Time-dependent effect of prostaglandin E2 inhalation on airway responses to bronchoconstrictor agents in normal subjects. [PDF]
Thorax, 1982 Studies were performed to investigate whether hyperresponsiveness of the airways could be induced in normal subjects by inhalation of prostaglandin E2 (PGE2). During the initial bronchodilator phase of PGE2 action the bronchoconstrictor effect of inhaled histamine was significantly antagonised.
E H, Walters +4 more
openaire +3 more sources
BMC Pulmonary Medicine, 2021 Background Methacholine challenge tests (MCTs) are used to diagnose airway hyperresponsiveness (AHR) in patients with suspected asthma where previous diagnostic testing has been inconclusive.
Michael Peled +6 more
doaj +1 more source
Effect of β‐adrenoceptive blocking agents on the response to bronchoconstrictor drugs in the guinea‐pig air overflow preparation [PDF]
British Journal of Pharmacology, 1971 Summary Propranolol augmented the bronchoconstrictor response to methacholine or histamine, recorded by air overflow in the anaesthetized, vagotomized guinea‐pig. After adrenalectomy, propranolol was still active, though less so than before. In the pithed guinea‐pig, there was no augmentation of the effect of bronchoconstrictors on air overflow.
D T, Burden, M W, Parkes, D G, Gardiner
openaire +2 more sources
Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse [PDF]
, 2006 Background It has been proposed that serotonin (5-HT)-mediated constriction of the murine trachea is largely dependent on acetylcholine (ACh) released from the epithelium.
Akinci, Sibel +8 more
core +3 more sources
Bronchodilator Response in Patients with Persistent Allergic Asthma Could Not Predict Airway Hyperresponsiveness [PDF]
, 2007 Anticholinergics, or specific antimuscarinic agents, by inhibition of muscarinic receptors cause bronchodilatation, which might correlate with activation of these receptors by the muscarinic agonist methacholine.
Petanjek Bojana B +3 more
core +2 more sources
Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events [PDF]
, 2012 An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in previous Cochrane reviews.ObjectivesWe set out to compare the risks of mortality and non-fatal serious adverse events in ...
Altman +18 more
core +1 more source
Allergy, Asthma & Clinical Immunology, 2010 Background Little information is available on the effect of allergen-specific immunotherapy on airway responsiveness and markers in exhaled air. The aims of this study were to assess the safety of immunotherapy with purified natural Alt a1 and its effect
Prieto Luis +6 more
doaj +1 more source
Adenosine signaling in airways: Toward a promising antiasthmatic approach [PDF]
, 2013 Adenosine participates to asthma physiopathology by signaling through more than just one receptor subtype. Defining the role of each receptor is complicated by evidence that often results obtained on rodents do not coincide with human studies, but what ...
CICALA, CARLA, IALENTI, ARMANDO
core +1 more source
Iranian journal of pharmaceutical research : IJPR, 2012 Cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. However, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.
Mombeini, Tajmah +2 more
openaire +2 more sources
Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]
, 2014 The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard +4 more
core +4 more sources