Results 31 to 40 of about 26,256 (214)

The effect of glycopyrronium and indacaterol, as monotherapy and in combination, on the methacholine dose-response curve of mild asthmatics: a randomized three-way crossover study

Respiratory Research, 2017
Background Methacholine dose-response curves illustrate pharmacologic bronchoprotection against methacholine-induced airway hyperresponsiveness and can be used to quantitate changes in airway sensitivity (position), reactivity (slope), and maximal ...
Christianne M. Blais, Beth E. Davis, Donald W. Cockcroft   +2 more
doaj   +1 more source

Methacholine challenges: comparison of different tidal breathing challenge methods

ERJ Open Research, 2021
Tidal-breathing methacholine challenges are now recommended by guidelines, to avoid the bronchoprotective effects of deep inhalation. This study compared different tidal breathing methacholine challenge methods; assessed the agreement between tidal ...
James Dean, Natalie Jackson, Brett Keidel-Morgan, Daniel Hamer, Dave Singh   +4 more
doaj   +1 more source

Methacholine induced headache. [PDF]

Thorax, 1995
A lung function technician developed episodes of headache, probably related to the use of methacholine. The headache disappeared with breathing 100% oxygen. Cholinergic agents are known to induce headaches but the mechanism remains unclear. Vascular factors could be implicated.
C, Carratala, J G, Gea, M C, Aguar, S, Grau, J M, Espadaler-Medina, J M, Broquetas   +5 more
openaire   +2 more sources

Low-Dose Oral Ginger Improves Daily Symptom Scores in Asthma

Pharmaceuticals
Background/Objective: A significant number of individuals with asthma have poorly controlled daily symptoms and utilize dietary supplements such as ginger in a quest for improved symptom control; however, its effectiveness at improving the control of ...
Charles W. Emala, Tarnjot K. Saroya, Yuqi Miao, Shuang Wang, Shengmin Sang, Emily A. DiMango   +5 more
doaj   +1 more source

Effect of constant light and immobilization stress on rat submandibular saliva secretory response induced by cholinergic and peptidergic agonists

Journal of Oral Research, 2018
The aim of this work was to analyse the parasympathetic control of submandibular saliva secretory response to cholinergic and peptidergic agonists in rats chronically exposed to constant light or repeated immobilization. Thirty two adult male Wistar rats
Raquel Gallará, Rubén Ponce, Viviana Centeno, Salvador Bellavía   +3 more
doaj   +1 more source

Approach to the diagnosis and management of suspected exercise-induced bronchoconstriction by primary care physicians [PDF]

, 2009
Background Exercise-related respiratory symptoms in the diagnosis of exercise-induced bronchoconstriction (EIB) have poor predictive value. The aim of this study was to evaluate how athletes presenting with these symptoms are diagnosed and managed in ...
James H Hull, Peter J Hull, Jonathan P Parsons, John W Dickinson, Les Ansley, JW Dickinson, JP Parsons, JH Hull, SD Anderson, K Holzer, KW Rundell, SD Anderson, JP Parsons, LB Schwartz, H Johansson, KH Carlsen, KD Fitch, K Holzer, I Helenius, SD Anderson, M Sue-Chu, TD Mickleborough, TD Mickleborough, TD Mickleborough, M Cullen, P Greenway, P Laure   +26 more
core   +2 more sources

Staphylococcal enterotoxin sensitization in a community-based population : a potential role in adult-onset asthma [PDF]

, 2014
Background: Recent studies suggest that Staphylococcus aureus enterotoxin sensitization is a risk factor for asthma. However, there is a paucity of epidemiologic evidence on adult-onset asthma in community-based populations.
Bachert, Claus, Chang, Yoon-Seok, Cho, Sang-Heon, Choi, Min-Ho, Kang, Hye-Ryun, Kim, Sae-Hoon, Lim, Min Kyung, Min, Kyung-Up, Park, Heung-Woo, Song, Woo-Jung, Tomassen, Peter, Yun, E Hwa   +11 more
core   +2 more sources

Family and twin studies on methacholine hypersensitivity

Allergology International, 1998
Essentially all asthmatics demonstrate a marked sensitivity to inhaled methacholine and histamine, termed non-specific bronchial (airway) hyperresponsiveness (BHR).
Robert G Townley
doaj   +1 more source

Use of a vibrating mesh nebulizer for allergen challenge

Allergy, Asthma & Clinical Immunology, 2019
Background Allergen inhalation tests are a valuable research tool. The allergen dose producing an early asthmatic response (EAR) can be predicted from methacholine responsiveness and allergen skin test endpoint (STE).
Donald W. Cockcroft, Beth E. Davis, Christianne M. Blais, Louis-Philippe Boulet, Marie-Éve Boulay, Hélène Villeneuve, Gail M. Gauvreau, Paul M. O’Byrne, Karen J. Howie, Caitlin D. Obminski   +9 more
doaj   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source