Airway hyperresponsiveness, a key feature of asthma, is associated with exercise-induced asthma. Tezepelumab was reported to reduce airway hyperresponsiveness.
Yoshiro Kai, MD, PhD, Yuichi Hishida, RT
doaj +1 more source
BackgroundThe interrelation between airway inflammation, bronchial hyperresponsiveness (BHR) and atopy remains ...
Topal, E. +7 more
core +1 more source
The Endogenous Th17 Response in NO
Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
Suratt, Benjamin T. +45 more
core +2 more sources
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe +24 more
wiley +1 more source
Food, Fatty Acids and Antioxidants Intake and their Associations with Atopic disease in Adults [PDF]
It was hypothesized that high fat consumption, specifically from polyunsaturated fatty acids, may be positively related to atopic disease prevalence.
Trak-Fellermeier, María Angélica
core +1 more source
Effect of inhaling eosinophils on bronchial hyperresponsiveness and bronchial ciliary beats in bronchial asthma : Induction of dual asthmatic responses by inhalation of eosinophils [PDF]
Eosinophils are considered to be related to the pathogenesis of bronchial asthma in the inflammatory reaction. To extend our understanding of eosinophils in relation to bronchial hyperresponsiveness as well as bronchial mucosal damage, we examined the ...
山本, 高宏, Yamamoto, Takahiro
core +1 more source
The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith +9 more
wiley +1 more source
Content of Th17 related and Th2 cytokines in asthma patients with cold airway hyperresponsiveness
The phenomenon of cold airway hyperresponsiveness is rather common among patients with bronchial asthma. Possible participation of immune mechanisms in its occurence is scarcely studied.
A. B. Pirogov +5 more
doaj +1 more source
Airways Hyperresponsiveness and Atopy: A Comparison of Inuit and Montreal Schoolchildren
OBJECTIVE: To compare the prevalence ol exercise induced bronchial hyperresponsiveness in Inuit children with that or children in Montreal, and to identify possible genetic and environmental determinants of the differences observed.
Brenda Hemmelgarn +4 more
doaj +1 more source
Sodium intake and bronchial hyperresponsiveness in adults [PDF]
Several investigations suggested a relationship between sodium intake and asthma and bronchial hyperresponsiveness (BHR), respectively. However, clinical and epidemiological studies did not show consistent finding.We analysed the association between dietary sodium intake and BHR to methacholine among 613 adults aged 20-65 years as one of the two German
Sausenthaler, Stefanie +4 more
openaire +3 more sources

