Results 41 to 50 of about 106,925 (231)

Cell-Free DNA and CXCL10 Derived from Bronchoalveolar Lavage Predict Lung Transplant Survival. [PDF]

, 2019
Standard methods for detecting chronic lung allograft dysfunction (CLAD) and rejection have poor sensitivity and specificity and have conventionally required bronchoscopies and biopsies.
Damm, Izabella, Liberto, Juliane M, Sarwal, Minnie M, Sarwal, Reuben D, Sigdel, Tara K, Vanaudenaerde, Bart M, Verleden, Geert M, Verleden, Stijn E, Vos, Robin, Watson, Drew, Yang, Joshua YC, Zarinsefat, Arya   +11 more
core   +2 more sources

Electronic nose analysis of bronchoalveolar lavage fluid

European Journal of Clinical Investigation, 2010
Eur J Clin Invest 2010; 41 (1): 52–58AbstractBackground  Electronic nose (E‐nose) technology has been successfully used to diagnose a number of microbial infections. We have investigated the potential use of an E‐nose for the diagnosis of ventilator‐associated pneumonia (VAP) by detecting micro‐organisms in bronchoalveolar lavage (BAL) fluid in a ...
Humphreys, L, Orme, R, Moore, P, Charaklias, N, Sahgal, N, Pont, N, Magan, N, Stone, N, Kendall, C   +8 more
openaire   +2 more sources

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Microbiota analysis optimization for human bronchoalveolar lavage fluid

Microbiome, 2019
Background It is now possible to comprehensively characterize the microbiota of the lungs using culture-independent, sequencing-based assays. Several sample types have been used to investigate the lung microbiota, each presenting specific challenges for ...
Pierre H. H. Schneeberger, Janice Prescod, Liran Levy, David Hwang, Tereza Martinu, Bryan Coburn   +5 more
doaj   +1 more source

Elevated peptides in lung lavage fluid associated with bronchiolitis obliterans syndrome. [PDF]

PLoS ONE, 2014
The objective of this discovery-level investigation was to use mass spectrometry to identify low mass compounds in bronchoalveolar lavage fluid from lung transplant recipients that associate with bronchiolitis obliterans syndrome.Bronchoalveolar lavage ...
Matthew D Stone, Stephen B Harvey, Gary L Nelsestuen, Cavan Reilly, Marshall I Hertz, Chris H Wendt   +5 more
doaj   +1 more source

気管支肺胞洗浄液中リンパ球増多と患者年齢およびIgE系アレルギー反応との関連について [PDF]

, 1993
The proportion and number of lymphocytes in the airways were analyzed in 15 patients with a high proportion of lymphocytes in bronchoalveolar lavage (BAL) fluid (more than 30%) and in 17 patients with less than 20% of BAL lymphocytes. 1.
Kimura, Ikuro, Kitani, Hikaru, Mifune, Takashi, Mitsunobu, Fumihiro, Tanizaki, Yoshiro   +4 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Vascular Endothelial Growth Factor‐121 Administration Mitigates Halogen Inhalation‐Induced Pulmonary Injury and Fetal Growth Restriction in Pregnant Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Circulating levels of sFLT‐1 (soluble fms‐like tyrosine kinase 1), the extracellular domain of vascular endothelial growth factor (VEGF) receptor 1, and its ratio to levels of placental growth factor are markers of the occurrence and severity ...
Dylan R. Addis, James A. Lambert, Changchun Ren, Stephen Doran, Saurabh Aggarwal, Tamas Jilling, Sadis Matalon   +6 more
doaj   +1 more source

Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis

Advanced Science, EarlyView.
Inhaled antisense oligonucleotides targeting ANGPTL4 attenuate inflammation, preserve barrier integrity, and reduce fibrosis in both infectious and sterile lung injury models. Integrated transcriptomic analysis reveals a conserved ANGPTL4‐regulated gene network coordinating hypoxic, inflammatory, apoptotic, and stress‐response pathways.
Haiyang Fan, Yuanyang Tan, Junhang Zhang, Xiaoya Liu, Jing Qu, Damien Chua, Hong Sheng Cheng, Joseph Han Sol Kim, Yu Xuan Liu, Changfei Qin, Yingzi Liu, Dezhi Li, Jikang Qiu, Mengshi Chi, Mingmin Bi, Qiwei Zhang, Yun Li, Masoumeh Motamedi Joibari, Stefan K Nilsson, Nguan Soon Tan, Yunping Fan, Liang Li   +21 more
wiley   +1 more source

Association between lymphocyte count in bronchoalveolar lavage fluid and mortality

Journal of Intensive Care, 2021
This is a comment on the paper by Dr. Hirasawa et al. on the predictive value of lymphocyte counts in bronchoalveolar lavage fluid in patients with acute respiratory failure.
Yifu Si, Juqin Shao, Caibao Hu
doaj   +1 more source