Results 51 to 60 of about 17,482 (256)
Clinical effects of spa therapy were examined in 150 patients with asthma in relation tobronchial hyperresponsiveness and patient age. 1. The efficacy rate of spa therapy was larger as the patient age was higher: the rate was 73.3% in patients under age ...
Ashida, Kozo +8 more
core +1 more source
Th2 cytokines and asthma The role of interleukin-5 in allergic eosinophilic disease [PDF]
Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective cytokine as a result of the restricted expression of the interleukin-5 ...
Chapman Richard W +4 more
core +2 more sources
Perinatal respiratory infections and long term consequences
Respiratory syncytial virus (RSV) is the most important pathogen in the etiology of respiratory infections in early life. 50% of children are affected by RSV within the first year of age, and almost all children become infected within two years. Numerous
Luciana Indinnimeo, Valentina De Vittori
doaj +1 more source
Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer +12 more
core +1 more source
The usefulness of bronchial challenge tests in the diagnosis of occupational asthma
Bronchial hyperresponsiveness (BHR) is the individual ability to respond with bronchoconstriction to a variety of specific and nonspecific stimuli which do not cause these symptoms among healthy subjects.
Ewa Nowakowska-Świrta +2 more
doaj +1 more source
Antagonism of cytokine-induced eosinophil accumulation in asthma [PDF]
Peer reviewedPublisher ...
Walsh, Garry M.
core +2 more sources
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. [PDF]
Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain unclear. Human studies have correlated aberrant activation of T helper (Th) 2-like effector systems in the airways with disease. A
Corry, DB +6 more
core
Adenosine signaling in airways: Toward a promising antiasthmatic approach [PDF]
Adenosine participates to asthma physiopathology by signaling through more than just one receptor subtype. Defining the role of each receptor is complicated by evidence that often results obtained on rodents do not coincide with human studies, but what ...
CICALA, CARLA, IALENTI, ARMANDO
core +1 more source
ABSTRACT Background INTEGUMENT‐PED/NCT04845620, a 4‐week, phase 3 trial, demonstrated efficacy and safety of roflumilast cream 0.05% in children aged 2–5 years with mild‐to‐moderate atopic dermatitis (AD). A phase 3 open‐label extension trial (INTEGUMENT‐OLE [NCT04804605]) investigated long‐term outcomes continuing roflumilast cream for ≤ 56 weeks ...
Lawrence F. Eichenfield +14 more
wiley +1 more source
Salvinorin A Inhibits Airway Hyperreactivity Induced by Ovalbumin Sensitization [PDF]
Salvinorin A, a neoclerodane diterpene isolated from Salvia divinorum, exerts a number of pharmacological actions which are not solely limited to the central nervous system.
Bilancia, Rossella +10 more
core +1 more source

