Results 51 to 60 of about 110,976 (348)

Lateral Flow Assays for the Diagnosis of Invasive Aspergillosis: Current Status. [PDF]

open access: yes, 2017
Purpose of reviewDiagnosis during early stages of invasive aspergillosis (IA) and targeted antifungal treatment has the potential to improve survival significantly.
Heldt, Sven, Hoenigl, Martin
core   +1 more source

A Multi‐Center Retrospective Cohort Study of Neurosarcoidosis Myelitis: Current Observations and Future Directions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales. Methods Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers.
Giovanna S. Manzano   +39 more
wiley   +1 more source

Human Bocavirus (HBoV) Infection: An associated Life Threatening Respiratory illness

open access: yesJournal of Pediatric Critical Care, 2018
Background: 10 month old infant presenting with fever, cough and coryza for 3 days progressed to acute respiratory failure. An initial clinical presentation of wheeze associated lower respiratory tract infection developed into an extremely severe course ...
G Suryanarayana, S Sumithra, A V Lalitha
doaj   +1 more source

The cellular composition of the lung lining fluid gradually changes from bronchus to alveolus

open access: yesRespiratory Research, 2021
Although large advances have recently been made mapping out the cellular composition of lung tissue using single cell sequencing, the composition and distribution of the cellular elements within the lining fluid of the lung has not been extensively ...
S. D. Pouwels   +3 more
doaj   +1 more source

Candidacidal factors in murine bronchoalveolar lavage fluid [PDF]

open access: yesInfection and Immunity, 1987
Respiratory secretions provide an efficient method for protecting the large surface area of the lower respiratory tract. To determine whether lung secretions contribute to antifungal defenses, we tested bronchoalveolar lavage fluid for fungicidal activity.
K M Nugent, R B Fick
openaire   +3 more sources

Experimental Pulmonary Granuloma Mimicking Sarcoidosis Induced by Propionibacterium acnes in Mice [PDF]

open access: yes, 2010
Propionibacterium acnes has been implicated as an etiologic agent of sarcoidosis since the isolation of this bacterium from sarcoid lesions. We experimentally produced a murine pulmonary granuloma model using P.
Ichikawa, Hirohisa   +9 more
core   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer   +10 more
wiley   +1 more source

Cell-Free DNA and CXCL10 Derived from Bronchoalveolar Lavage Predict Lung Transplant Survival. [PDF]

open access: yes, 2019
Standard methods for detecting chronic lung allograft dysfunction (CLAD) and rejection have poor sensitivity and specificity and have conventionally required bronchoscopies and biopsies.
Damm, Izabella   +11 more
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Prognostic Implications of Bronchoalveolar Fluid Analysis in Ventilator-Associated Pneumonia: An Observational Cohort Study

open access: yesEgyptian Journal of Critical Care Medicine, 2022
Background Ventilator-associated pneumonia (VAP) is one of the most frequent infections with high mortality rates in intensive care units (ICUs) and the prediction of outcome is paramount in the decision-making process. Objective To assess the prognostic
Walid M. Kamel   +3 more
doaj   +1 more source

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