Results 81 to 90 of about 32,302 (223)

Methacholine causes reflex bronchoconstriction [PDF]

Journal of Applied Physiology, 1999
To determine whether methacholine causes vagally mediated reflex constriction of airway smooth muscle, we administered methacholine to sheep either via the bronchial artery or as an aerosol via tracheostomy into the lower airways. We then measured the contraction of an isolated, in situ segment of trachealis smooth muscle and determined the effect of ...
E M, Wagner, D B, Jacoby
openaire   +2 more sources

Steamed hay for the prevention of severe equine asthma exacerbations

Equine Veterinary Journal, EarlyView.
Abstract Background Steaming hay reduces respirable particles and is commonly used to feed horses with asthma. However, it showed inconsistent benefits in clinical studies. Objectives (1) To assess the effects of steamed hay on lung function and airway inflammation in horses with severe equine asthma (SEA) in remission; (2) To compare these effects ...
Clara Raïsky, Berta Mozo Vives, Laurence Leduc, Antoine Symoens, Hamid Tavanaeimanesh, Hélène Richard, Tristan Juette, Christian Bédard, Mathilde Leclère   +8 more
wiley   +1 more source

The effect of the tachykinin NK2 receptor antagonist MEN11420 (nepadutant) on neurokinin A-induced bronchoconstriction in asthmatics

Therapeutic Advances in Respiratory Disease, 2009
Objective: We previously reported that the nonpeptide tachykinin NK 2 receptor antagonist SR48968 (saredutant) significantly inhibits neurokinin A-induced bronchoconstriction in patients with asthma. MEN11420 (nepadutant) is a bicyclic peptide tachykinin
Venessa Schelfhout, Veerle Van De Velde, Carlo Maggi, Romain Pauwels, Guy Joos   +4 more
doaj   +1 more source

Fish Oil Supplementation Reduces Markers of Oxidative Stress But Not Muscle Soreness After Eccentric Exercise [PDF]

, 2014
Peer ...
Chappell, Andrew John, Gray, Patrick, Gray, Stuart Robert, Jenkinson, Alison McEwan, Thies, Frank   +4 more
core   +1 more source

Field‐applicable low‐intensity exercise induces bronchodilation in horses with severe asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Sophie Mainguy‐Seers, Sarah‐Maude Grondin, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Indicators of the bronchial lability and hyperreactivity in children with bronchial asthma and exercise induced bronchoconstriction [PDF]

, 2014
The results of the analysis of the bronchial hyperreactivity indicators in 60 children suffering from asthma with exercise induced bronchoconstriction and without exercise induced bronchospasm are presented in the article.
Bogutska, N.K., Koloskova, O.K., Shahova, O.O.   +2 more
core  

Phase 2 trial of montelukast for prevention of pain in sickle cell disease. [PDF]

, 2020
Cysteinyl leukotrienes (CysLTs) are lipid mediators of inflammation. In patients with sickle cell disease (SCD), levels of CysLTs are increased compared with controls and associated with a higher rate of hospitalization for pain. We tested the hypothesis
Brandow, Amanda, Bryant, Valencia, DeBaun, Michael R, Embury, Stephen H, Field, Joshua J, Kassim, Adetola, Matsui, Neil, Simpson, Pippa, Wilkerson, Karina, Zhang, Liyun   +9 more
core  

How to perform open tracheal suction via an endotracheal tube [PDF]

, 2016
Rationale and key points Tracheal suction involves the removal of pulmonary secretions from the respiratory tract using negative pressure under sterile conditions.
Credland, Nicola
core   +1 more source

Medical Management With Mechanical Ventilation of a Dog With Severe Barium Sulfate Aspiration

Journal of Veterinary Emergency and Critical Care, EarlyView.
Abstract Objective To describe the medical management with mechanical ventilation of a dog with severe barium sulfate aspiration and concurrent canine acute eosinophilic dermatitis with edema. Case summary A 26‐month‐old castrated male Golden Retriever was presented in respiratory distress after the accidental administration of approximately 300 mL of ...
Mathieu V. Paulin, Allison A. Foster, Jennifer M. Loewen   +2 more
wiley   +1 more source

Preventing acute asthmatic symptoms by targeting a neuronal mechanism involving carotid body lysophosphatidic acid receptors

Nature Communications, 2018
Acute bronchoconstriction is the leading cause of asthmatic sudden death following allergen exposure. The authors show that the systemic increase of LPA following inhaled allergen or bradykinin challenge activates the carotid bodies through TRPV1 and LPA-
Nicholas G. Jendzjowsky, Arijit Roy, Nicole O. Barioni, Margaret M. Kelly, Francis H. Y. Green, Christopher N. Wyatt, Richard L. Pye, Luana Tenorio-Lopes, Richard J. A. Wilson   +8 more
doaj   +1 more source