Results 31 to 40 of about 64,944 (223)

Population structure and evolution of Rhinoviruses.

PLoS ONE, 2014
Rhinoviruses, formerly known as Human rhinoviruses, are the most common cause of air-borne upper respiratory tract infections in humans. Rhinoviruses belong to the family Picornaviridae and are divided into three species namely, Rhinovirus A, -B and -C ...
Vaishali P Waman, Pandurang S Kolekar, Mohan M Kale, Urmila Kulkarni-Kale   +3 more
doaj   +1 more source

Identification of the Viral Pathogens in School Children With Acute Otitis Media in Central Java, Indonesia

Global Pediatric Health, 2023
Acute otitis media (AOM) is one of the most common infectious diseases in pediatric clinical facilities and has a significant impact on health care. It is a polymicrobial disease and is usually preceded by a viral upper respiratory tract infection.
Anton Budhi Darmawan, Aghnianditya Kresno Dewantari BSc, Hanifah Fajri Maharani Putri BSc, Ageng Wiyatno M.Biomed, Daniel Joko Wahyono, Dodi Safari PhD   +5 more
doaj   +1 more source

Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response

, 2012
Rhinovirus (RV) infection is a major cause of asthma exacerbations which may be due to a deficient innate immune response in the bronchial epithelium. We hypothesized that the pleiotropic cytokine, TGF-?, influences interferon (IFN) production by primary
Green, Ben, David Sammut (137689), Gisli Jenkins (137696), Bedke Nicole, Jenkins Gisli, Stephen T Holgate, Donna E Davies, Howarth, Peter H., Nicole Bedke (137686), Sammut, David, Jenkins, Gisli, Amanda Tatler, Holgate, Stephen T., Sammut David, Ben Green, Patrick Dennison, Stephen T. Holgate (137701), Valia Kehagia, Dennison Patrick, Holgate Stephen T., David Sammut, Amanda Tatler (137698), Davies Donna E., Nicole Bedke, Donna E. Davies (137702), Bedke, Nicole, Peter H Howarth, Green Ben, Peter H. Howarth (137699), Patrick Dennison (137694), Davies, Donna E., Valia Kehagia (137692), Gisli Jenkins, Tatler, Amanda, Tatler Amanda, Howarth Peter H., Ben Green (137690), Dennison, Patrick, Kehagia, Valia, Kehagia Valia   +39 more
core   +1 more source

Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma.

PLoS ONE, 2017
Rhinovirus infection is associated with the majority of asthma exacerbations. The role of fractalkine in anti-viral (type 1) and pathogenic (type 2) responses to rhinovirus infection in allergic asthma is unknown.
Nadine Upton, David J Jackson, Alexandra A Nikonova, Suzie Hingley-Wilson, Musa Khaitov, Ajerico Del Rosario, Stephanie Traub, Maria-Belen Trujillo-Torralbo, Max Habibi, Sarah L Elkin, Onn M Kon, Michael R Edwards, Patrick Mallia, Joseph Footitt, Jonathan Macintyre, Luminita A Stanciu, Sebastian L Johnston, Annemarie Sykes   +17 more
doaj   +1 more source

Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication

Nature Communications, 2022
Evidence exists that the typically antiviral signaling mediator STING is, counterintuitively, needed for optimal human rhinovirus infection. Here the authors confirm this finding and show how human rhinovirus can reduce stored Ca2+ levels to drive this ...
Martha Triantafilou, Joshi Ramanjulu, Lee M. Booty, Gisela Jimenez-Duran, Hakan Keles, Ken Saunders, Neysa Nevins, Emma Koppe, Louise K. Modis, G. Scott Pesiridis, John Bertin, Kathy Triantafilou   +11 more
doaj   +1 more source

Mechanism of Rhinovirus Immunity and Asthma

Frontiers in Immunology, 2021
The majority of asthma exacerbations in children are caused by Rhinovirus (RV), a positive sense single stranded RNA virus of the Picornavirus family.
Zuqin Yang, Hannah Mitländer, Tytti Vuorinen, Susetta Finotto   +3 more
doaj   +1 more source

Airborne rhinovirus detection and effect of ultraviolet irradiation on detection by a semi-nested RT-PCR assay

BMC Public Health, 2003
Background Rhinovirus, the most common cause of upper respiratory tract infections, has been implicated in asthma exacerbations and possibly asthma deaths. Although the method of transmission of rhinoviruses is disputed, several studies have demonstrated
Rudnick Stephen, Myatt Theodore A, Johnston Sebastian L, Milton Donald K   +3 more
doaj   +1 more source

Pathogenesis of rhinovirus infection [PDF]

Current Opinion in Virology, 2012
Since its discovery in 1956, rhinovirus (RV) has been recognized as the most important virus producing the common cold syndrome. Despite its ubiquity, little is known concerning the pathogenesis of RV infections, and some of the research in this area has led to contradictions regarding the molecular and cellular mechanisms of RV-induced illness.
Joshua L, Kennedy, Ronald B, Turner, Thomas, Braciale, Peter W, Heymann, Larry, Borish   +4 more
openaire   +2 more sources

Antiviral therapeutic approaches for human rhinovirus infections [PDF]

, 2018
Human rhinoviruses are the primary etiological agent of the common cold. This infection can be mild and self-limiting in immunocompetent hosts, but can be associated with bronchiolitis in infants, pneumonia in the immunosuppressed and exacerbations of ...
Craig Stevens, Casanova, Victor, Victor Casanova, Barlow, Peter G, Stevens, Craig, Filipa H Sousa, Peter G Barlow, Sousa, Filipa H   +7 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source