Results 141 to 150 of about 7,178 (187)

10th International Conference on Bronchoalveolar Lavage

Revista Portuguesa de Pneumologia, 2007
doaj   +1 more source

Beyond the Wheeze: Incidental Diagnosis of Eosinophilic Oesophagitis in a Young Child With Asthma‐Like Symptoms

Journal of Paediatrics and Child Health, EarlyView.
Sameena Tabassum, Keslar Just, Mili Jyotsna, Anayansi Lasso‐Pirot   +3 more
wiley   +1 more source

Moderate maternal nutrient restriction alters type II alveolar epithelial cell density in the non‐human primate fetal lung

Experimental Physiology, EarlyView.
Abstract Restriction of fetal substrate supply has an adverse effect on surfactant maturation in the lung and thus affects the transition from in utero placental oxygenation to pulmonary ventilation ex utero. However, the consequences of reduced fetal substrate supply are dependent on the timing of gestation, severity and duration.
Mitchell C. Lock, Hillary F. Huber, Cun Li, Sandra Orgeig, Peter W. Nathanielsz, Janna L. Morrison   +5 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Proteomic Analysis of Golden Sputum Reveals Pulmonary Complement Activation During Acute Chest Syndrome in Children With Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 4, Page 678-686, April 2026.
ABSTRACT Acute chest syndrome (ACS) is one of the most common severe complications of sickle cell disease (SCD). In recent years, a major role of inflammation and innate immunity has been evidenced, but ACS pathophysiology remains incompletely understood, and therapeutic options are limited.
Slimane Allali, Nabiha Sbeih, Rachel Rignault‐Bricard, Johanna Bruce, Morgane Le Gall, Claire Heilbronner, Noemie de Cacqueray, Sofia Angyalosy, Melissa Taylor, Joséphine Brice, Mariane de Montalembert, Martina Bevacqua, Emilie‐Fleur Gautier, Olivier Hermine, Thiago Trovati Maciel   +14 more
wiley   +1 more source

Acute Invasive Pulmonary Aspergillosis With CNS Dissemination in an Immunocompetent Individual: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Invasive pulmonary aspergillosis can occur in patients without classical immunosuppression, particularly those with COPD and corticosteroid exposure. Early recognition, prompt antifungal therapy, and vigilance for neurological symptoms are essential to prevent central nervous system dissemination, which carries high mortality and significant ...
Barbare Khatiashvili, Sarah Saife, Islam Rajab, Malina Mohtadi, Arham Hazari, Ghassan Makhoul, Aqsa Zoey Sorathia, Ahmad Huzien, Shivanck Upadhyay   +8 more
wiley   +1 more source

Acute Respiratory Distress Syndrome in Adult Patient With RSV Infection: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT We described the case of a 54‐year‐old woman with no history of immunodeficiencies admitted to the ICU of our university hospital due to acute respiratory failure and ARDS secondary to severe community‐acquired pneumonia (sCAP) caused by RSV infection.
Gioacchina Martina Campione, Mario Alessio Guarano, Mariachiara Ippolito, Giulia Catalisano, Giulia Lo Scrudato, Ilenia Giacchino, Erika Mannino, Teresa Maria Assunta Fasciana, Giovanni Giammanco, Cesira Palmeri di Villalba, Santi Maurizio Raineri, Andrea Cortegiani, Antonino Giarratano   +12 more
wiley   +1 more source

Prophylactic Inhaled Pattern Recognition Receptor Agonists Reprogram Lung Epithelial Response and Prevent Type 2 Allergic Inflammation

European Journal of Immunology, Volume 56, Issue 4, April 2026.
Inhaled pretreatment of mouse lungs with immunomodulatory Pam2ODN results in lung epithelial cell epigenetic reprogramming that is associated with attenuation of house dust mite extract (HDM)‐induced cDC2s and moDCs expansion in the lung, causing tolerance against HDM sensitization and restricting Th2‐cell‐induced airway eosinophilic allergic ...
Mbaya Ntita, Celine Shuet Lin Kong, Dalia Hassan, Richa Nayak, Jezreel Pantaleón García, Yongxing Wang, Jichao Chen, Scott E. Evans   +7 more
wiley   +1 more source

The Potential of Bioinformatics in Revolutionizing Disease Diagnosis in Sub‐Saharan Africa: A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aim Despite its role in healthcare delivery and accessibility, the potential of bioinformatics to transform disease diagnosis in SSA remains unknown. This narrative review aims to assess the current status of bioinformatics initiatives in SSA and evaluate the role of bioinformatics in transforming diagnosis of major diseases in ...
Wilfred Ofosu, Fleischer C. N. Kotey, Alex Odoom, Onyansaniba K. Ntim, Eric S. Donkor   +4 more
wiley   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source