Results 51 to 60 of about 20,599 (182)

Investigating the Role of A20 in Respiratory Syncytial Virus Immunopathogenesis in a BALB/c Mouse Model

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Respiratory syncytial virus (RSV) is a leading cause of acute respiratory tract infections in children and the elderly worldwide. RSV pathogenesis is largely driven by exaggerated host immune responses that result in lung injury.
Alireza Tahamtan, Mohammad Yasaghi, Saeed Samadizadeh, Hadi Razavi Nikoo, Ahad Yamchi, Vahid Salimi   +5 more
wiley   +1 more source

High rate of viral identification and coinfections in infants with acute bronchiolitis

Clinics, 2010
OBJECTIVES: To determine the viruses and risk factors associated with hospital and intensive care unit (ICU) admissions in infants with acute bronchiolitis. INTRODUCTION: Bronchiolitis is a major cause of morbidity in infants. Widespread use of molecular-
Milena Siciliano Nascimento, Andréa Vieira de Souza, Adriana Vada de Souza Ferreira, Joaquim Carlos Rodrigues, Sulim Abramovici, Luiz Vicente Ferreira da Silva Filho   +5 more
doaj   +1 more source

Virus, allergic sensitisation and cortisol in infant bronchiolitis and risk of early asthma

ERJ Open Research, 2020
Background Acute bronchiolitis during infancy and human rhinovirus (HRV) lower respiratory tract infections increases the risk of asthma in atopic children.
Jon Olav Gjengstø Hunderi, Leif Bjarte Rolfsjord, Karin C. Lødrup Carlsen, René Holst, Egil Bakkeheim, Teresa Løvold Berents, Kai-Håkon Carlsen, Håvard Ove Skjerven   +7 more
doaj   +1 more source

Steroid‐Refractory Cryptogenic Organising Pneumonia (COP) in a Patient With Mannose‐Binding Lectin (MBL) Deficiency

Respirology Case Reports, Volume 14, Issue 2, February 2026.
A 67‐year‐old man with cryptogenic organising pneumonia developed recurrent relapses despite corticosteroid and mycophenolate therapy. A complete absence of mannose‐binding lectin was identified, suggesting impaired apoptotic cell clearance as a contributor to persistent inflammation.
Ilias E. Dimeas, Sotirios I. Sinis, Paraskevi Kirgou, Cormac McCarthy, Zoe Daniil   +4 more
wiley   +1 more source

Etiology, Seasonality, and Clinical Features of Viral Respiratory Tract Infections in Children Hospitalized With Acute Bronchiolitis: A Single-Center Study

Global Pediatric Health, 2017
The purpose of this study was to evaluate the viral frequency, seasonality, and clinical and demographic features of patients hospitalized with acute bronchiolitis. A cross-sectional, descriptive study was performed in 316 infants younger than 2 years of
Şule Gökçe MD, Zafer Kurugöl PhD, Güldane Koturoğlu PhD, Candan Çiçek PhD, Aslı Aslan MD   +4 more
doaj   +1 more source

The Burden of Respiratory Syncytial Virus in Children With Acute Otitis Media: A Systematic Review and Meta‐Analysis

Influenza and Other Respiratory Viruses, Volume 20, Issue 2, February 2026.
ABSTRACT Background Acute otitis media (AOM) affects over 709 million individuals globally each year, more than half of whom are children < 5 years. Respiratory syncytial virus (RSV) is a leading viral cause of pediatric respiratory illness. We aimed to estimate the burden of RSV in children < 5 years with AOM Methods We performed a systematic review ...
Sebastien Kenmoe, Marshall Dozier, Jingyi Liang, Ruth Jenkins, Harish Nair   +4 more
wiley   +1 more source

The Effectiveness of Family Health Conversations Delivered by Nurses: A Systematic Review

Journal of Clinical Nursing, Volume 35, Issue 2, Page 539-564, February 2026.
ABSTRACT Aim To extract and interpret quantitative data exploring the effectiveness of family health conversations (FHCs) on family functioning, perceived support, health‐related quality of life, caregiver burden and family health in families living with critical or chronic health conditions.
Birte Østergaard, Erla Kolbrun‐Svavarsdottir, Anne Brødsgaard, Stine Rosenstrøm, Cristina Garcia‐Vivar, Hanne Konradsen, Karin Brochstedt‐Dieperink, Lorenz Imhof, Romy Mahrer‐Imhof, Marie Louise Luttik   +9 more
wiley   +1 more source

Modern Approaches in management of Children with Acute Bronchiolitis

Педиатрическая фармакология, 2020
The experts of the Union of Pediatricians of Russia have developed up-to-date clinical guidelines on management of children with acute bronchiolitis. Around 150 million cases of bronchiolitis (11 cases per 100 infants) are registered annually, 7–13 % of ...
Alexander A. Baranov, Leyla S. Namazova-Baranova, Vladimir K. Tatochenko, Irina V. Davydova, Maia D. Bakradze, Tatiana V. Kulichenko, E. V. Vishnyova, Liliya R. Selimzyanova, Anastasia S. Polyakova, Inga V. Artemova   +9 more
doaj   +1 more source

Bacterial Toxin Exploits Host Membrane Phospholipid as a Receptor for Binding, Entry, and Cytopathogenicity

Molecular Microbiology, Volume 125, Issue 2, Page 145-158, February 2026.
Mycoplasma pneumoniae pathogenesis relies on its CARDS toxin, which initiates cell binding and subsequent uptake by exploiting sphingomyelin, a key phospholipid found in the host plasma membrane. Maximal cellular entry and full cytotoxic effects are achieved through a synergistic mechanism that involves interaction with the protein coreceptor annexin ...
Alejandra M. Kirkpatrick, Thirumalai R. Kannan   +1 more
wiley   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source