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Treatment of Exercise-Induced Bronchoconstriction

Immunology and Allergy Clinics of North America, 2013
Exercise-induced bronchoconstriction (EIB) describes the transient narrowing of the airways during, and particularly after exercise and occurs commonly in asthmatic individuals. Limitation of exercise capacity is a frequent complaint in all age groups, and severity of EIB ranges from mild impairment of performance to severe bronchospasm and a large ...
Backer, Vibeke   +2 more
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Pathophysiology of Asthmatic Bronchoconstriction

CHEST Journal, 1982
T he major resistance airways of human subjects are innervated by at least three different types of autonomic nerves. The specific physiologic “advantage” to this homeostatic system for regulation of bronchomotor tone is uncertain; however, some degree of bronchomotor tone results from parasympathetic innervation in all normal individuals.
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The Homeostatic Rôle of Bronchoconstriction

Respiration, 2001
This article argues in favour of the hypothesis that the homeostatic rôles of bronchoconstriction are to retract the airway tree during expiration, and to assist in the expulsion of mucus from peripheral airways by increasing the velocity of outgoing air.
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Perception of Bronchoconstriction in Elderly Asthmatics

Journal of Asthma, 2001
The impaired perception of bronchoconstriction in asthmatic patients may increase the risk of severe exacerbation. To characterize the perception of bronchoconstriction in elderly asthma patients, we compared the perception in older patients with that of younger patients.
Ekici, M.   +3 more
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Effects of Ketotifen on in vitro bronchoconstriction

Clinical & Experimental Allergy, 1985
SummaryWe have studied the effects of Ketotifen [Ke](10−4M and 10−6M) on two in vitro models of bronchoconstriction: actively sensitized guinea‐pig trachea (GPT), and passively sensitized human bronchial muscle (HBM). Experiments were performed on matched pairs of tissues.
J. F. Costello   +3 more
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Testing for Exercise-Induced Bronchoconstriction

Immunology and Allergy Clinics of North America, 2018
Exercise-induced bronchoconstriction (EIB) is a form of airway hyperresponsiveness that occurs with or without current symptoms of asthma. EIB is an indicator of active and treatable pathophysiology in persons with asthma. The objective documentation of EIB permits the identification of an individual who may be at risk during a recreational sporting ...
Brannan, John D., Porsbjerg, Celeste
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Bronchoconstriction Reflex in Bronchial Asthma

1976
Our results suggest a presumably predominant role of the parasympathetic nervous system in the mechanism of human bronchial asthma. Bronchial reaction of the immediate type, induced by a specific antigen in allergic patients, can be partially but significantly prevented by a previous parasympathetic efferent blockade.
L. Nagy, K. Vass, E. Vastag
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Exercise-induced bronchoconstriction: Pathogenesis

Current Allergy and Asthma Reports, 2005
There is still active debate on the acute mechanism of exercise-induced bronchoconstriction (EIB). Although it is unlikely that vasoconstriction and hyperemia of the bronchial vasculature are essential events for EIB, it is likely that this vasculature enhances the airway response to dehydration and contributes to the pathogenesis of EIB, particularly ...
Sandra D. Anderson, Pascale Kippelen
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Bronchoconstriction due to 8-methoxypsoralen

British Journal of Dermatology, 1988
A patient with psoriasis developed bronchoconstriction after oral 8-methoxypsoralen given as part of his photochemotherapy with PUVA. It was possible to treat the patient with PUVA whilst he was on prophylactic anti-asthmatic therapy. Twenty one further patients on photochemotherapy were studied in detail and none had evidence of impaired pulmonary ...
B. Ramsay, Janet Marks
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Pathogenesis of Exercise-Induced Bronchoconstriction

Immunology and Allergy Clinics of North America, 2013
This article presents the various potential mechanisms responsible for the development of exercise-induced bronchoconstriction (EIB). Although the etiology of EIB is multifactorial, and the physiologic processes involved may vary between individuals (especially between those with and without asthma), drying of the small airways with an associated ...
Sandra D. Anderson, Pascale Kippelen
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