exacerbations remain a major challenge in patient management, few animal models exist to explore the underlying mechanisms. Here, we established an animal model of asthma that can be used to study pathophysiological mechanisms and
Benoit Allard   +7 more
doaj   +1 more source

Short-term effects of budesonide, nedocromil sodium and salmeterol on bronchial hyperresponsiveness in childhood asthma

open access: yes, 1998
Background: The effects of budesonide, nedocromil sodium and salmeterol on bronchial hyperresponsiveness were determined over a period of 3 ...
BAKI, A, Karaguzel, GÜLAY
core   +1 more source

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