Results 51 to 60 of about 79,822 (211)

Pathological Roles of Neutrophil-Mediated Inflammation in Asthma and Its Potential for Therapy as a Target

Journal of Immunology Research, 2017
Asthma is a chronic inflammatory disease that undermines the airways. It is caused by dysfunction of various types of cells, as well as cellular components, and is characterized by recruitment of inflammatory cells, bronchial hyperreactivity, mucus ...
Han Gao, Songmin Ying, Yuanrong Dai
doaj   +1 more source

Characteristics of epidemiological and molecular relationships between allergic diseases and helminth disorders in Opisthorchis endemic region

Бюллетень сибирской медицины, 2008
To elucidate the molecular mechanisms of O. felineus impact into phenotypic variability of allergic diseases in the opisthorchis endemic region, we studied 104 patients with opisthorchosis, 92 patients with atopic bronchial asthma, 52 patients with a ...
L. M. Ogorodova, O. S. Fyodorova, M. B. Freidin, M. B. Vasil’yeva, N. A. Cherevko, A. E. Sazonov, I. V. Petrova, I. V. Saltykova, Ye. Yu. Bragina, Ye. S. Kulikov, I. A. Deyev   +10 more
doaj   +1 more source

Effect of baclofen on different models of bronchial hyperreactivity in the guinea-pig

, 1987
In this paper we report an inhibitory effect of (-)-baclofen on many models of bronchial hyperreactivity both in vivo and in vitro. (-)-Baclofen protects guinea-pigs from the anaphylactic bronchospasm induced in sensitized animals by an ovalbumin aerosol
G. Rossoni, S. Luzzi, L. Zilletti, M. Ciuffi, S. Franchi Micheli, G. Folco   +5 more
core   +1 more source

Section 2. Exercise-Induced Bronchospasm: Albuterol versus Montelukast

World Allergy Organization Journal, 2010
Exercise-induced bronchospasm (EIB) involves airway obstruction with an onset shortly after exercising. It can occur in individuals without a diagnosis of asthma, but is most common in asthmatic patients (and in this scenario may be referred to as ...
Gene Colice, MD, FCCP, William J. Calhoun, MD, FACP, FCCP, FAAAAI, FACAAI   +1 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Mast cells are essential in the development of exposure-associated exercise-induced bronchoconstriction in a mouse model

Frontiers in Immunology
BackgroundCold air and air pollution are known triggers to induce symptoms in exercise-induced bronchoconstriction (EIB). Mast cells are hypothesized to be a key player in the pathogenesis of EIB.
Nora F. Marain, Fien Byttebier, Marieke Colemont, Ellen Dilissen, Jonathan Cremer, Dominique MA Bullens, Dominique MA Bullens, Lieven J. Dupont, Lieven J. Dupont, Jeroen A. Vanoirbeek   +9 more
doaj   +1 more source

Bronchial hyperreactivity and spirometric impairment in patients with allergic rhinitis

Monaldi Archives for Chest Disease, 2005
Background: The Link between allergic rhinitis and asthma is well known. Bronchial hyperreactivity (BHR) may be present in rhinitics. The present study is aimed at evaluating a large group of subjects suffering from allergic rhinitis alone to investigate
I. Cirillo, A. Vizzaccaro, M.A. Tosca, S. Negrini, A.C. Negrini, G. Marseglia, G. Ciprandi   +6 more
doaj   +1 more source

MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation

Allergy, Volume 81, Issue 9, Page 3236-3249, September 2026.
In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata, Jaclyn W. McAlees, Julie M. Hargis, Archana Shankar, Shouxiong Huang, Senad Divanovic, Ian P. Lewkowich   +6 more
wiley   +1 more source

Bronchial hyperreactivity in patients with endobronchial tuberculosis

, 1995
Some patients with endobronchial tuberculosis (EBTB) have wheeze on physical examination and normal chest PA, which mimic bronchial asthma. Non-specific bronchial challenge tests have been used to confirm the presence of bronchial hyperreactivity, which ...
Jeong, S.W., Kim, K.U., Lee, S.M., Uh, S., Kim, H.T., Park, C.S., Kim, Y.H.   +6 more
core   +1 more source

Transformation of adrenal medullary chromaffin cells increases asthmatic susceptibility in pups from allergen-sensitized rats

Respiratory Research, 2012
Background Studies have shown that epinephrine release is impaired in patients with asthma. The pregnancy of female rats (dams) with asthma promotes in their pups the differentiation of adrenal medulla chromaffin cells (AMCCs) into sympathetic neurons ...
Feng Jun-Tao, Wu Xiu-Ming, Li Xiao-Zhao, Zou Ye-Qiang, Qin Ling, Hu Cheng-Ping   +5 more
doaj   +1 more source