Results 31 to 40 of about 88,868 (211)

Changes in functional status and inflammation profile in patients with chronic obstructive pulmonary disease during therapy with tiotropium

Медицинский совет, 2015
The article tells about the results of evaluating the effects of tiotropium on the level of bronchial hyperresponsiveness (BHR) and comparing its clinical efficacy in patients with chronic obstructive pulmonary disease (COPD) depending on the level of ...
I. N. Trofimenko, B. A. Chernyak
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Relationship between Exhaled Nitric Oxide Measured by Two Offline Methods and Bronchial Hyperresponsiveness in Japanese Adults with Asthma

Allergology International, 2008
Background: Exhaled nitric oxide (eNO) is a useful marker of eosinophilic airway inflammation in asthmatics. There have been no studies to show the relationship between eNO measured by offline methods and the degree of bronchial hyperresponsiveness in ...
Takahiro Tsuburai, Naomi Tsurikisawa, Sonoko Morita, Hideki Hasunuma, Hiroshi Kanegae, Yasushi Ishimaru, Yuma Fukutomi, Hidenori Tanimoto, Emiko Ono, Chiyako Oshikata, Kiyoshi Sekiya, Mamoru Otomo, Yuji Maeda, Masami Taniguchi, Kunihiko Ikehara, Kazuo Akiyama   +15 more
doaj   +1 more source

Asthma: Cells involved in the pathophysiology of asthma

The Journal of Association of Chest Physicians, 2023
Asthma is a complex chronic inflammatory disease of the bronchioles characterized by airway hyperresponsiveness, bronchial hyperresponsiveness, and airway obstruction. Asthma is classified into various types.
Vivek Shinde, Pavankumar Wankhede, Neeraj Vyawahare   +2 more
doaj   +1 more source

Determinants of Bronchial Hyperresponsiveness in Subjects with Rhinitis [PDF]

International Journal of Immunopathology and Pharmacology, 2005
Subjects with rhinitis but without asthma may have coexisting bronchial hyperresponsiveness, although the reasons for this are uncertain. To evaluate the factors that determine BHR in rhinitis we examined 410 patients with symptomatic rhinitis with forced expiratory volume in 1 second (FEV 1 )
DI LORENZO, Gabriele, PACOR ML, MANSUETO, Pasquale, ESPOSITO PELLITTERI, Maria, LO BIANCO, Claudia, DITTA, Vito, LETO BARONE MS, NAPOLI N, DI FEDE, Gaetana, RINI, Giovam Battista   +9 more
openaire   +4 more sources

Trends in the Asthma Burden Attributable to High Body Mass Index in Children Across 204 Countries and Territories, 1990–2021: An Analysis of the 2021 Global Burden of Disease Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT High body mass index (BMI) has been identified as a significant risk factor for childhood asthma. Given the rising prevalence of childhood obesity, assessing the impact of high BMI on asthma burden trends is imperative. Utilizing Global Burden of Disease (GBD) data, we estimated age‐, sex‐, geography‐, and sociodemographic index (SDI ...
Hua Li, Hai‐Yan Chen, Dong‐Zhi Zheng, Qiu‐Yi Liu, Jia‐Bing Li   +4 more
wiley   +1 more source

A Guinea Pig Model of Airway Smooth Muscle Hyperreactivity Induced by Chronic Allergic Lung Inflammation: Contribution of Epithelium and Oxidative Stress

Frontiers in Pharmacology, 2019
Asthma is a heterogeneous disease of the airways characterized by chronic inflammation associated with bronchial and smooth muscle hyperresponsiveness. Currently, different murine models for the study of asthma show poor bronchial hyperresponsiveness due
Luiz Henrique César Vasconcelos, Maria da Conceição Correia Silva, Alana Cristina Costa, Giuliana Amanda de Oliveira, Iara Leão Luna de Souza, Fernando Ramos Queiroga, Layanne Cabral da Cunha Araujo, Glêbia Alexa Cardoso, Renato Fraga Righetti, Renato Fraga Righetti, Alexandre Sérgio Silva, Alexandre Sérgio Silva, Patrícia Mirella da Silva, Patrícia Mirella da Silva, Carla Roberta de Oliveira Carvalho, Carla Roberta de Oliveira Carvalho, Giciane Carvalho Vieira, Iolanda de Fátima Lopes Calvo Tibério, Fabiana de Andrade Cavalcante, Fabiana de Andrade Cavalcante, Bagnólia Araújo da Silva, Bagnólia Araújo da Silva   +21 more
doaj   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

Pediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You, Wenjing Zou, Tangqiaochu Gan, Yu Zhao, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Zhengxiu Luo, Zhou Fu, Chao Niu   +10 more
wiley   +1 more source

Updating the concept of asthma. Is asthma a syndrome?

Revista Alergia México, 2015
Several symptoms are common to different processes that affect the respiratory system and their precise assessment is key to a correct diagnosis. Amongst those symptoms, mostly dyspnoea oriented toward the possible diagnosis of asthma.
Francisco Muñoz-López
doaj   +1 more source