Results 81 to 90 of about 28,269 (237)

BMI can influence adult males' and females' airway hyperresponsiveness differently [PDF]

, 2012
BACKGROUND: Epidemiological data indicate that obesity is a risk factor for asthma, but scientific literature is still debating the association between changes in body mass index (BMI) and airway hyperresponsiveness (AHR).
Balducci, M, Migliorini, M, Pammolli, A, Scala, R., Scalese, M, SCICHILONE, Nicola Alessandro, Sposato, B   +6 more
core   +2 more sources

Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma

Frontiers in Immunology, 2019
Inflammation, reversible obstruction, and hyperresponsiveness of the airways are characteristic findings of bronchial asthma. Several evidence has demonstrated the involvement of matrix metalloproteinase-2 in allergic airway inflammation.
Yoshinori Takahashi, Tetsu Kobayashi, Corina N. D'Alessandro-Gabazza, Masaaki Toda, Kentaro Fujiwara, Tomohito Okano, Hajime Fujimoto, Kentaro Asayama, Atsuro Takeshita, Atsuro Takeshita, Taro Yasuma, Taro Yasuma, Kota Nishihama, Ryo Inoue, Liqiang Qin, Yoshiyuki Takei, Osamu Taguchi, Esteban C. Gabazza   +17 more
doaj   +1 more source

A half doubling dose change in bronchial hyperresponsiveness in a population represents an important difference [PDF]

, 2013
Background The prevalence of asthma has increased over recent decades and the reasons for this are poorly understood. A sensitive tool that can evaluate potential risk factors for asthma is bronchial hyperresponsiveness (BHR), a key ...
James Fingleton, Mark Weatherall, Richard Beasley, Sally Eyers   +3 more
core   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

Remodelling and Inflammation in Bronchial Asthma

European Journal of Inflammation, 2003
Chronic stable asthma is characterized by inflammation of the airway wall, with abnormal accumulation of basophils, eosinophils, lymphocytes, mast cells, macrophages, dendritic cells and myofibroblasts.
G. Riccioni, N. D'Orazio, R. Della Vecchia, T. Iezzi, C. Di Ilio   +4 more
doaj   +1 more source

Respiratory function and bronchial responsiveness among industrial workers exposed to different classes of occupational agents: a study from Algeria

Journal of Occupational Medicine and Toxicology, 2007
Occupational exposures play a role in the onset of several chronic airway diseases. We investigated, in a cross-sectional study, lung function parameters and bronchial hyper-responsiveness to histamine in workers exposed to different airborne compounds ...
Hoet Peter H, Nawrot Tim S, Ould-Kadi Farid, Nemery Benoit   +3 more
doaj   +1 more source

気管支喘息に対する複合温泉療法の作用機序 1.温泉療法の評価方法との関連 [PDF]

, 1996
Action mechanisms of complex spa therapy (swimming training in a hot spring pool, inhalation with iodine salt solution, and fango therapy) were studied in relation to patient age, clinical asthma type, and airway inflammation. Actions of spa therapy were
Ashida, Kozo, Harada, Hideo, Hosaki, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Nawa, Yuichiro, Ochi, Koji, Takeuchi, Kazuaki, Tanizaki, Yoshiro, Tsugeno, Hirofumi, Yokota, Satoshi   +10 more
core   +1 more source

Effects of photobiomodulation therapy on pulmonary inflammation in chronic asthma: Dosimetric study in an experimental model

Photochemistry and Photobiology, EarlyView.
Photobiomodulation therapy (PBMT) was evaluated across a radiant energy range (1–7.5 J) in a murine model of chronic ovalbumin‐induced asthma to identify the optimal therapeutic dose. PBMT attenuated airway inflammation and remodelling, suppressed Th2 cytokines, and enhanced regulatory immune responses, highlighting a dose‐dependent immunomodulatory ...
Tawany Gonçalves Santos, Cintia Estefano Alves, Bibiana Padilha de Menezes da Silva, Cinthya Cosme Gutierrez Duran, Stella Zamuner, Rodrigo Labat, José Antonio Silva Junior, Maria Cristina Chavantes, Flavio Aimbire, Renata Kelly da Palma, Ana Paula Ligeiro de Oliveira   +10 more
wiley   +1 more source

Is platelet activating factor (PAF) an important mediator in bronchial asthma?

Mediators of Inflammation, 1992
The development of selective PAF receptor antagonists may provide a novel approach to the treatment of human bronchial asthma. In preclinical animal models of human asthma, PAF receptor antagonists have been found to be efficacious in blocking antigen ...
R. H. Gundel, H. O. Heuer, L. G. Letts
doaj   +1 more source

Environmental tobacco smoke, indoor allergens, and childhood asthma. [PDF]

, 2011
Both environmental tobacco smoke and indoor allergens can exacerbate already established childhood albeit primarily through quite disparate mechanisms.
Gold, Diane R.
core   +1 more source