Results 31 to 40 of about 20,599 (182)

Risk factors for severe bronchiolitis in children less than 2 years old: a retrospective cohort study

Saudi Journal of Emergency Medicine, 2021
Background: Bronchiolitis is the most common reason for hospitalization and frequent cause of viral infection. This study aimed to determine the risk factors for severe bronchiolitis in children admitted through the emergency department at Sultan Qaboos ...
Niranjan Lal Jeswani, Sumaira Iram, Mohammed Ali Yezdan, Hilal Mohammed Al Barwani, Abdullah Al Reesi   +4 more
doaj   +1 more source

A brief focus on 2022 Italian guidelines on the management of bronchiolitis in infants

Global Pediatrics
The intersociety consensus document “UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants” aimed to update the previously published clinical practice guidelines on the prevention and treatment of bronchiolitis in newborns and ...
Sara Manti, Eugenio Baraldi
doaj   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Respiratory Syncytial Virus-Load Kinetics and Clinical Course of Acute Bronchiolitis in Hospitalized Infants: Interim Results and Review of the Literature

Pathogens, 2023
Respiratory Syncytial Virus (RSV) bronchiolitis is the leading cause of hospitalization in infants. The role of RSV load in disease severity is still debated.
Giulia Piccirilli, Alessandro Rocca, Eva Caterina Borgatti, Liliana Gabrielli, Daniele Zama, Luca Pierantoni, Marta Leone, Camilla Totaro, Matteo Pavoni, Tiziana Lazzarotto, Marcello Lanari   +10 more
doaj   +1 more source

Low‐value care and variation in practice in the care of children hospitalized with bronchiolitis in Canada (CareBEST): Protocol for a multi‐center prospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Introduction Low‐value care refers to health services for which the potential harms or costs outweigh the benefits of use. Bronchiolitis is the most common and among the most costly causes of pediatric hospitalizations. Evidence consistently shows that many common tests and treatments used to manage bronchiolitis do not improve outcomes ...
Branden Bonham, Tamara Perez, Michelle Bailey, Nick Barrowman, Christopher Bonafide, Ariane Boutin, Melanie Buba, Francine Buchanan, Matthew Carwana, Breanna A. Chen, Evelyn Constantin, Kim de Castris Garcia, Francesca del Giorgio, Zachary Dionisopoulos, Christine Fahim, Karen L. Forbes, Jeremy N. Friedman, Josée Anne Gagnon, Peter J. Gill, Mei Han, Nelly Huynh, Maria Karaceper, Terry P. Klassen, Isabelle Lahaie, Patricia Li, Myla Moretti, Sanjay Mahant, Sarah Manos, Hayat Mekhici, Chris Novak, Olivia Ostrow, Caroline Quach, Julie Quet, Mahmoud Sakran, Anupam Seghal, Alan R. Shroeder, Marc‐André Turcot, Gita Wahi, Olivier Drouin, The Canadian Pediatric Inpatient Research Network (PIRN)   +39 more
wiley   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Viral Bronchiolitis in Children: Less is More

Indian Journal of Critical Care Medicine, 2021
Jerath N. Viral Bronchiolitis in Children: Less is More. Indian J Crit Care Med 2021;25(11):1219-1220.
openaire   +2 more sources

Mixed Viral Infections Circulating in Hospitalized Patients with Respiratory Tract Infections in Kuwait

Advances in Virology, 2015
The aim of this study was to determine the frequency of viral mixed detection in hospitalized patients with respiratory tract infections and to evaluate the correlation between viral mixed detection and clinical severity.
Sahar Essa, Abdullah Owayed, Haya Altawalah, Mousa Khadadah, Nasser Behbehani, Widad Al-Nakib   +5 more
doaj   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Early online

South African Medical Journal, 2023
Bronchiolitis, a common reason for infant hospitalisation in South Africa (SA), is caused by viral pathogens. Bronchiolitis is typically an illness of mild to moderate severity that occurs in well-nourished children.
Ziyaad Dangor, Sanjay Lala, Charl Verwey, Gary Reubenson, Debbie White, David Moore, Prakash Jeena, Refileo Masekela, Heather Zar   +8 more
doaj   +1 more source