Results 71 to 80 of about 26,256 (214)
Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices. [PDF]
PLoS ONE, 2013 Airway remodelling, including smooth muscle remodelling, is a primary cause of airflow limitation in asthma. Recent evidence links bronchoconstriction to airway remodelling in asthma. The mechanisms involved are poorly understood.
Tjitske A Oenema +5 more
doaj +1 more source
Airway resistance at maximum inhalation as a marker of asthma and airway hyperresponsiveness [PDF]
, 2011 Background Asthmatics exhibit reduced airway dilation at maximal inspiration, likely due to structural differences in airway walls and/or functional differences in airway smooth muscle, factors that may also increase airway responsiveness to ...
Nancy T Mendonça +5 more
core +2 more sources
Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.ABSTRACT Background Asthma is characterized by chronic airway inflammation and remodeling. Polydatin (PD), a natural compound, has shown anti‐inflammatory potential, but its role in asthma‐related airway remodeling and the underlying mechanisms involving the P2X7R–NLRP3 inflammasome axis and autophagy remain unclear.
Guangxing Li +8 more
wiley +1 more source
Evaluation of Methacholine Challenge Test Results in Chronic Cough Patients Referring to Clinic of Pulmonary Disease [PDF]
Acta Medica Iranica, 2009 Chronic cough is a common problem in patients visiting physicians and its prevalence in different populations range from 3 to 40%. Postnasal drip, asthma and gastroesophageal reflux are the known cause of chronic cough.
Derakhshan Deilami Gholamreza +3 more
doaj +2 more sources
Clinical and Translational Allergy, 2022 Background Asthma is a heterogeneous chronic inflammatory disease of the bronchi, the course of which is significantly influenced by extrinsic factors (specific and non‐specific).
Michał Gabriel Panek +6 more
doaj +1 more source
Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice. [PDF]
, 2019 Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease.
Flayer, Cameron H +6 more
core
The role of L-carnitine in treatment of a murine model of asthma. [PDF]
, 2002 Leukotrienes, one of the mediators of inflammation in asthma, have a strong bronchoconstrictive effect. L-carnitine has been reported to influence respiratory functions. It has also been reported that L-carnitine inhibits leukotriene synthesis.
Islekel, Huray +7 more
core +2 more sources
Nematode in Cockroaches: A Potential Allergen Source
Allergy, EarlyView.
Dongjun Kang +5 more
wiley +1 more source
Protective Role for Itaconate During Inhaled Allergen Challenge
Allergy, Volume 81, Issue 4, Page 1099-1110, April 2026.Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers +16 more
wiley +1 more source
The Effects of Long-Term Administration of Sodium Nedocromil on Bronchial Hypereactivity
European Journal of Inflammation, 2003 The effect of long-term treatment with sodium nedocromil on airway hypereactivity was investigated in two groups of 20 patients each. Group I patients presented with allergic asthma while Group II patients presented with intrinsic asthma.
G. Ilonidis +8 more
doaj +1 more source