Results 41 to 50 of about 77,402 (234)

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections [PDF]

open access: yes, 2017
Background: Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B.
Agricola, Eleonora   +22 more
core   +1 more source

Airborne rhinovirus detection and effect of ultraviolet irradiation on detection by a semi-nested RT-PCR assay

open access: yesBMC Public Health, 2003
Background Rhinovirus, the most common cause of upper respiratory tract infections, has been implicated in asthma exacerbations and possibly asthma deaths. Although the method of transmission of rhinoviruses is disputed, several studies have demonstrated
Rudnick Stephen   +3 more
doaj   +1 more source

An Anti-Human ICAM-1 Antibody Inhibits Rhinovirus-Induced Exacerbations of Lung Inflammation [PDF]

open access: yes, 2013
Human rhinoviruses (HRV) cause the majority of common colds and acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Effective therapies are urgently needed, but no licensed treatments or vaccines currently exist.
A Papi   +56 more
core   +3 more sources

Identification of the Viral Pathogens in School Children With Acute Otitis Media in Central Java, Indonesia

open access: yesGlobal Pediatric Health, 2023
Acute otitis media (AOM) is one of the most common infectious diseases in pediatric clinical facilities and has a significant impact on health care. It is a polymicrobial disease and is usually preceded by a viral upper respiratory tract infection.
Anton Budhi Darmawan   +5 more
doaj   +1 more source

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation [PDF]

open access: yes, 2008
Rhinoviruses cause serious morbidity and mortality as the major etiological agents of asthma exacerbations and the common cold. A major obstacle to understanding disease pathogenesis and to the development of effective therapies has been the lack of a ...
A Papi   +57 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Ginsenoside Re protects rhinovirus-induced disruption of tight junction through inhibition of ROS-mediated phosphatases inactivation in human nasal epithelial cells

open access: yesHeliyon
Maintaining tight junction integrity significantly contributes to epithelial barrier function. If the barrier function is destroyed, the permeability of the cells increases, and the movement of the pathogens is promoted, thereby further increasing the ...
Kyeong Ah Kim   +3 more
doaj   +1 more source

Lower respiratory tract infections associated with rhinovirus during infancy and increased risk of wheezing during childhood. A cohort study.

open access: yesPLoS ONE, 2013
Background and objectivesAlthough association between respiratory syncytial virus infection and later asthma development has been established, little is known about the role of other respiratory viruses.
Cristina O'Callaghan-Gordo   +8 more
doaj   +1 more source

Disgust sensitivity is not associated with health in a rural Bangladeshi sample. [PDF]

open access: yes, 2014
Disgust can be considered a psychological arm of the immune system that acts to prevent exposure to infectious agents. High disgust sensitivity is associated with greater behavioral avoidance of disease vectors and thus may reduce infection risk. A cross-
A Hoefling   +34 more
core   +4 more sources

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

open access: yesAdvanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park   +11 more
wiley   +1 more source

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