Results 121 to 130 of about 20,702 (286)

Peak Expiratory Flow and Its Trajectories Associated With Frailty in Older Adults: A Prospective Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Current evidence indicates an association between peak expiratory flow (PEF) and frailty in older adults, yet critical gaps persist regarding: the longitudinal dynamics of PEF trajectories, their temporal relationships with frailty progression and underlying biological mechanisms.
Dingchun Hou, Bo Liang, Kai Zhao, Ye Zhang, Minglang Lang, Zhiqin Xu, Hezhang Yun, Weijun Yang, Longqi Yu, Chang Liu   +9 more
wiley   +1 more source

Evaluating bronchodilator response in pediatric patients with post-infectious bronchiolitis obliterans: use of different criteria for identifying airway reversibility

Jornal Brasileiro de Pneumologia
Objective: Post-infectious bronchiolitis obliterans (PIBO) is a clinical entity that has been classified as constrictive, fixed obstruction of the lumen by fibrotic tissue.
Rita Mattiello, Paula Cristina Vidal, Edgar Enrique Sarria, Paulo Márcio Pitrez, Renato Tetelbom Stein, Helena Teresinha Mocelin, Gilberto Bueno Fischer, Marcus Herbert Jones, Leonardo Araújo Pinto   +8 more
doaj   +1 more source

Are there specific clinical characteristics associated with physician’s treatment choices in COPD?

Respiratory Research, 2019
Background The number of pharmacological agents and guidelines available for COPD has increased markedly but guidelines remain poorly followed. Understanding underlying clinical reasoning is challenging and could be informed by clinical characteristics ...
Nicolas Roche, Anestis Antoniadis, David Hess, Pei Zhi Li, Eric Kelkel, Sylvie Leroy, Christophe Pison, Pierre-Régis Burgel, Bernard Aguilaniu, COLIBRI COPD Research Group   +9 more
doaj   +1 more source

Effect of different bronchodilators on airway smooth muscle responsiveness to contractile agents. [PDF]

, 1991
B. Gustafsson, C. G. A. Persson
openalex   +1 more source

Integrative GWAS and Mendelian Randomization Analysis Identifies IREB2 and CD27+ Memory B Cells as Core Drivers of COPD to Lung Cancer Progression

MedComm, Volume 6, Issue 12, December 2025.
This flowchart outlines our integrative pipeline. We linked COPD phenotypes and lung function with lung cancer in NHANES, then applied GWAS, Mendelian Randomization (MR), and colocalization to identify shared loci and driver genes. Candidate genes were refined by eQTL and single‐cell RNA‐seq analyses, and key findings validated in human tissues and B ...
Erkang Yi, Qingyang Li, Wenqian Wu, Chengshu Xie, Hairong Wang, Erping Long, Fan Wu, Xuanyi Lu, Yu Liu, Ruiting Sun, Xinqing Lin, Xiaohong Xie, Yumin Zhou, Chengzhi Zhou, Pixin Ran   +14 more
wiley   +1 more source

Equivalência farmacêutica da formulação combinada de budesonida e formoterol em cápsula única com dispositivo inalador de pó Pharmaceutical equivalence of the combination formulation of budesonide and formoterol in a single capsule with a dry powder inhaler

Jornal Brasileiro de Pneumologia, 2012
OBJETIVO: Avaliar a equivalência farmacêutica da formulação teste (associação fixa de budesonida e fumarato de formoterol em cápsula única dispensada com o dispositivo Aerocaps®) em relação a uma formulação referência (budesonida e fumarato de formoterol
Marina Andrade-Lima, Luiz Fernando Ferreira Pereira, Ana Luisa Godoy Fernandes   +2 more
doaj   +1 more source

Air Pollution‐Induced Epigenetic Regulation in Respiratory Diseases: Mechanisms, Dysregulation, and Therapeutic Opportunities

MedComm – Future Medicine, Volume 4, Issue 4, December 2025.
Air pollution, a major global health hazard, contributes to asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and lung cancer via four core epigenetic pathways (DNA/RNA methylation, noncoding RNAs, and histone modifications), shaping gene expression and driving disease pathogenesis.
Ruitong Zeng, Jiliu Liu, Guoping Li, Junyi Wang, Anying Xiong, Ying Xiong, Xiang He   +6 more
wiley   +1 more source

Applying High‐Dimensional Propensity Scores in a Study of Inhaled Corticosteroids and COVID‐19 Outcomes

Pharmacoepidemiology and Drug Safety, Volume 34, Issue 12, December 2025.
ABSTRACT Background In pharmacoepidemiologic studies of COVID‐19, there were concerns about bias from residual confounding. We investigated the effects of inhaled corticosteroids (ICS) on COVID‐19 outcomes, applying high‐dimensional propensity scores (HDPS) to adjust for unmeasured confounding.
Marleen Bokern, John Tazare, Christopher T. Rentsch, Jennifer K. Quint, Ian J Douglas, Anna Schultze   +5 more
wiley   +1 more source

Indacaterol/glycopyrronium versus salmeterol/fluticasone in Asian patients with COPD at a high risk of exacerbations: results from the FLAME study

International Journal of COPD, 2017
Jadwiga A Wedzicha,1 Nanshan Zhong,2 Masakazu Ichinose,3 Michael Humphries,4 Robert Fogel,5 Chau Thach,5 Francesco Patalano,6 Donald Banerji5 1National Heart and Lung Institute, Imperial College London, London, UK; 2State Key Laboratory of Respiratory ...
Wedzicha JA, Zhong N, Ichinose M, Humphries M, Fogel R, Thach C, Patalano F, Banerji D   +7 more
doaj  

A Novel Questionnaire and Algorithm for Work‐Related Asthma Screening and Surveillance: An EAACI Task Force Report

Allergy, Volume 80, Issue 12, Page 3260-3273, December 2025.
ABSTRACT Introduction Work‐related exposures contribute to one in six new‐onset adult asthma cases and exacerbation of one in five existing cases, which together are termed ‘work‐related asthma’ (WRA). A valid and standardized WRA questionnaire is needed for workplace surveillance and epidemiological studies.
Mohamed F. Jeebhay, Hille Suojalehto, Susan M. Tarlo, Eva Suarthana, Paul Cullinan, Irmeli Lindström, Paola Mason, Xavier Munoz, Monika Raulf, Marcela Valverde, Jolanta Walusiak‐Skorupa, Paul Henneberger   +11 more
wiley   +1 more source