Results 31 to 40 of about 79,822 (211)

The usefulness of bronchial challenge tests in the diagnosis of occupational asthma

Medycyna Pracy, 2018
Bronchial hyperresponsiveness (BHR) is the individual ability to respond with bronchoconstriction to a variety of specific and nonspecific stimuli which do not cause these symptoms among healthy subjects.
Ewa Nowakowska-Świrta, Marta Wiszniewska, Jolanta Walusiak-Skorupa   +2 more
doaj   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Influence of Environmental Pollution on Basophil Reactivity to Birch Pollen Allergens in Atopic and Non‐Atopic Subjects

Allergy, EarlyView.
Birch pollen and PM10 are key determinants of clinical symptoms, particularly in asthma. Allergic people react stronger to the pollen collected in the highly polluted area than in the less polluted areas. When evaluating the effectiveness of allergen immunotherapy, it is essential to consider not only pollen concentrations but also levels of air ...
Maria Czarnobilska, Małgorzata Bulanda, Ewa Czarnobilska, Wojciech Dyga, Marek Jutel, Dorota Myszkowska   +5 more
wiley   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Targeting pepsin provides superior protection to acid suppression in reflux‐associated airway inflammation and lung dysfunction

Experimental Physiology, EarlyView.
Abstract Gastro‐oesophageal reflux disease is a prevalent condition associated with extra‐oesophageal manifestations, such as pulmonary inflammation. Pepsin, an essential gastric enzyme, has been implicated in pulmonary complications owing to its inflammatory effects.
Thiago Meneses Araújo Leite Sales, Humberto Barbosa da Costa Filho, Kalinne Kelly Lima Gadelha, Kerolayne de Melo Nogueira, Álvaro Xavier Franco, Carlos Eduardo da Silva Monteiro, Maria Klayre Araújo de Sousa, Monalisa Cássias Souza, Isabele de Sá Silveira Melo, Lucas Antonio Duarte Nicolau, Marco Antonio de Freitas Clementino, Pedro Jorge Caldas Magalhães, Alexandre Havt, Pedro Marcos Gomes Soares, Daniel Sifrim, Marcellus Henrique Loiola Ponte de Souza   +15 more
wiley   +1 more source

Is beta-2 agonist induced bronchial hyperreactivity due to a concomitant exposure to allergens?

, 1991
Study on beta-2 agonist induced bronchial hyperreactivity due to a concomitant exposure to ...
Peroni, Diego, Spezia E, Bonizzato C, BONER, Attilio, Benedetti M, PIACENTINI, Giorgio, Sette L.   +6 more
core   +1 more source

CHRONIC NASAL HYPER-REACTIVITY (CURRENT CLASSIFICATIONS, CLINICAL PATTERN, DIAGNOSIS)

Медицинский совет, 2017
Nasal hyper-reactivity (NG) is a clinical phenomenon manifested by increased individual sensitivity of the nasal mucosa to factors that do not cause symptoms in healthy people.
E. P. MERKULOVA, S. N. KOLESNIKOVA
doaj   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

Bronchial hyperreactivity in systemic sclerosis patients: Influence of associated Sjogren's syndrome

, 1995
Objective-To determine the frequency and relative risk of bronchial hyperreactivity to methacholine in systemic sclerosis patients with or without associated Sjogren's syndrome.
LA CORTE, Renato, POTENA, Alfredo, BAJOCCHI G, TROTTA, Francesco, GOVONI, Marcello   +4 more
core   +1 more source