Results 51 to 60 of about 28,269 (237)

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang, Hai Wang, Yong‐Zheng Zhang, Yan‐Yan Chen, Xin‐Xin Xing, Yi‐Cheng Ding   +5 more
wiley   +1 more source

Ia型(単純気管支れん縮型)喘息における気道過敏性について…年齢および気管支肺胞洗浄液中の細胞成分との関連について [PDF]

, 1996
Bronchial hyperresponsiveness was examined in relation to age, ventilatory function, and the proportion of bronchoalveolar lavage (BAL) cells in 39 patients with type Ia asthma (simple bronchoconstriction) (25 with type Ia-1 and 14 with type Ia-2 ...
Ashida, Kozo, Harada, Hideo, Hosaki, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Nawa, Yuichiro, Ochi, Koji, Takeuchi, Kazuaki, Tanizaki, Yoshiro, Tsugeno, Hirofumi, Yokota, Satoshi   +10 more
core   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Updating the concept of asthma. Is asthma a syndrome?

Revista Alergia México, 2015
Several symptoms are common to different processes that affect the respiratory system and their precise assessment is key to a correct diagnosis. Amongst those symptoms, mostly dyspnoea oriented toward the possible diagnosis of asthma.
Francisco Muñoz-López
doaj   +1 more source

Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma. [PDF]

, 2019
Asthma is a common disorder of the airways characterized by airway inflammation and by decline in lung function and airway remodeling in a subset of asthmatics.
Broide, David H, Hur, Gyu Young
core  

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Bronchial provocation tests in clinical practice

São Paulo Medical Journal
Bronchial hyperresponsiveness, which consists of an exaggerated response of the airways to bronchoconstrictor stimuli, is one of the main characteristics of asthma, presented in nearly all asthmatic patients.
Marcos de Carvalho Borges, Erica Ferraz, Elcio Oliveira Vianna   +2 more
doaj   +1 more source

Vocal cord dysfunction and lyrangeal hyper-responsiveness: a function of altered autonomic balance? [PDF]

, 2002
The interrelationships between vocal cord dysfunction and laryngeal hyperresponsiveness may have profound implications in the diagnosis and management of patients with difficult respiratory ...
Ayers, J.G., Gabbott, P.L.G.
core  

長期間の喫煙は高齢者気管支喘息における気道過敏性と関連した白血球LTB4産生を亢進させる [PDF]

, 2004
: Influence of cigarette smoking on leukotriene 84 (LTB4) generation by leucocytes associated with bronchial hyperresponsiveness was examined in 110 patients with asthma. l.
Ashida, Kozo, Fujii, Makoto, Hamada, Masanori, Hosaki, Yasuhiro, Iwagaki, Naofumi, Mitsunobu, Fumihiro, Nagata, Takuya, Takata, Shingo, Tanizaki, Yoshiro, Yokoi, Tadashi   +9 more
core   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, EarlyView.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source