Seasons can influence the results of the methacholine challenge test
Annals of Thoracic Medicine, 2012 Objective: This study tried to evaluate whether a methacholine test may be influenced by the seasons. Methods: We considered 4826 consecutive subjects with normal spirometry (50.53% males; age: 35.1±16.2; forced expiratory volume in one second: 99.5±13 ...
Bruno Sposato +4 more
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New insights into the regulation of TGF‐β/Smad and MPK signaling pathway gene expressions by nasal allergen and methacholine challenge test in asthma [PDF]
Clinical and Translational Allergy, 2022 Background Asthma is a heterogeneous chronic inflammatory disease of the bronchi, the course of which is significantly influenced by extrinsic factors (specific and non‐specific).
Michał Gabriel Panek +6 more
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Presence of variable extrathoracic airflow limitation in patients with a negative methacholine challenge test [PDF]
Allergy, Asthma & Clinical Immunology, 2023 Purpose Determine whether variable extrathoracic airflow limitation (VEAL) is observed in patients with negative methacholine challenge tests (MCT). Methods Electronic medical records of patients undergoing MCT at Jesse Brown VA Medical Center between ...
Zane Z. Elfessi +2 more
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Bronchodilator Response in Patients with Persistent Allergic Asthma Could Not Predict Airway Hyperresponsiveness [PDF]
Allergy, Asthma & Clinical Immunology, 2007 Anticholinergics, or specific antimuscarinic agents, by inhibition of muscarinic receptors cause bronchodilatation, which might correlate with activation of these receptors by the muscarinic agonist methacholine.
Petanjek Bojana B +3 more
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Correlation between Reduced FEF25-75% and a Positive Methacholine Challenge Test in Adults with Nonobstructive Baseline Spirometry [PDF]
Pulmonary Medicine, 2021 Rationale. FEF25-75% is routinely reported on spirometry and is thought to be a marker of small airway obstruction. It is reduced in children with asthma, but its significance in adults and especially those without asthma diagnosis remains unclear ...
Irfan Shafiq +5 more
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Methacholine challenge testing: comparative pharmacology
Journal of Asthma and Allergy, 2018 Beth E Davis, Christianne M Blais, Donald W Cockcroft Division of Respirology, Critical Care and Sleep Medicine, Department of Medicine, University of Saskatchewan, Saskatoon, SK, Canada Abstract: Standardization of the methacholine inhalation challenge,
Davis BE, Blais CM, Cockcroft DW
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Comparing the inhalation of methacholine chloride and methacholine for methacholine challenge testing [PDF]
European Journal of Medical ResearchBackground Bronchial challenge testing with methacholine was applied to evaluate and quantify bronchial hyperresponsiveness (BHR) in asthma patients.
Meiping Chen +4 more
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The value of small airway function parameters and fractional exhaled nitric oxide for predicting positive methacholine challenge test in asthmatics of different ages with FEV1 ≥ 80% predicted [PDF]
Clinical and Translational Allergy, 2021 Background Small airway function parameters (SAFPs) combined with fractional exhaled nitric oxide (FeNO) can predict a positive methacholine challenge test (MCT) for asthma diagnosis.
Lili Hou +7 more
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Relation of Changes in PEF and FEV1 During Salbutamol-Induced Bronchodilation After Methacholine Challenge Test [PDF]
Pulmonary MedicineAsthma diagnosis can be confirmed by observing significant bronchodilator response (BDR) through peak expiratory flow (PEF) at home or forced expiratory volume in 1 s (FEV1) via spirometry in a clinical setting.
Leon L. Csonka +4 more
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Annals of Cardiac Anaesthesia, 2015 Introduction: Exertional-induced bronchoconstriction is a condition in which the physical activity causes constriction of airways in patients with airway hyper- responsiveness.
Mostafa Ghanei +3 more
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