Results 41 to 50 of about 32,302 (223)

New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma [PDF]

, 2017
Introduction: Inhaled corticosteroids (ICS) alone or in combination with an inhaled long-acting beta2-agonist (LABA) are the preferred long-term treatment for adults and adolescents with symptomatic asthma.
Thomson, Neil C.
core   +1 more source

Leukotriene C4-Synthesis Deficiency

Pediatric Neurology Briefs, 1998
A leukotriene C4-synthesis deficiency, a new inborn error of eicosanoid metabolism characterized by hypotonia, microcephaly, failure to thrive, and retarded development, is described in an infant who died aged 6 months after a rapidly progressive course ...
J Gordon Millichap
doaj   +1 more source

A new role for exhaled nitric oxide as a functional marker of peripheral airway caliber changes: a theoretical study

, 2017
Though considered as an inflammation marker, exhaled nitric oxide (FENO) was shown to be sensitive to airway caliber changes to such an extent that it might be considered as a marker of them. It is thus important to understand how these changes and their
Haut, Benoît, Karamaoun, Cyril, Van Muylem, Alain   +2 more
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Acetylcholine-treated murine dendritic cells promote inflammatory lung injury [PDF]

, 2019
In recent years a non-neuronal cholinergic system has been described in immune cells, which is often usually activated during the course of inflammatory processes. To date, it is known that Acetylcholine (ACh), a neurotransmitter extensively expressed in
Alcain, Julieta María, Candolfi, Marianela, Geffner, Jorge Raúl, Gori, María Soledad, Jancic, Carolina Cristina, Moreno Ayala, Mariela Alejandra, Salamone, Gabriela Veronica, Vanzulli, Silvia, Vermeulen, Elba Monica   +8 more
core   +1 more source

Serum IgE as a Biomarker of Severity and Short-term Treatment Response in Steroid-naïve Children with Asthma: A Hospital-based Prospective Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Paediatric asthma is a growing public health challenge in Low- and Middle-Income Countries (LMICs), with increasing prevalence and substantial morbidity.
Kishore Alagesan, Prasanna Raju, Vaishnavi Sivaji, Preethi Suresh, Padmanaban Srinivasan, Subash Sundar   +5 more
doaj   +1 more source

The Bronchoprotective Effects of Dual Pharmacology, Muscarinic Receptor Antagonist and β₂ Adrenergic Receptor Agonist Navafenterol in Human Small Airways

Cells, 2023
Bronchodilators and anti-inflammatory agents are the mainstream treatments in chronic obstructive and pulmonary disease (COPD) and asthma.
Joseph Antony Jude, Ian Dainty, Nikhil Karmacharya, William Jester, Reynold Panettieri   +4 more
doaj   +1 more source

Mechanical correlates of dyspnea in bronchial asthma. [PDF]

, 2013
We hypothesized that dyspnea and its descriptors, that is, chest tightness, inspiratory effort, unrewarded inspiration, and expiratory difficulty in asthma reflect different mechanisms of airflow obstruction and their perception varies with the severity ...
A., Antonelli, C., Gulotta, Dellaca', Raffaele, E., Crimi, G., Scano, Gobbi, Alessandro, R., Pellegrino, R., Torchio, V., Brusasco   +8 more
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Anticholinergic therapy for acute asthma in children. [PDF]

, 2012
Inhaled anticholinergics as single agent bronchodilators (or in combination with beta(2)-agonists) are one of the several medications available for the treatment of acute asthma in ...
Beakes, Beck, Benito Fernandez, Bever, Bratteby, British Thoracic Society, Brown, Browne, Calvo, Cook, Craven, Cugell, DeStefano, Ducharme, Everard, Goggin, Gross, Guill, Hayday, Iramain, Lew, Lin, Lung, Mallol, McDonald, Mirsadraee, National Asthma Council Australia, Ni, Plotnick, Pulejo, Quereshi, Qureshi, Rayner, Reisman, Rodrigo, Schuh, Sienra Monge, Storms, Storr, Tal, Timsit, Ulrik, Undem, Wade, Ward, Ward, Yeung, Youngchaiyud, Zimmerman, Zorc   +49 more
core   +2 more sources

Approach to the diagnosis and management of suspected exercise-induced bronchoconstriction by primary care physicians [PDF]

, 2009
Background Exercise-related respiratory symptoms in the diagnosis of exercise-induced bronchoconstriction (EIB) have poor predictive value. The aim of this study was to evaluate how athletes presenting with these symptoms are diagnosed and managed in ...
James H Hull, Peter J Hull, Jonathan P Parsons, John W Dickinson, Les Ansley, JW Dickinson, JP Parsons, JH Hull, SD Anderson, K Holzer, KW Rundell, SD Anderson, JP Parsons, LB Schwartz, H Johansson, KH Carlsen, KD Fitch, K Holzer, I Helenius, SD Anderson, M Sue-Chu, TD Mickleborough, TD Mickleborough, TD Mickleborough, M Cullen, P Greenway, P Laure   +26 more
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高齢者気管支喘息における気道過敏性と温泉療法 [PDF]

, 2001
Clinical effects of spa therapy were examined in 150 patients with asthma in relation tobronchial hyperresponsiveness and patient age. 1. The efficacy rate of spa therapy was larger as the patient age was higher: the rate was 73.3% in patients under age ...
Ashida, Kozo, Hosaki, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Ochi, Koji, Okamoto, Makoto, Takata, Shingo, Tanizaki, Yoshiro, Tsugeno, Hirofumi   +8 more
core   +1 more source