Results 41 to 50 of about 17,482 (256)

IL-13R alpha 2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca2+ signaling [PDF]

, 2007
Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13R alpha 2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13R alpha 2 remains vague ...
Bergner, Albrecht, Gamarra, Fernando, Huber, Rudolf M., Joerres, Rudolf A., Kellner, Julia, Welsch, Ulrich   +5 more
core   +1 more source

Prevention of Antigen-Induced Bronchial Hyperreactivity and Airway Inflammation in Sensitized Guinea-Pigs by Tacrolimus

Mediators of Inflammation, 1999
We examined the effect of the immunosuppressive agent, tacrolimus (FK506), on antigen-induced bronchial hyperreactivity to acetylcholine and leukocyte infiltration into the airways of ovalbumin-challenged guinea-pigs.
J. R. Lapa e Silva, C. Ruffié, J. Lefort, M-A. Nahori, B. B. Vargaftig, M. Pretolani   +5 more
doaj   +1 more source

Protective effect of leukotriene receptor antagonist montelukast on smoking-induced lung injury in Wistar rats. [PDF]

, 2003
Increased activation of alveolar macrophage, neutrophil and mast cell has been proven in cigarette smoking (CS)-related lung disorders (CSLD). An increased production of cysteinyl-leukotrienes (LTs), which are mediators secreted from the mentioned cells,
Coskun, Senol, Ozbilgin, Kemal, Tuglu, Ibrahim, Yuksel, Hasan   +3 more
core   +1 more source

The role of the tachykinin NK1 receptor in airway changes in a mouse model of allergic asthma [PDF]

, 2004
A
De Swert, Katelijne, Joos, Guy, Pauwels, Romain, Tournoy, Kurt   +3 more
core   +2 more sources

Triphala (PADMA) extract alleviates bronchial hyperreactivity in a mouse model through liver and spleen immune modulation and increased anti-oxidative effects

Therapeutic Advances in Respiratory Disease, 2012
Objectives: Triphala (TRP), a herbal extract from Tibetan medicine, has been shown to affect lymphocytes and natural killer T (NKT) cell function. We hypothesize that TRP could ameliorate bronchial hyperreactivity through immune-cell modulations. Methods:
Amjad Horani, David Shoseyov, Isaac Ginsburg, Rufayda Mruwat, Sarit Doron, Johnny Amer, Rifaat Safadi   +6 more
doaj   +1 more source

Profile of reslizumab in eosinophilic disease and its potential in the treatment of poorly controlled eosinophilic asthma [PDF]

, 2013
Peer reviewedPublisher ...
Walsh, Garry Michael
core   +2 more sources

Influence of sensitization and allergen provocation procedures on the development of allergen-induced bronchial hyperreactivity in conscious, unrestrained guinea-pigs

Mediators of Inflammation, 1995
The effects of different sensitization and allergen provocation regimens on the development of allergen-induced bronchial hyperreactivity (BHR) to histamine were investigated in conscious, unrestrained guinea-pigs.
R. E. Santing, C. G. Olymulder, B. van Diepen, H. Meurs, J. Zaagsma   +4 more
doaj   +1 more source

Modulation of pulmonary allergic responses by mucosal cytokine–gene transfer* A summary of this review was presented at the Spring Meeting of the 8th Japanese Congress of Allergology. Originally published in the Journal of Immunology 1996; 157: 3216–19. Copyright 1996. The American Association of Immunologists. This article can not be reproduced in an electronic form.

Allergology International, 1997
Recent clinical and experimental animal studies have provided evidence for a pivotal role of T lymphocytes and Th2 cytokines in the development of allergic inflammatory responses and airway hyperreactivity.
Shau-Ku Huang, Xiu-Min Li
doaj   +1 more source

Airway obstruction and bronchial reactivity from age 1 month until 13 years in children with asthma: A prospective birth cohort study.

PLoS Medicine, 2019
BackgroundStudies have shown that airway obstruction and increased bronchial reactivity are present in early life in children developing asthma, which challenges the dogma that airway inflammation leads to low lung function. Further studies are needed to
Henrik Wegener Hallas, Bo Lund Chawes, Morten Arendt Rasmussen, Lambang Arianto, Jakob Stokholm, Klaus Bønnelykke, Hans Bisgaard   +6 more
doaj   +1 more source

FEATURES OF TRANSFORMATIONS OF RED BLOOD CELLS IN CHILDREN WITH BRONCHIAL ASTHMA

Медицинская иммунология, 2017
Increase prevalence of bronchial asthma (BA) is noted recently. That’s why its treatment remains an urgent problem in allergology. Along with congenital atopy, a significant role in formation and development of a disease is given to hyperreactivity of ...
E. N. Suprun, S. V. Suprun, O. E. Guseva, M. A. Loschenko, T. V. Pivkina, E. A. Savitskaya, S. V. Anuriev, V. A. Osmolkina, S. S. Braga   +8 more
doaj   +1 more source