Results 11 to 20 of about 28,269 (237)

The usefulness of bronchial challenge tests in the diagnosis of occupational asthma

Medycyna Pracy, 2018
Bronchial hyperresponsiveness (BHR) is the individual ability to respond with bronchoconstriction to a variety of specific and nonspecific stimuli which do not cause these symptoms among healthy subjects.
Ewa Nowakowska-Świrta, Marta Wiszniewska, Jolanta Walusiak-Skorupa   +2 more
doaj   +1 more source

Challenging case of severe acute asthma in a mechanically ventilated patient managed with sevoflurane

Clinical Case Reports, 2023
Acute severe bronchial asthma is a chronic inflammatory disease characterized by hyperresponsiveness of the airways leading to bronchoconstriction. We present a case of refractory life‐threatening bronchial asthma that was managed with sevoflurane gas ...
Satheesh Munusamy, Seyedeh Saba Nabavi Monfared, Phool Iqbal, Ahmed Lutfe Mohamad Abdussalam   +3 more
doaj   +1 more source

Bronchial thermoplasty : a new therapeutic option for the treatment of severe, uncontrolled asthma in adults [PDF]

, 2014
Bronchial thermoplasty is a young yet promising treatment for severe asthma whose benefit for long-term asthma control outweighs the short-term risk of deterioration and hospitalisation in the days following the treatment.
Alagha, Khuder, Aubier, Michel, Boulet, Louis Philippe, Brillet, Pierre Yves, Chanez, Pascal, Dombret, Marie-Christine, Joos, Guy, Laviolette, Michel, Louis, Renaud, Rochat, Thierry, Soccal, Paola   +10 more
core   +5 more sources

Glucocorticoids Ameliorate Antigen-Induced Bronchial Smooth Muscle Hyperresponsiveness by Inhibiting Upregulation of RhoA in Rats

Journal of Pharmacological Sciences, 2008
To determine the mechanism(s) of the inhibitory effect of glucocorticoids on airway hyperresponsiveness in allergic bronchial asthma, the effects of systemic treatment with glucocorticoids on bronchial smooth muscle hyperresponsiveness and RhoA ...
Yoshihiko Chiba, Kumiko Goto, Mayu Hirahara, Hiroyasu Sakai, Miwa Misawa   +4 more
doaj   +1 more source

Special Issue on ‘Asthma and Allergic Inflammation’

Vaccines, 2023
Asthma is a chronic inflammatory airway disease, driven by either allergic or non-allergic stimuli, which usually manifests as wheezing, reversible airflow limitation, and bronchial hyperresponsiveness [...]
Corrado Pelaia
doaj   +1 more source

Role of Rac1 in augmented endothelin-1-induced bronchial contraction in airway hyperresponsive mice

Journal of Pharmacological Sciences, 2019
It has recently been exhibited that Rac1 expression is increased in the bronchial tissue of a murine model with repeated antigen-challenged airway hyperresponsiveness (AHR).
Yuki Kai, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Junzo Kamei, Hiroyasu Sakai   +5 more
doaj   +1 more source

SKI-II, an Inhibitor of Sphingosine Kinase, Ameliorates Antigen-Induced Bronchial Smooth Muscle Hyperresponsiveness, but Not Airway Inflammation, in Mice

Journal of Pharmacological Sciences, 2010
.: To determine if endogenously generated sphingosine-1-phosphate (S1P) is involved in the development of allergic bronchial asthma, the effects of systemic treatments with SKI-II, a specific inhibitor of sphingosine kinase, on antigen-induced bronchial ...
Yoshihiko Chiba, Hiroki Takeuchi, Hiroyasu Sakai, Miwa Misawa   +3 more
doaj   +1 more source

Bronchial and nasal responsiveness in atopic asthma and allergic rhinitis patients: Relationship of local responsiveness to cytokine production by peripheral blood mononuclear cells

Allergology International, 1998
To investigate the relationship between local responsiveness and allergic symptoms, bronchial and nasal responsiveness were measured in the following four groups of subjects: (i) bronchial asthma patients with serum house dust mite (HDM)-specific IgE ...
Keiji Maeda, Toshio Tanaka, Yoshinobu Katada, Arata Horii, Kimihiro Nose, Hiroshi Ochi, Satoshi Ogino, Masaki Suemura, Tadamitsu Kishimoto, Tsuyoshi Igarashi   +9 more
doaj   +1 more source

Mechanisms altering airway smooth muscle cell Ca(2+) homeostasis in two asthma models [PDF]

, 2008
Background: Asthma is characterized by airway remodeling, altered mucus production and airway smooth muscle cell (ASMC) contraction causing extensive airway narrowing. In particular, alterations of ASMC contractility seem to be of crucial importance. The
Bergner, Albrecht, Edelmann, Martin, Fischer, Rainald, Huber, Rudolf M., Kellner, Julia, Oelmez, Hamza, Tantzscher, Juliane   +6 more
core   +1 more source

The multifaceted role of placental growth factor in the pathogenesis and progression of bronchial asthma and pulmonary fibrosis: Therapeutic implications

Genes and Diseases, 2023
Placental growth factor (PlGF) is a glycosylated dimeric protein that is homologous to vascular endothelial growth factor (VEGF). PlGF expression is upregulated in patients with bronchial asthma, suggesting that it plays a role in the pathogenesis of ...
Dan Huang, Gege Liu, Zhiyi Xu, Shushu Chen, Cuili Wang, Dewei Liu, Jiahao Cao, Junfen Cheng, Bin Wu, Dong Wu   +9 more
doaj   +1 more source