Results 51 to 60 of about 26,256 (214)

Regular treatment with formoterol for chronic asthma: serious adverse events [PDF]

open access: yes, 2012
Epidemiological evidence has suggested a link between beta(2)-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are safe ...
Altman   +17 more
core   +1 more source

Airway response to methacholine following eucapnic voluntary hyperpnea in athletes. [PDF]

open access: yesPLoS ONE, 2015
To evaluate the changes in airway responsiveness to methacholine inhalation test (MIT) when performed after an eucapnic voluntary hyperpnea challenge (EVH) in athletes.Two MIT preceded (visit 1) or not (visit 2) by an EVH, were performed in 28 athletes ...
Valérie Bougault   +3 more
doaj   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi   +10 more
wiley   +1 more source

Exercise-induced bronchoconstriction in children with asthma: An observational cohort study

open access: yesJournal of Microbiology, Immunology and Infection, 2019
Background/purpose: The diagnosis of exercise-induced bronchoconstriction (EIB) was established by changes in lung function after exercise challenge. The prevalence of EIB and factors related to EIB were not fully described in children with asthma.
Li-Lun Lin   +6 more
doaj   +1 more source

Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events [PDF]

open access: yes, 2012
An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in previous Cochrane reviews.ObjectivesWe set out to compare the risks of mortality and non-fatal serious adverse events in ...
Altman   +18 more
core   +1 more source

The testosterone paradox in asthma

open access: yesFrontiers in Allergy
Asthma and an excessive response to inhaled methacholine, commonly called hyperresponsiveness, are intimately linked. Therefore, factors increasing the methacholine response are expected to contribute to asthma as well.
Ynuk Bossé
doaj   +1 more source

Prevalence of airway hyperresponsiveness and its seasonal variation in children with asthma

open access: yesPediatrics and Neonatology, 2018
Background: Airway hyperresponsiveness (AHR) is a key feature of asthma and can be detected using various bronchoprovocation tests. In pediatric populations, the percentage of a positive methacholine challenge test (MCCTs) in children with asthma varies ...
Shu-Jung Huang   +7 more
doaj   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

open access: yesCell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang   +10 more
wiley   +1 more source

Standardization of methacholine inhalation challenge

open access: yesThe Turkish Journal of Pediatrics, 1997
Methacholine inhalation challenge has been shown to be an extremely useful diagnostic test. The purpose of this study was to document the reproducibility of methacholine inhalation challenge used in our clinic.
B E Sekerel   +4 more
doaj  

Exertional-induced bronchoconstriction: Comparison between cardiopulmonary exercise test and methacholine challenging test

open access: yesAnnals of Cardiac Anaesthesia, 2015
Introduction: Exertional-induced bronchoconstriction is a condition in which the physical activity causes constriction of airways in patients with airway hyper- responsiveness.
Mostafa Ghanei   +3 more
doaj   +1 more source

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