Results 161 to 170 of about 3,193,785 (231)

ChemInform Abstract: TRICYCLIC QUINUCLIDYLIDENES AS POTENTIAL ANTIHISTAMINE‐BRONCHODILATING AGENTS

Chemischer Informationsdienst, 1975
AbstractAus den Oxo‐Verbindungen (I) erhält man mit 3‐Chlorchinuclidin (II) in Gegenwart von Na die Carbinole (III), aus (IV) erhält man über das Li‐Derivat mit 3‐Chinuclidon (V) die Carbinole (VI).
F. J. Villani   +2 more
openaire   +4 more sources

Efficacy of bronchodilator therapy in bronchiolitis. A meta-analysis.

Archives of Pediatrics & Adolescent Medicine, 1996
OBJECTIVE To determine if bronchodilators are efficacious in treating bronchiolitis. DATA SOURCES A search of bibliographic databases (MEDLINE, Excerpta Medica, and Reference Update) for bronchiolitis and albuterol or ipratropium bromide, or adrenergic
J. Kellner   +3 more
semanticscholar   +1 more source

LG 30435 is a new bronchodilator agent with multiple sites of action

European Journal of Pharmacology, 1986
LG 30435, a new quaternary derivative of the H1-histamine antagonist mequitazine, was evaluated against bronchospasm induced by different agonists. This compound inhibited equipotently methacholine- and histamine-induced contractions of isolated guinea-pig trachea. When administered to guinea-pig by the i.v. and/or the aerosol route, LG 30435 inhibited
Marco Criscuoli   +2 more
openaire   +3 more sources

Anticholinergic, antimuscarinic bronchodilators.

American Review of Respiratory Disease, 2015
The anticholinergic, antimuscarinic compounds are potent and hitherto neglected bronchodilators. Although atropine itself has drawbacks, principally related to its rapid absorption and consequent systemic side effects, its quaternary ammonium congeners ...
N. Gross, M. Skorodin
semanticscholar   +1 more source

Benzopyranopyridine derivatives. 1. Aminoalkyl derivatives of the azaxanthenes as bronchodilating agents

Journal of Medicinal Chemistry, 1975
The preparation of the four isomeric azaxanthones 3 and a number of their aromatic ring substituted derivatives is described. These ketones were converted into the title compounds which were examined for their biological properties. The most interesting compound in this series, the 1-methyl-4-piperidylidene derivative of 1-azaxanthene, shows the ...
F J, Villani   +11 more
openaire   +3 more sources

The variable effect of a bronchodilating agent on pulmonary function in cystic fibrosis

The Journal of Pediatrics, 1973
Nine of 50 patients with cystic fibrosis were found to have a measurable response to bronchodilators. The maximum expiratory flow-volume curve was the most sensitive test for detecting it. Of these nine patients, five improved and could be considered to have an associated asthmatic diathesis.
L.I. Landau, P.D. Phelan
openaire   +3 more sources

Characteristics of airway inflammation and bronchodilator reversibility in COPD: a potential guide to treatment.

Chest, 2004
STUDY OBJECTIVES The management of stable patients with COPD depends on the severity of symptoms and airflow limitation. Regarding inflammation, corticosteroids are the only medications that are recommended for use, and only under restricted ...
D. Perng   +4 more
semanticscholar   +1 more source

Bronchodilator effect of inhaled formoterol vs salbutamol over 12 hours.

Chest, 1990
The bronchodilator effects were compared in 16 stable asthma patients for 12 hours after either 12 micrograms formoterol or 200 micrograms salbutamol from a metered-dose aerosol in a randomized, double-blind, crossover study.
Francis P.V. Maesen   +3 more
semanticscholar   +1 more source

Tiotropium bromide: a novel once-daily anticholinergic bronchodilator for the treatment of COPD.

Drugs of Today, 2002
Tiotropium bromide (Spiriva, BA679BR, Boehringer Ingelheim) is a novel inhaled, long-acting anticholinergic bronchodilator that is employed as a once-daily maintenance treatment for patients with chronic obstructive pulmonary disease (COPD).
T. Hansel, P. Barnes
semanticscholar   +1 more source

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