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Disease Severity of Respiratory Syncytial Virus Infection in Hospitalized Children. [PDF]

open access: yesViruses
Background: Respiratory syncytial virus (RSV) is a leading cause of hospitalization for acute respiratory tract infection (ARTI) in young children. Respiratory viral coinfections are frequently identified in RSV-related ARTIs, yet their impact on disease
Di Chiara C   +11 more
europepmc   +2 more sources

Rhinovirus increases Moraxella catarrhalis adhesion to the respiratory epithelium

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Rhinovirus causes many types of respiratory illnesses, ranging from minor colds to exacerbations of asthma. Moraxella catarrhalis is an opportunistic pathogen that is increased in abundance during rhinovirus illnesses and asthma exacerbations and is ...
Eishika Dissanayake   +11 more
doaj   +1 more source

Quercetin prevents rhinovirus-induced progression of lung disease in mice with COPD phenotype. [PDF]

open access: yesPLoS ONE, 2018
Acute exacerbations are the major cause of morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). Rhinovirus, which causes acute exacerbations may also accelerate progression of lung disease in these patients.
Mohammad Farazuddin   +5 more
doaj   +1 more source

Engineering the common cold to be a live-attenuated SARS-CoV-2 vaccine

open access: yesFrontiers in Immunology, 2022
According to the American Centers for Disease Control and Prevention, people in all age groups catch two or more “colds” per year, at least half of which are caused by human rhinoviruses.
Laura M. Kasman
doaj   +1 more source

Rhinovirus species and tonsillar immune responses

open access: yesClinical and Translational Allergy, 2019
Background Rhinovirus A and C infections are important contributors to asthma induction and exacerbations. No data exist on the interaction of local immune responses in rhinovirus infection. Therefore, we aimed to determine the tonsillar immune responses
Emilia Mikola   +11 more
doaj   +1 more source

Recent advances in understanding rhinovirus immunity [version 1; referees: 4 approved]

open access: yesF1000Research, 2018
Rhinoviruses are the most common cause of upper respiratory tract infections. However, they can induce exacerbations of chronic obstructive pulmonary disease and asthma, bronchiolitis in infants, and significant lower respiratory tract infections in ...
Spyridon Makris, Sebastian Johnston
doaj   +1 more source

Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells

open access: yesCells, 2022
Asthma is a chronic airway disease whose exacerbations are often triggered by rhinovirus infection. TGF-β1 induces rhinovirus replication in infected cells.
Susanne Krammer   +7 more
doaj   +1 more source

The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations.

open access: yesPLoS Pathogens, 2011
Rhinovirus infections are the major cause of asthma exacerbations. We hypothesised that IL-15, a cytokine implicated in innate and acquired antiviral immunity, may be deficient in asthma and important in the pathogenesis of asthma exacerbations.
Vasile Laza-Stanca   +9 more
doaj   +1 more source

Prevalence of rhinovirus in wheezing children: a comparison with respiratory syncytial virus wheezing

open access: yesBrazilian Journal of Infectious Diseases, 2016
Objective: To explore the distribution and clinical manifestations of rhinovirus infection in wheezing children, and compare the clinical differences between rhinovirus- and respiratory syncytial virus-induced wheezing.
Huiquan Sun   +8 more
doaj   +1 more source

Rhinovirus induces airway remodeling: what are the physiological consequences?

open access: yesRespiratory Research, 2023
Background Rhinovirus infections commonly evoke asthma exacerbations in children and adults. Recurrent asthma exacerbations are associated with injury-repair responses in the airways that collectively contribute to airway remodeling.
Cassandra Spector   +3 more
doaj   +1 more source

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