Results 61 to 70 of about 26,256 (214)

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, Volume 183, Issue 9, Page 2049-2060, May 2026.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source

Methacholine and PDGF activate store-operated calcium entry in neuronal precursor cells via distinct calcium entry channels

Biological Research, 2008
Neurons are a diverse cell type exhibiting hugely different morphologies and neurotransmitter specifications. Their distinctive phenotypes are established during differentiation from pluripotent precursor cells.
PAUL CUDDON, MARTIN D BOOTMAN, GILLIAN R RICHARDS, ALISON J SMITH, PETER B SIMPSON, H LLEWELYN RODERICK   +5 more
doaj  

Benzydamine Oral Spray Inhibiting Parasympathetic Function of Tracheal Smooth Muscle [PDF]

Clinical and Experimental Otorhinolaryngology, 2015
ObjectivesBenzydamine is a nonsteroidal anti-inflammatory agents agent with anti-inflammatory and local anesthesia properties that is available in the entire world as an oral spray for oral mucositis patients who are suffering from radiation effects. The
Hsing-Won Wang, Pin-Zhir Chao, Fei-Peng Lee, Jia-Yi Wang   +3 more
doaj   +1 more source

Integrating evidence for managing asthma in patients who smoke [PDF]

, 2014
Peer reviewedPublisher ...
Bjermer, Leif, Chisholm, Alison, Popov, Todor A, Price, David   +3 more
core   +1 more source

The Global Airways in Practice: Long‐term Effects of Mepolizumab With or Without FESS on Type 2 Inflammation in Patients With CRSwNP

International Forum of Allergy &Rhinology, Volume 16, Issue 4, Page 369-379, April 2026.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often associated with asthma. The global airway hypothesis suggests bidirectional inflammatory interactions between upper and lower airways. Mepolizumab, an anti–IL‐5 therapy, treats conditions systemically, while functional endoscopic sinus surgery ...
Jens Tidemandsen, Vibeke Backer, Anne Sophie Homøe, Thomas H. L. Jensen, Kasper Aanæs, Howraman Meteran, Morten Hostrup, Lukas Moesgaard, Christiane Haase, Peter G. Gibson   +9 more
wiley   +1 more source

Impaired vascular relaxation in type 2 diabetes

EXCLI Journal : Experimental and Clinical Sciences
Type 2 diabetes (T2D) significantly increases the risk of vascular complications (12-32 %), which are a major cause of death (over 50 %) in T2D patients.
Sajad Jeddi, Zahra Bahadoran, Parvin Mirmiran, Khosrow Kashfi, Asghar Ghasemi   +4 more
doaj   +1 more source

The Diagnosis of Asthma

Canadian Respiratory Journal, 2004
In this issue of the Canadian Respiratory Journal, LindenSmith et al (pages 111 to 116) present data that strongly suggest that patients who do not have asthma frequently acquire this diagnosis.
Nick R Anthonisen
doaj   +1 more source

Associations Between Different Eosinophil Activity Markers and Clinical Outcomes in Young Asthmatics

Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.
ABSTRACT Background Identifying biomarkers for different aspects of asthma morbidity is crucial for effective disease monitoring and management. The performance of fractional exhaled nitric oxide (FeNO), blood eosinophil count (BEC), and eosinophil activity markers should be evaluated. Objective This study aimed to compare the associations of FeNO, BEC,
Nils Oskar Jõgi, Nikolaos Tsolakis, Anders Sjölander, Robert Movérare, Christer Janson, Andrei Malinovschi, Kjell Alving   +6 more
wiley   +1 more source

More Relaxation by Deep Breath on Methacholine- Than on Exercise-Induced bronchoconstriction during the Routine Testing of Asthmatic Children

Frontiers in Physiology, 2017
Deep inspiration (DI) dilates normal airway precontracted with methacholine. The fact that this effect is diminished or absent in asthma could be explained by the presence of bronchial inflammation.
Iulia Ioan, Iulia Ioan, Aurélie Tatopoulos, Stéphanie Metche, Laurianne Coutier, Emmanuelle Houriez, Sébastien Kiefer, Aurore Blondé, Claude Bonabel, Claude Bonabel, François Marchal, François Marchal, Jocelyne Derelle, Cyril E. Schweitzer, Cyril E. Schweitzer, Cyril E. Schweitzer, Silvia Demoulin-Alexikova, Silvia Demoulin-Alexikova   +17 more
doaj   +1 more source