Results 21 to 30 of about 23,197 (178)

Aeroacoustic sound alteration in airway bronchoconstriction, represented by a constricted T-branch model

Journal of Biomechanical Science and Engineering, 2015
Lung sound is commonly analyzed when testing for lung abnormalities. However, the accuracy of this analysis is low and more information on sound generation and alteration is needed to improve the analysis quality.
Gabriel Pramudita SAPUTRA, Kazunori NOZAKI, Satoshi II, Shigeo WADA   +3 more
doaj   +1 more source

Childhood Asthma in Nigeria: A Review of the Burden and Challenges of Management

Annals of Health Research, 2020
Bronchial asthma care professionals all over the world are faced with many challenges in managing children with asthma. This narrative review highlights the burden and specific challenges encountered by Nigerian health care professionals in the care of ...
Kuti BP
doaj   +1 more source

Approach to the diagnosis and management of suspected exercise-induced bronchoconstriction by primary care physicians [PDF]

, 2009
BACKGROUND: Exercise-related respiratory symptoms in the diagnosis of exercise-induced bronchoconstriction (EIB) have poor predictive value. The aim of this study was to evaluate how athletes presenting with these symptoms are diagnosed and managed in
Parsons, Jonathan, Ansley, Les, Parsons, Jonathan P., Hull, James H, Parsons, Jonathan P, Hull James H, Peter J Hull, Les Ansley, Dickinson, John W, Dickinson John W, Hull, James, Hull, Peter, John W Dickinson, Ansley Les, Parsons Jonathan P, James H Hull, Jonathan P Parsons, Hull, James H., Dickinson, John W., Hull Peter J, Hull, Peter J, Hull, Peter J.   +21 more
core   +2 more sources

Urinary CC16 after challenge with dry air hyperpnoea and mannitol in recreational summer athletes [PDF]

, 2013
Airway epithelial injury is regarded as a key contributing factor to the pathogenesis of exercise-induced bronchoconstriction (EIB) in athletes. The concentration of the pneumoprotein club cell (Clara cell) CC16 in urine has been found to be a non ...
Pascale Kippelen, Leena Ali, Ali, Leena, Anderson, Sandra D., Bjermer, Leif, Tufvesson, E, Bjermer, L, Tufvesson, Ellen, Ali, L, Kippelen, P, Kippelen, Pascale, Leif Bjermer, Sandra D. Anderson, Anderson, SD, Ellen Tufvesson   +14 more
core   +1 more source

Experimental evaluation of the nonselective and selective TMEM16 family calcium-activated chloride channel blockers in the airways

European Pharmaceutical Journal, 2023
The family of calcium-activated chloride channels, TMEM16, plays a significant role in contributing to the pathogenesis of airway inflammatory diseases.
Mažerik J., Smieško L., Fedorová L., Gondáš E.   +3 more
doaj   +1 more source

Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction

FASEB BioAdvances, 2020
The calcium‐activated chloride channel (CaCC) TMEM16A enables chloride secretion across several transporting epithelia, including in the airways. Additional roles for TMEM16A have been proposed, which include regulating mucus production and secretion and
Henry Danahay, Roy Fox, Sarah Lilley, Holly Charlton, Kathryn Adley, Lee Christie, Ejaz Ansari, Camille Ehre, Alexis Flen, Michael J. Tuvim, Burton F. Dickey, Colin Williams, Sarah Beaudoin, Stephen P Collingwood, Martin Gosling   +14 more
doaj   +1 more source

Effect of exercise‐induced bronchoconstriction on the configuration of the maximal expiratory flow‐volume curve in adults with asthma

Physiological Reports, 2023
We determined the effect of exercise‐induced bronchoconstriction (EIB) on the shape of the maximal expiratory flow‐volume (MEFV) curve in asthmatic adults. The slope‐ratio index (SR) was used to quantitate the shape of the MEFV curve.
Oksana Klimenko, Peter Luu, Paolo Dominelli, Nathan Noggle, Gregory Petrics, Hans Christian Haverkamp   +5 more
doaj   +1 more source

Possibility of lipid microsphere-encapsulated Y-24180 as an injectable drug and an inhaler for the treatment of bronchoconstriction

Allergology International, 2000
Y-241 80 ((±)-4-(2-chloro-phenyl)-2-[2-(4-isobuthyl- phenyl)ethyl]-6,9-dimethyl-6H-thieno[3,2f][1,2,4] triazolo[4,3-a)[1,4]diazepine) is a lipophilic platelet- activating factor (PAF) antagonist.
Mitsuko Takenaga, Rie Igarashi, Yutaka Mizushima   +2 more
doaj   +1 more source

Mechanisms and Biomarkers of Exercise-Induced Bronchoconstriction. [PDF]

, 2018
Exercise is a common trigger of bronchoconstriction. In recent years, there has been increased understanding of the pathophysiology of exercise-induced bronchoconstriction.
Hallstrand, TS, Pascale Kippelen, Kippelen, P, Sandra D. Anderson, Teal S. Hallstrand, Anderson, SD   +5 more
core   +1 more source

Is there agreement on the pathogenesis / pathophysiology of exercise induced asthma? [PDF]

, 2009
Purpose: Exercise Induced Asthma was formally proposed as a concept to the medical profession in 1966. However up to 1990 two different hypotheses were being put forward to explain the mechanism involved.
Caulfield, Una
core   +2 more sources