Results 31 to 40 of about 60,470 (243)

Interference between rhinovirus and other RNA respiratory viruses in the first 2-years of life: A longitudinal community-based birth cohort study

, 2022
Background: Cross-sectional studies report negative associations between rhinovirus and other RNA respiratory viruses. However, longitudinal studies with frequent, serial sampling are needed to identify the directionality of this relationship and its ...
Stephen B. Lambert, Keith Grimwood, Robert S. Ware, Grimwood, Keith, Lambert, Stephen B, Mari D. Takashima, Peter D. Sly, Ware, Robert S, Takashima, Mari D, Sly, Peter D   +9 more
core   +1 more source

Human rhinovirus detection in the lower respiratory tract of hematopoietic cell transplant recipients: association with mortality

Haematologica, 2017
Human rhinoviruses are the most common respiratory viruses detected in patients after hematopoietic cell transplantation. Although rhinovirus appears to occasionally cause severe lower respiratory tract infection in immunocompromised patients, the ...
Sachiko Seo, Alpana Waghmare, Emily M Scott, Hu Xie, Jane M Kuypers, Robert C. Hackman, Angela P. Campbell, Su-Mi Choi, Wendy M. Leisenring, Keith R. Jerome, Janet A. Englund, Michael Boeckh   +11 more
doaj   +1 more source

Defining critical roles for NF‐κB p65 and type I interferon in innate immunity to rhinovirus

EMBO Molecular Medicine, 2012
The importance of NF‐κB activation and deficient anti‐viral interferon induction in the pathogenesis of rhinovirus‐induced asthma exacerbations is poorly understood.
Nathan W. Bartlett, Louise Slater, Nicholas Glanville, Jennifer J. Haas, Gaetano Caramori, Paolo Casolari, Deborah L. Clarke, Simon D. Message, Julia Aniscenko, Tatiana Kebadze, Jie Zhu, Patrick Mallia, Joseph P. Mizgerd, Maria Belvisi, Alberto Papi, Sergei V. Kotenko, Sebastian L. Johnston, Michael R. Edwards   +17 more
doaj   +1 more source

Rhinovirus exacerbates house-dust-mite induced lung disease in adult mice.

PLoS ONE, 2014
Human rhinovirus is a key viral trigger for asthma exacerbations. To date, murine studies investigating rhinovirus-induced exacerbation of allergic airways disease have employed systemic sensitisation/intranasal challenge with ovalbumin.
Jennifer A Phan, Anthony Kicic, Luke J Berry, Lynette B Fernandes, Graeme R Zosky, Peter D Sly, Alexander N Larcombe   +6 more
doaj   +1 more source

Population structure and evolution of Rhinoviruses.

PLoS ONE, 2014
Rhinoviruses, formerly known as Human rhinoviruses, are the most common cause of air-borne upper respiratory tract infections in humans. Rhinoviruses belong to the family Picornaviridae and are divided into three species namely, Rhinovirus A, -B and -C ...
Vaishali P Waman, Pandurang S Kolekar, Mohan M Kale, Urmila Kulkarni-Kale   +3 more
doaj   +1 more source

Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication

Nature Communications, 2022
Evidence exists that the typically antiviral signaling mediator STING is, counterintuitively, needed for optimal human rhinovirus infection. Here the authors confirm this finding and show how human rhinovirus can reduce stored Ca2+ levels to drive this ...
Martha Triantafilou, Joshi Ramanjulu, Lee M. Booty, Gisela Jimenez-Duran, Hakan Keles, Ken Saunders, Neysa Nevins, Emma Koppe, Louise K. Modis, G. Scott Pesiridis, John Bertin, Kathy Triantafilou   +11 more
doaj   +1 more source

Mechanism of Rhinovirus Immunity and Asthma

Frontiers in Immunology, 2021
The majority of asthma exacerbations in children are caused by Rhinovirus (RV), a positive sense single stranded RNA virus of the Picornavirus family.
Zuqin Yang, Hannah Mitländer, Tytti Vuorinen, Susetta Finotto   +3 more
doaj   +1 more source

Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response

, 2012
Rhinovirus (RV) infection is a major cause of asthma exacerbations which may be due to a deficient innate immune response in the bronchial epithelium. We hypothesized that the pleiotropic cytokine, TGF-?, influences interferon (IFN) production by primary
Green, Ben, David Sammut (137689), Gisli Jenkins (137696), Bedke Nicole, Jenkins Gisli, Stephen T Holgate, Donna E Davies, Howarth, Peter H., Nicole Bedke (137686), Sammut, David, Jenkins, Gisli, Amanda Tatler, Holgate, Stephen T., Sammut David, Ben Green, Patrick Dennison, Stephen T. Holgate (137701), Valia Kehagia, Dennison Patrick, Holgate Stephen T., David Sammut, Amanda Tatler (137698), Davies Donna E., Nicole Bedke, Donna E. Davies (137702), Bedke, Nicole, Peter H Howarth, Green Ben, Peter H. Howarth (137699), Patrick Dennison (137694), Davies, Donna E., Valia Kehagia (137692), Gisli Jenkins, Tatler, Amanda, Tatler Amanda, Howarth Peter H., Ben Green (137690), Dennison, Patrick, Kehagia, Valia, Kehagia Valia   +39 more
core   +1 more source

Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma.

PLoS ONE, 2017
Rhinovirus infection is associated with the majority of asthma exacerbations. The role of fractalkine in anti-viral (type 1) and pathogenic (type 2) responses to rhinovirus infection in allergic asthma is unknown.
Nadine Upton, David J Jackson, Alexandra A Nikonova, Suzie Hingley-Wilson, Musa Khaitov, Ajerico Del Rosario, Stephanie Traub, Maria-Belen Trujillo-Torralbo, Max Habibi, Sarah L Elkin, Onn M Kon, Michael R Edwards, Patrick Mallia, Joseph Footitt, Jonathan Macintyre, Luminita A Stanciu, Sebastian L Johnston, Annemarie Sykes   +17 more
doaj   +1 more source

Airborne rhinovirus detection and effect of ultraviolet irradiation on detection by a semi-nested RT-PCR assay

BMC Public Health, 2003
Background Rhinovirus, the most common cause of upper respiratory tract infections, has been implicated in asthma exacerbations and possibly asthma deaths. Although the method of transmission of rhinoviruses is disputed, several studies have demonstrated
Rudnick Stephen, Myatt Theodore A, Johnston Sebastian L, Milton Donald K   +3 more
doaj   +1 more source