Results 91 to 100 of about 32,302 (223)

Performance of a word labeled visual analog scale in determining the degree of dyspnea during exercise-induced bronchoconstriction in children and adolescents with asthma [PDF]

, 2010
OBJECTIVE: There is an indirect relationship between airway obstruction in asthma and the intensity of breathlessness (dyspnea). A word labeled visual analog dyspnea scale with a 0-3 score has been widely used for the assessment of the degree of ...
Cabral, Anna Lúcia De Barros, Caetano, Lilian Ballini, Fernandes, Ana Luisa Godoy, Lima, Patrícia Bueno, Santoro, Ilka Lopes   +4 more
core   +2 more sources

Fentanyl Compromises Lower‐Airway Mechanics and Naloxone Triggers a Transient Mechanical Overshoot

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Opioid‐induced respiratory depression (OIRD) is the leading cause of death following opioid overdose, due to its effects on central rhythm generation, and airway and thoracic constriction. While the effects on rhythm generation have been well documented, the effects of fentanyl on airway constriction are less well understood. We tested the
Riley R. Parks, Marissa J. Andersen, Mackenna L. Hatfield, Madeline M. Johnson, Nicholas J. Burgraff   +4 more
wiley   +1 more source

bronchoconstriction

Citation: 'bronchoconstriction' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15525 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

The inhibitory effect of anti-allergic agent suplatast tosilate (IPD–1151T) on methacholine- and allergen-induced bronchoconstriction in sensitized mice

Mediators of Inflammation, 2000
The influence of an anti-allergic agent, suplatast tosilate (IPD-1151T; (±)-[2-[4-(3-ethoxy–2-hydroxypropoxy)phenyl-carbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate) on allergic bronchoconstriction induced by allergen and methacholine (MCh) were ...
Kazuhito Asano, Tetsuya Mizutani, Toshikazu Shimane, Masataka Hisano, Tadashi Hisamitsu, Harumi Suzaki   +5 more
doaj   +1 more source

Verapamil Induces Calcium Influx in the Trachea

Journal of Pharmacological Sciences, 2008
Verapamil, a Ca2+entry blocker, can induce bronchorelaxation and bronchoconstriction. The mechanism of verapamil-induced bronchoconstriction is poorly understood.
Seham Mustafa, Abdulkareem Abdulraheem, Abdulhakeem Alsughayer   +2 more
doaj   +1 more source

Patients' practices and experiences of using nebuliser therapy in the management of COPD at home. [PDF]

, 2015
How patients use their nebulisers at home is vital to ensure effective treatment and optimal health outcomes for patients with chronic obstructive pulmonary disease (COPD).
Alhaddad, B, Robertson, T, Smith, FJ, Taylor, KM, Watman, G   +4 more
core   +1 more source

Completion of the Icatibant Outcome Survey and What We Learned

Clinical &Experimental Allergy, EarlyView.
Laurence Bouillet, Werner Aberer, Teresa Caballero, Anete S. Grumach, Hilary J. Longhurst, Alissa Dangel, Natalie Khutoryansky, Irmgard Andresen, Andrea Zanichelli   +8 more
wiley   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, Volume 183, Issue 11, Page 2660-2674, June 2026.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Effects of Muscarinic Receptor Antagonists With or Without M2 Antagonist Activity on Cholinergic Reflex Bronchoconstriction in Ovalbumin-Sensitized and -Challenged Mice

Journal of Pharmacological Sciences, 2003
To investigate whether the inhibition of muscarinic M2 receptors results in the enhancement of reflex bronchoconstriction under airway hyperresponsiveness, we evaluated the effects of muscarinic antagonists with or without M2 antagonist activity on ...
Hiroyasu Hirose, Jian Jiang, Masaru Nishikibe   +2 more
doaj   +1 more source

Influence of environmental temperature and humidity on the acute ventilatory response to exercise in asthmatic adolescents [PDF]

, 2011
Asthma is a chronic inflammatory disorder of the respiratory airways affecting people of all ages, and constitutes a serious public health problem worldwide (6).
Appell, Hans Joachim, Duarte, José A., Silva, Ana   +2 more
core   +1 more source