Results 71 to 80 of about 28,269 (237)

Diagnosis and management of eosinophilic asthma: a US perspective. [PDF]

, 2014
Eosinophilic asthma is now recognized as an important subphenotype of asthma based on the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be associated with increased asthma severity, atopy, late-onset disease, and ...
Doherty, Taylor A, Walford, Hannah H
core   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Content of Th17 related and Th2 cytokines in asthma patients with cold airway hyperresponsiveness

Медицинская иммунология
The phenomenon of cold airway hyperresponsiveness is rather common among patients with bronchial asthma. Possible participation of immune mechanisms in its occurence is scarcely studied.
A. B. Pirogov, A. G. Prikhodko, N. A. Pirogova, D. E. Naumov, D. A. Gassan, J. M. Perelman   +5 more
doaj   +1 more source

Ultra‐Processed Food Consumption and Childhood Allergic Diseases: Increased Risk of Asthma Onset in the SENDO Project

Allergy, EarlyView.
The SENDO cohort study (2015–2024) prospectively analyzed the impact of ultra‐processed food (UPF) consumption on asthma and atopy in 1,546 Spanish children. Higher UPF intake (NOVA 4 classification) was significantly associated with an increased risk of asthma but not atopy, atopic dermatitis, neumoallergen sensitation, food allergy over five years ...
O. Galindo, M. J. Goikoetxea, L. Moreno‐Galarraga, L. Argiz, J. M. Moreno‐Villares, Victor de la O, N. Martín‐Calvo   +6 more
wiley   +1 more source

Airways Hyperresponsiveness and Atopy: A Comparison of Inuit and Montreal Schoolchildren

Canadian Respiratory Journal, 1995
OBJECTIVE: To compare the prevalence ol exercise induced bronchial hyperresponsiveness in Inuit children with that or children in Montreal, and to identify possible genetic and environmental determinants of the differences observed.
Brenda Hemmelgarn, Esther Loozen, Sheila Saralegui, Susan Chatwood, Pierre Ernst   +4 more
doaj   +1 more source

Management of acute bronchitis in healthy adults. [PDF]

, 2004
Acute respiratory infections (ARIs) are the most common infections in humans, accounting for half of all acute conditions each year in the United States. Acute bronchitis episodes represent a significant portion of these illnesses.
Aagaard, Eva, Gonzales, Ralph
core  

MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation

Allergy, EarlyView.
In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata, Jaclyn W. McAlees, Julie M. Hargis, Archana Shankar, Shouxiong Huang, Senad Divanovic, Ian P. Lewkowich   +6 more
wiley   +1 more source

Inflammatory Airway Disease of Horses - Revised Consensus Statement [PDF]

, 2016
The purpose of this manuscript is to revise and update the previous consensus statement on inflammatory airway disease (IAD) in horses. Since 2007, a large number of scientific articles have been published on the topic and these new findings have led to ...
Cardwell, J M, Couetil, L L, Gerber, V, Lavoie, J P, Leguillette, R, Richard, E A   +5 more
core   +5 more sources

Acetylcholine-treated murine dendritic cells promote inflammatory lung injury [PDF]

, 2019
In recent years a non-neuronal cholinergic system has been described in immune cells, which is often usually activated during the course of inflammatory processes. To date, it is known that Acetylcholine (ACh), a neurotransmitter extensively expressed in
Alcain, Julieta María, Candolfi, Marianela, Geffner, Jorge Raúl, Gori, María Soledad, Jancic, Carolina Cristina, Moreno Ayala, Mariela Alejandra, Salamone, Gabriela Veronica, Vanzulli, Silvia, Vermeulen, Elba Monica   +8 more
core   +1 more source

Bronchial responses to substance P after antigen challenge in the guinea-pig: in vivo and in vitro studies

Mediators of Inflammation, 1992
The effect of antigen challenge on the airway responses to substance P and on the epithelial neutral endopeptidase (NEP) activity was investigated in aerosol sensitized guinea-pigs.
E. Boichot, V. Lagente, G. Le Gall, C. Carré, J. M. Mencia-Huerta, P. Braquet, A. Lockhart, N. Frossard   +7 more
doaj   +1 more source